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Changes in Trabecular Bone Score and Their Determinants in Young and Middle-aged Men: A Longitudinal Observational Study AbstractObjective. To study bone turnover markers (BTM) and sex steroids in relation to trabecular bone score (TBS) in men.Material and Methods. Longitudin

Changes in Trabecular Bone Score and Their Determinants in Young and Middle-aged Men: A Longitudinal Observational Study Get access Arrow. Read more in #JCEM: bit.ly/4b0Ei8I #TrabecularBoneScore #BoneTurnoverMarkers #SexSteroids @endocrinesociety.bsky.social

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Impact of Minimal Dose Strategy Before Antithyroid Drug Discontinuation on Relapse Risk in Graves’ Disease AbstractBackground. Although antithyroid drugs (ATDs) are widely used as the first-line therapy for Graves’ disease, relapse after treatment discontinuatio

Impact of Minimal Dose Strategy Before Antithyroid Drug Discontinuation on Relapse Risk in Graves’ Disease. Read more in #JCEM: bit.ly/3MSCTcb #GravesDisease #Methimazole #AntiThyroidDrugs @endocrinesociety.bsky.social

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Sex Hormones Mediate Intensive Lifestyle Intervention–Induced Bone Mineral Density Changes: Look AHEAD Sex Hormone Study AbstractContext. The Look AHEAD (Action in Health for Diabetes) randomized controlled trial, which compared an Intensive Lifestyle Intervention (ILI) to Di

Sex Hormones Mediate Intensive Lifestyle Intervention–Induced Bone Mineral Density Changes: Look AHEAD Sex Hormone Study Get access Arrow. Read more in #JCEM: bit.ly/4aL2Baz #Mediation #SexHormones #diabetes @endocrinesociety.bsky.social

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Severe Refractory Calcitriol-Mediated Hypercalcemia in Diffuse Large B-Cell Lymphoma Treated With Hemodialysis Abstract. Hypercalcemia of malignancy is a recognized complication of diffuse large B-cell lymphoma (DLBCL) and is associated with decreased survival time

Severe Refractory Calcitriol-Mediated Hypercalcemia in Diffuse Large B-Cell Lymphoma Treated With Hemodialysis. Read more in #JCEM Case Reports: bit.ly/4kJwigJ #nonHodgkinLymphoma #calcitriol #HypercalcemiaofMalignancy @endocrinesociety.bsky.social

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Endocrine Feedback Loop Podcast | Listen to Andrew Crawford, MD, and Giuseppe Barbesino, MD, discuss a recent #JCEM article (https://bit.ly/4kImBz4 on the impact of low doses of methimazole to predict or even cause a sustained remission in Graves’ disease: https://bit.ly/EFL070

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The Role of Cortisol Secretion in Pheochromocytomas and Paragangliomas: Clinical and Perioperative Implications AbstractBackground. Pheochromocytomas and paragangliomas (PPGLs) are tumors marked by excessive catecholamine secretion. Patients with pheochromocytomas ma

The Role of Cortisol Secretion in Pheochromocytomas and Paragangliomas: Clinical and Perioperative Implications. Read more in #JCEM: bit.ly/4kTQw7x #Paraganglioma #CardiovascularDisease #MetanephrineConcentrations @endocrinesociety.bsky.social

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Parathyroidectomy Restores Muscle Strength and Transcriptome in Individuals With Primary Hyperparathyroidism AbstractContext. Primary hyperparathyroidism leads to hypercalcemia and muscle dysfunction. Muscle weakness is associated with increased morbidity and mort

Parathyroidectomy Restores Muscle Strength and Transcriptome in Individuals With Primary Hyperparathyroidism. Read more in #JCEM: bit.ly/3LBzNsD #Parathyroidectomy #MuscleStrength #PrimaryHyperparathyroidism @endocrinesociety.bsky.social

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Genetic Risk and Transition Through Preclinical Stages of Type 1 Diabetes AbstractContext. The influence of genetic factors on the transition through preclinical stages of type 1 diabetes (T1D) has not been studied.Objective. Our

Genetic Risk and Transition Through Preclinical Stages of Type 1 Diabetes. Read more in #JCEM: bit.ly/4baJpVA #EarlyType1DiabetesMarkers #GeneticRiskFactors #Type1Diabetes @endocrinesociety.bsky.social

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Insulin Levels Linked To Hot Flashes, Night Sweats In Menopause TUESDAY, Feb. 3, 2026 (HealthDay News) — Middle-aged women with elevated insulin levels might be in for a tougher menopause experience, a new study says.Women w

Women with elevated insulin levels face a higher risk of experiencing menopausal symptoms at a younger age, according to research published in #JCEM. Via @healthday.bsky.social @endocrinesociety.bsky.social @endosocjournals.bsky.social bit.ly/4bU1Myv #menopause #EndoSky

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High Body Mass Index as a Causal Risk Factor for Vascular-Related Dementia: A Mendelian Randomization Study AbstractContext. Obesity is associated with a high risk of vascular-related dementia with metabolic risk factors as potential mediators, but questions of c

In new genetic study, Liv Tybjærg Nordestgaard, et al. analyzed data from large populations in Denmark and the U.K., and found that #Obesity & #HighBloodPressure may play a direct role in causing #Dementia, not just increasing the risk. Learn More in #JCEM 👉 academic.oup.com/jcem/advance...

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Endocrine Feedback Loop Podcast | Listen to Ashok Balasubramanyam, MD, and Åke Lernmark, MD, PhD, discuss an article (https://bit.ly/4t4u5QE on the gut microbiome of adolescents with type 1 diabetes: https://bit.ly/EFL069 #JCEM #obesity #diabetes

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Clinical Significance of Successful Ablation in Follicular Thyroid Carcinoma AbstractContext. Outcomes of postoperative ablation focused on follicular thyroid carcinoma (FTC) have not been fully investigated.Objective. The purpose o

Clinical Significance of Successful Ablation in Follicular Thyroid Carcinoma. Read more in #JCEM: bit.ly/49MN4Xk #FollicularThyroidCarcinoma #PostoperativeAblation @endocrinesociety.bsky.social

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New study directly links higher BMI to increased risk of vascular dementia; blood pressure may help explain why "What is good for the heart is good for the brain," one researcher says.

Research published in #JCEM explores how #obesity can raise dementia risk. Via ABC News: bit.ly/4pWF5gr @endocrinesociety.bsky.social @endosocjournals.bsky.social #EndoSky

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Scientists discover new clue linking obesity to dementia risk European researchers trace a path that shows how high blood pressure caused by excess weight could be the link to certain cognitive brain disease.

Breaking news: #JCEM study finds new evidence for link between #obesity and dementia risk. Via @washingtonpost.com bit.ly/4r5ZJLM @endocrinesociety.bsky.social @endosocjournals.bsky.social #EndoSky

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Beneficial Effects of Carbohydrate Restriction in Type 2 Diabetes Can Be Traced to Changes in Hepatic Metabolism AbstractContext. Carbohydrate restriction benefits metabolic health in patients with type 2 diabetes (T2D), possibly through changes in hepatic metabolism.

Beneficial Effects of Carbohydrate Restriction in Type 2 Diabetes Can Be Traced to Changes in Hepatic Metabolism. Read more in #JCEM: bit.ly/3ZtMust #KetogenicDiet #Type2Diabetes #LiverFat #DeNovoLipogenesis @endocrinesociety.bsky.social

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People with Obesity May Have a Higher Risk of Dementia - Endocrine News People with obesity and high blood pressure may face a higher risk of dementia, according to a new study published in The Journal of Clinical Endocrinology & Metabolism. Dementia is a growing global p...

People with obesity and high blood pressure may face a higher risk of dementia, according to a new study published in #JCEM. Read more in @endocrinenews.bsky.social: https://bit.ly/4sU6MJ8

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Testosterone Effects on Short-term Physical, Hormonal, and Neurodevelopmental Outcomes (TESTO) in Infants With 47,XXY AbstractContext. 47,XXY/Klinefelter syndrome (XXY) is associated with impaired testicular function and differences in physical growth, metabolism, and neur

Testosterone Effects on Short-term Physical, Hormonal, and Neurodevelopmental Outcomes (TESTO) in Infants With 47,XXY. Read more in #JCEM: bit.ly/4pMPiga #KlinefelterSyndrome #testosterone #MiniPubertyPeriod @endocrinesociety.bsky.social

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New Directions in Thyroid Care: Minimizing Risk, Maximizing Choice - Endocrine News From how radioiodine therapy for Graves’ disease impacts cancer occurrence and the potential usefulness of pharmacologic treatment for benign thyroid nodules to how a minimally invasive procedure coul...

As #Thyroid Awareness Month begins, three studies in #JCEM offer new insights into the management of common thyroid conditions, from the promise of noninvasive drug therapies to reassurance about the safety of established treatments. #EndoSky

endocrinenews.endocrine.org/new-directio...

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Markedly Melanin-Pigmented Paraganglioma Associated With Decreased Dopa-Decarboxylase Expression Abstract. A 49-year-old woman undergoing evaluation for sigmoid colon cancer was incidentally found to have a 56-mm retroperitoneal tumor. Although asympto

Markedly Melanin-Pigmented Paraganglioma Associated With Decreased Dopa-Decarboxylase Expression. Read more in #JCEM Case Reports: bit.ly/4j30oLt #PigmentedTumor #Paraganglioma #Pheochromocytoma @endocrinesociety.bsky.social

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Outcomes and Therapeutic Strategies for Head-and-neck Paragangliomas Associated With Succinate Dehydrogenase Mutations. Read more in #JCEM: bit.ly/48Rs0yg #Paraganglioma #Radiotherapy #TumoralProgression @endocrinesociety.bsky.social

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Enhanced Radiological Detection of a Corticotroph Adenoma Following Treatment With Osilodrostat Abstract. In approximately 30% of patients with Cushing disease, pituitary magnetic resonance imaging (MRI) does not reliably identify a corticotroph adeno

Enhanced Radiological Detection of a Corticotroph Adenoma Following Treatment With Osilodrostat. Read more in #JCEM Case Reports: bit.ly/48px3pq #CushingDisease #Osilodrostat #CorticotrophAdenoma @endocrinesociety.bsky.social

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Changes in A1C Versus GMI Across Glycemic Categories in Clinical Trials of Type 1 Diabetes AbstractContext. The glucose management indicator (GMI) is an estimated glycated hemoglobin (A1C) derived from sensor glucose. Though it is being used to a

Changes in A1C Versus GMI Across Glycemic Categories in Clinical Trials of Type 1 Diabetes. Read more in #JCEM: bit.ly/4pLcGKt #Type1Diabetes #ContinuousGlucoseMonitor #GlycemicVariability

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Longitudinal study of plasma metabolites during menopause and their associations with later onset of metabolic syndrome AbstractContext. Previous metabolomics studies suggest potential associations between menopausal changes in lipids and an increased risk of metabolic syndr

Longitudinal study of plasma metabolites during menopause and their associations with later onset of metabolic syndrome #JCEM #MassSpec academic.oup.com/jcem/article...

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Effects of 1-Month Very-Low-Calorie Ketogenic Diet on 24-Hour Energy Metabolism and Body Composition in Women With Obesity AbstractContext. Very-low-calorie ketogenic diet (VLCKD) is used for weight loss and management of obesity-related comorbidities.Objective. We aimed at eva

Effects of 1-Month Very-Low-Calorie Ketogenic Diet on 24-Hour Energy Metabolism and Body Composition in Women With Obesity. Read more in #JCEM: bit.ly/4pN5GwM #obesity #respiratory #KetogenicDiet @endocrinesociety.bsky.social

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Novel GLP-1-based Medications for Type 2 Diabetes and Obesity Abstract. The approvals of semaglutide and tirzepatide have set new benchmarks in the treatment of type 2 diabetes and obesity. Building on their success,

Novel GLP-1-based Medications for Type 2 Diabetes and Obesity. Read more in #JCEM: bit.ly/481iNV3 #Glucagon-Like-Peptide-1 #GLP-1 #amylin #obesity @endocrinesociety.bsky.social

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Risk of Death and Adverse Effects in Patients on Liothyronine: A Multisource Systematic Review and Meta-analysis. Read more in #JCEM: bit.ly/44t3Nga #hypothyroidism #liothyronine #cardiovascular

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Women with persistent #thyroid hormone imbalance across pregnancy may be at an increased risk of having children with #autism, according to a new study published in #JCEM. Read more in @endocrinenews.bsky.social: https://bit.ly/3KnTl2P

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Check out our review on osteoporosis and race in #JCEM @endosocjournals.bsky.social

academic.oup.com/jcem/article...

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Machine Learning–Based Biomarker Identification for Early Diagnosis of Metabolic Dysfunction–Associated Steatotic Liver Disease AbstractContext. Metabolic dysfunction–associated steatotic liver disease (MASLD) is an umbrella term for simple hepatic steatosis and the more severe meta

Machine Learning–Based Biomarker Identification for Early Diagnosis of Metabolic Dysfunction–Associated Steatotic Liver Disease. Read more in #JCEM: bit.ly/4hFjmqA #MASLD #hepaticfibrosis #biomarker @endocrinesociety.bsky.social

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@pandeylab.bsky.social , @unibe.ch
study in #JCEM @endosocjournals.bsky.social
novel POR G88S mutation causing severe #PORD. 🧬

Beyond the disorder, this mutation creates a critical pharmacogenomic risk 💊⚠️

gene-to-clinic story: doi.org/10.1210/clin...

#Endocrinology #RareDisease

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