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I teach medical students that fatty liver disease (MASLD) affects 1 in 3 adults and has limited approved drug treatments.

That may be changing.

Hebrew University researchers fo... www.sciencedaily.com/releases/2026/03/2603061...

#FattyLiver #MASLD #CBD #MetabolicHealth #LiverDisease

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🔥HOT TOPIC in #HEPATOLOGY

Selected for its clinical impact, this meta-analysis delivers critical insights into which anti-diabetic therapies may also reduce liver-related events in patients with #MASLD.

Read the full study here: https://bit.ly/4s40EgD

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Understanding MASLD: The Increasing Rise of Metabolic Liver Disease Explained by Dr. Karen Jerome-Zapadka This article delves into MASLD, an alarming rise in liver disease in the United States, with expert insights from Dr. Karen Jerome-Zapadka.

Understanding MASLD: The Increasing Rise of Metabolic Liver Disease Explained by Dr. Karen Jerome-Zapadka #United_States #Liver_Disease #MASLD #Cranberry_Township #Dr._Jerome-Zapadka

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The April 2026 issue of @lancetgastrohep.bsky.social is out today at www.thelancet.com/gastrohep

This month's issue features content on #IBD, #cirrhosis, #pancreaticcancer, #viralhepatitis, #MASLD + more...

#GastroSky #MedSky #LiverSky

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#MASLD in kidney transplant recipients #KTR is associated with worse patient and graft survival

www.kireports.org/article/S2468-0249(26)02...

#transplant #medicine #nephrology

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➡️ Nearly 1 in 3 #MASLD patients missed fibrosis risk–based care. Our study shows how AI-augmented workflows could reduce these gaps by automating steatosis detection, FIB-4 scoring, and referral alerts.
🔗 https://ow.ly/9T4u50YrxM2
🏷️ #FeaturedArticle

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🧪 Did you know that 1 in 5 people living with #T2D have a degree of #fibrosis?

Prof. Kenneth Cusi urges clinicians to screen for and prevent #MASLD from progressing to cirrhosis #ADAConsensusReport.

📺 Watch the latest #ExpertInsights episode now: easd-elearning.eu/episode/361/...

#Liverhealth

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Prenatal prednisone exposure promotes #MASLD in offspring via #GR-HDAC3-mediated #Serpina3c suppression, activating the #Chymase-AngII-AT1R axis to disrupt lipid metabolism, marking #Serpina3c as a critical #TherapeuticTarget.

#STTT #OpenAccess: doi.org/10.1038/s413...

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#MASLD patients’ Health Literacy Questionnaire data were analyzed with clinical/demographic data. This suggested that lower health literacy is associated with more advanced MASLD/metabolic dysfunction.
🔗 https://ow.ly/HSjp50YrxF8
🏷️ #EditorsEssentialReading

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Longitudinal Changes in Fibrosis Markers: Monitoring Stiffness/Fibrosis Progression and Prognostic Outcomes in MASLD Fibrosis-4 Index (FIB-4) is a noninvasive tool for assessing liver fibrosis in metabolic dysfunction-associated steatotic liver disease (MASLD). Howev…

#FIB-4 is widely used for #fibrosis assessment. But what about its changes over time?📈

🌏 A large international study shows how dynamic #FIB-4 may predict fibrosis progression and clinical outcomes in #MASLD
💡 Interesting implications for clinical practice!

📖: www.sciencedirect.com/science/arti...

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MASLD and viral hepatitis overlap: An emerging dual burden in chronic liver disease — Hepatology Forum Hepatology Forum is an open access journal publishing clinical and translational research in hepatology and liver diseases.

#MASLD and #HBV overlap tackled in this article - lots of questions remaining in how to assess and treat this emerging dual threat to global #liver health 🧪
#MedSKy #LiverSky #HepSky #hepatitis
hepatologyforum.org/article/257

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Parental obesity and risk of metabolic dysfunction associated steatotic liver disease in adult offspring: UK birth cohort study Background Metabolic dysfunction associated steatotic liver disease (MASLD), the most common chronic liver disease globally, may originate early in life. While maternal obesity is linked to offspring ...

Adiposidad paterna en exceso antes del embarazo se asocia con mayor probabilidad de hepatopatía esteatósica asociada a la disfunción metabólica en los descendientes mediada por el IMC infantil en exceso #parents #MASLD gut.bmj.com/content/earl...

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Webinar Series promotional graphic from EASD Early Career Academy. It lists: Date - 5 March 2026, 16:30 CET; Guest - Prof. Amalia Gastaldelli, National Research Council, Italy; Topic - “Could we change the course of MASLD - what is available and what is in the pipeline?” The EASD logo appears at the bottom left and the website easd.org/academy at the bottom right.

Webinar Series promotional graphic from EASD Early Career Academy. It lists: Date - 5 March 2026, 16:30 CET; Guest - Prof. Amalia Gastaldelli, National Research Council, Italy; Topic - “Could we change the course of MASLD - what is available and what is in the pipeline?” The EASD logo appears at the bottom left and the website easd.org/academy at the bottom right.

🎥This week, our EASD Early Career Academy is hosting a #webinar w. Prof. Amy Gastaldelli, co-author of the @easlnews.bsky.social Guidance on the full steatotic #liverdisease trajectory on #MASLD: treatments & what's next.

📅 5 March 2026 |🕛 16:30 CET

👉 Register now: us06web.zoom.us/webinar/regi...

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#microbiome #MASLD #health #SDGs

The neonicotinoid pesticide nitenpyram

damages the intestinal mucosa,

disturbs intestinal flora,

and increases Desulfovibrio gut microbiota.

Excessive H2S produced by Desulfovibrio
causes non-alcoholic steatohepatitis.
.
www.sciencedirect.com/science/arti...

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Honoured to receive the 🏅 Best Poster Presentation award 🏅at the #EASL #SLDSummit 2026 in Budapest 🇭🇺
A great opportunity to present and discuss data on platelet behaviour in #MASLD within an international scientific setting. Many thanks to all collaborators! 🙌

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Presented data from my study at the #EASL #SLDSummit 2026 in Budapest 🇭🇺
I shared insights on #platelet activation and function 🧪 across different stages of #MASLD

A valuable opportunity for discussion and scientific exchange ✨️

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Biomarker Liver Fibrosis

Indian #T2DM + #MASLD cohort n=789

FIB-4 & NAFLD Fibrosis Score performed poorly (sensitivity ~22%) vs FibroScan/Vibration-controlled transient elastography for advanced fibrosis (LSM≥9.7 kPa)

#DiabetesMetabSyndr 2026
www.sciencedirect.com/science/arti...

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The evolving concept from Cardiovascular-kidney-metabolic syndrome to metabolic associated liver-cardiovascular-kidney syndrome: insights from endocrinology Given the association of MASLD with cardiovascular, renal, and endocrine metabolic disorders, should cardiovascular-kidney-metabolic syndrome evolve to metabolic-associated…

Given the association of #MASLD with cardiovascular, renal, and endocrine metabolic disorders, should cardiovascular-kidney-metabolic syndrome evolve to metabolic-associated liver-cardiovascular-kidney syndrome?

👉 buff.ly/BfSXQvW

#EndoSky #MedSky

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#MASLD increases #PDAC risk & #livermetastasis by creating an #immunosuppressive niche driven by the MIF–CD44 axis, which enhances PDAC cell migration, stemness, and adhesion, while MIF inhibition reduces #metastasis, highlighting a targetable pathway.

#STTT: doi.org/10.1038/s413...

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Info about MASLD: Metabolic dysfunction-associated steatotic liver disease involves fat accumulation in the liver, which may cause liver inflammation. Obesity and type 2 diabetes are the main risk factors.

Info about MASLD: Metabolic dysfunction-associated steatotic liver disease involves fat accumulation in the liver, which may cause liver inflammation. Obesity and type 2 diabetes are the main risk factors.

Metabolic dysfunction–associated steatotic liver disease (#MASLD) involves accumulation of fat in the liver and may progress to liver inflammation and scarring (#fibrosis).

Learn more in this JAMA Patient Page: ja.ma/4tTZrtD

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🔥HOT TOPIC in #LiverTransplantation

This clinical trial shows that a structured, supervised exercise program significantly improves brain blood flow & cognitive function in patients with #MASLD, revealing powerful benefits that extend well beyond the #liver.

📙Full study: https://bit.ly/3NVFMZX

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EASD Early Career Academy Webinar Series promotional graphic. Date: 5 March 2026, 16:30 CET. Guest: Prof. Amalia Gastaldelli, National Research Council, Italy. Topic: Could we change the course of MASLD - what is available and what is in the pipeline? EASD Early Career Academy logo bottom left, easd.org/academy bottom right.

EASD Early Career Academy Webinar Series promotional graphic. Date: 5 March 2026, 16:30 CET. Guest: Prof. Amalia Gastaldelli, National Research Council, Italy. Topic: Could we change the course of MASLD - what is available and what is in the pipeline? EASD Early Career Academy logo bottom left, easd.org/academy bottom right.

📢 How much can we change the course of #MASLD?

The EASD #EarlyCareer Academy is hosting Prof. Amalia Gastaldelli for a new #webinar covering the science behind the #disease, where treatments stand & what's in the pipeline.

📅 5 March 2026 | 🕛 16:30 CET

🔗👉 Register: us06web.zoom.us/webinar/regi...

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Wee1-AS, a #lncRNA, protects against #MASLD by repressing #Wee1 and stabilizing #CYCLINB1 to activate CDK1-driven mitochondrial #FattyAcidOxidation, while WEE1 inhibition or the human homolog LNC106435.1 similarly improves mitochondrial function.

#STTT: doi.org/10.1038/s413...

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Un estudio internacional liderado por el CiMUS de la USC identifica que la pérdida de una enzima metabólica clave favorece la fibrosis hepática | CiMUS

Más info: cimus.usc.gal/es/noticias/...

#RedCIGUS #FondosEuropeos @usc.gal #InvestigaciónBiomédica #Transferencia #fibrosishepática #MASLD

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El 70% de las personas con diabetes tipo 2 tienen hígado graso (MASLD) — y casi nadie lo sabe. Explico qué es, cómo progresa en silencio y cómo detectarlo con un análisis rutinario. 🔗 🔗 pormeracuriosidad.com/higado-graso #MASLD #DiabetesT2

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Serpina3c mitigates prenatal prednisone exposure-induced #MASLD susceptibility in offspring by modulating hepatic lipid metabolism & inflammatory pathways, highlighting it as a #TherapeuticTarget to reverse adverse #MetabolicProgramming. #Medsky

#OpenAccess: doi.org/10.1038/s413...

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✍️ “When the liver fails, the brain does not escape the consequences,” shares Dr Anna Hadjihambi (@KingsCollegeLon). She & her lab are researching how #MASLD affects the brain & the #Ageing process. Read the blog to learn more 🔗 buff.ly/9ctxYSk #LiverDisease

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酒を飲まない人も危険な「脂肪肝」、放置すればがんや脳梗塞のリスク、記者が「痛くない」最新技術の検査受けてみた | JBpress (ジェイビープレス) 「ごん、お前だったのか。いつも栗をくれたのは」 新美南吉作『ごん狐』のラストシーンで兵十がつぶやく言葉は、黙々と貢献してきた存在がいなくなって、初めてそのありがたさを痛感するという「(1/5)

脂肪肝って、フォアグラなの?フォアグラが悪化するとどうなるのか…筆者が〈MRエラストグラフィ〉で肝臓を直視しました!

体を…いや腹を張っての取材です😅

#脂肪肝 #MRI #MASLD #ALD #MASH

jbpress.ismedia.jp/articles/-/9...

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Metabolic dysfunction-associated steatotic liver disease: heterogeneous pathomechanisms and effectiveness of metabolism-based treatment The global epidemic of metabolic dysfunction-associated steatotic liver disease (MASLD) is increasing worldwide. People with MASLD can progress to cirrhosis and hepatocellular carcinoma and are at inc...

A progressive subset of #MASLD, metabolic dysfunction-associated steatohepatitis (MASH), poses an immense and growing clinical and economic burden worldwide because of its risk of progression to advanced fibrosis, cirrhosis, and hepatocellular carcinoma www.thelancet.com/journals/lan...
#OpenAccess

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Variedad de alimentos: pescado, pimientos, tomate, champiñones, aceite, legumbres, queso, pan y frutos secos.

Variedad de alimentos: pescado, pimientos, tomate, champiñones, aceite, legumbres, queso, pan y frutos secos.

Se acabó el Carnaval. Tu hígado pide descanso.

El hígado graso no alcohólico afecta al 30-38% de adultos. La mayoría no lo sabe.

Y es reversible.

https://comerbeber.com/dieta-masld

#salud #nutrición #HigadoGraso #MASLD

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