A #clinical #SARS-CoV-2 #Mpro #inhibitor blocks replication of multiple #enteroviruses and confers oral in vivo protection in animal models, etidiohnew.blogspot.com/2026/03/a-cl...
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#MPro
Latest posts tagged with #MPro on Bluesky
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Seminário Público Economia Sustentável: Pagamento por Serviço Ambiental (PSA) e Crédito de Carbono - Soluções Ambientais que Geram Valor Social e Econômico: www.youtube.com/watch?v=ifU0....
Foi em 23/10/2025 #MPRO: pge.ro.gov.br/2025/10/10/s..., empro.mpro.mp.br/Acoes/160.
... mitigação climática...
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Ex-funcionária é condenada por desviar R$ 70 mil de escritório de advocacia em Ariquemes - open.substack.com/pub/painelpo... #PainelPolitico #JustiçaRondônia #Ariquemes #Estelionato #MPRO #OABRondônia #ÉticaNaAdvocacia #CrimesFinanceiros
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💥 Smarter warheads against SARS-CoV-2?
With #ISIDORe support, Di Micco’s team (Salerno) used crystallography to validate a novel covalent Mpro inhibitor—active across variants & easier to synthesize.
Next: bioassays, tox profiling & intranasal delivery.
#ISIDORe #Mpro #Antivirals
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💥 Smarter warheads against SARS-CoV-2?
With ISIDORe support, Di Micco’s team (Salerno) used crystallography to validate a novel covalent Mpro inhibitor—active across variants & easier to synthesize.
Next: bioassays, tox profiling & intranasal delivery.
#ISIDORe #Mpro #Antivirals
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TJ extingue ação contra Ivo Cassol; ex-governador fica mais perto de disputar eleições em 2026 - open.substack.com/pub/painelpo... #PainelPolitico #JustiçaRondônia #ImprobidadeAdministrativa #IvoCassol #MPRO #AcordoJudicial #TribunaldeJustiça
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Ex-prefeito de Porto Velho é condenado a 20 anos por estupro de vulnerável open.substack.com/pub/painelpo... #PainelPolítico #JustiçaRondônia #PortoVelho #CarlinhosCamurça #EstuproDeVulnerável #MPRO #DireitoPenal
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Meet An #MPro ("meditation professional"): Lisa Rambaldo, PsyD
Lisa joining the U.S. Veterans Administration in 2012 and has since dedicated herself to teaching #Mindfulness to Veterans and to the staff who provide their care. #meditation
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We’ve mentioned Australian MPro Joh Jarvis in previous newsletters…. Yet, we’re still pleased to see her get even more coverage for her work at the infamous Rikers Island prison. #meditation #mindfulness #mprofessional #mpro
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Take a moment to meet an #MPro (i.e. a "meditation professional")...
Ms. Sophie Kaufman, is leading the launch of a Mindfulness Community at Pace University, aimed at fostering connection, collaboration, and #wellbeing through #mindfulness. #meditation #mprofessional
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George Mumford, one of the top Meditation Professionals in the field, was recently invited to speak at #Youngstown State University. #meditation #mindfulness #mpro #mprofessional #georgemumford
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Meet An #MPro ("meditation professional"): Lisa Rambaldo, PsyD
Lisa joining the U.S. Veterans Administration in 2012 and has since dedicated herself to teaching #Mindfulness to Veterans and to the staff who provide their care. #meditation
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This week’s newsletter is now available to read for free on Substack.
This week’s topics include: #soundhealing #worldsoundhealingday #headspace #mpro
Pls like this post if anything we covered resonated with you..!
#meditation #mindfulness
meditationpronews.substack.com/p/top-medita...
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MPRO deflagra operação na Câmara de Ariquemes; presidente é um dos alvos - open.substack.com/pub/painelpo... #ariquemes #rondonia #mpro #noticias #painelpolitico
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Preso na "Dionísio", Júnior Lopes deve negociar delação premiada com MP - open.substack.com/pub/painelpo... #noticias #dionisio #sejucel #mpro #painelpolitico
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Segunda fase da 'Dionísio' em Rondônia prende preventivamente ex-secretário de Esportes Júnior Lopes - open.substack.com/pub/painelpo... #rondonia #noticias #dioniosio #mpro #sejucel #painelpolitico
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Great Sasuke doing cool guy shit. #MPRO 🤼
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Veja a íntegra da denúncia do TCE que culminou com a Operação Dionísio, deflagrada pelo MP em Rondônia - open.substack.com/pub/painelpo... #noticias #tce-ro #mpro #dionisio #painelpolitico
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MPRO deflagra operação que investiga desvios de recursos da Expovel; secretário da Sejucel foi afastado - open.substack.com/pub/painelpo... #noticias #mpro #painelpolitico
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Mulher que usava crianças para vender doces nas ruas de Porto Velho é presa por explorar trabalho infantil - open.substack.com/pub/painelpo... #mpro #trabalhoinfantil #noticias #painelpolitico
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We use our method on SARS-CoV-2 main protease #MPro and both #active site and potential #allosteric #sites are classified as #Cluster1 sites, demonstrating that these RSA-based Cluster labels can #recapitulate known #functional protein regions such as active or allosteric sites
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#MedSky🧪 #IDSky #Drugdevelopment interesting study on An oral non-covalent non-peptidic inhibitor of #SARSCoV2 #Mpro ameliorates #viralreplication & pathogenesis in vivo
www.cell.com/cell-reports...
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#Olgotrelvir, a dual inhibitor of #SARSCoV2 #Mpro and cathepsin L, as a standalone antiviral oral intervention candidate for #COVID19
www.cell.com/med/fulltext...
Ref pubmed.ncbi.nlm.nih.gov/38181791/
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#MedSky🧪 #IDSky
Does #olgotrelvir ( an oral #antiviral with dual mechanisms of action targeting severe #COVID main protease (i.e. #Mpro) & human #cathepsin L. It has potential to serve as a single-agent treatment For #COVID19
evidence.nejm.org/doi/full/10.... ) work against #SARSCoV2 ?
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MedSky🧪 #IDSky #Viralimmunology #Chemistry Where are we with #SARSCoV2 #Mpro inhibitors ? The main protease (Mpro) enzyme www.sciencedirect.com/topics/pharm... has an imperative function in disease progression www.sciencedirect.com/topics/pharm... & the life cycle of #SARSCoV2 🦠
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