🐟 Studying #zebrafish pituitary development, researchers show that ASO-induced suppression of gene #splicing leads to the dysregulation of intronic primary #microRNAs.
www.nature.com/articles/s42...
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#MicroRNAs
Latest posts tagged with #MicroRNAs on Bluesky
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Posts tagged #MicroRNAs
This review shows how #microRNAs regulate #AdiposeTissueFibrosis via key pathways, while miRNA-engineered stem-cell #secretomes enable targeted delivery and stronger #antifibrotic effects, offering strategies for metabolic fibrosis treatment.
#OpenAccess: doi.org/10.1016/j.ge...
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This review shows how dysregulated #SUMOylation drives #glioblastoma aggressiveness via #cellcycle, AKT, #microRNAs & #DNARepair, highlighting Ubc9/SAE1 as targets and SUMO inhibitors as promising strategies against proliferation & resistance.
#OpenAccess: doi.org/10.1016/j.ge...
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Using functional assays and mutant viruses, the authors demonstrate that these #microRNAs directly target interferon receptors and core JAK/STAT signaling components, reducing antiviral gene activation during both early and latent infection.
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p62 sorts Lupus La and selected #microRNAs into #BreastCancer-derived #exosomes, say Jordan Matthew Ngo, Randy Schekman and colleagues @ucberkeleyofficial.bsky.social: rupress.org/jcb/article/...
#Trafficking #Biochemistry
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Explore microRNAs, siRNAs, and piRNAs with Novogene’s small RNA sequencing (sRNA-Seq) services. Gain precise insights into their regulatory roles and functions.
Learn more: https://bit.ly/3P1VkbT
#SmallRNA #sRNASequencing #MicroRNAs #GeneRegulation #Transcriptomics #GenomicsInnovation
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Investigation of #masseter #muscle in #microphthalmia mice (with Mitf mutation and masticatory dysfunction) shows increased myocyte #apoptosis and #fibrosis, reduced masseter muscle mass and low expression of #microRNAs needed for #skeletal muscle development
doi.org/10.14814/phy...
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Investigating miR-16-5p: The Tumor Suppressor That Influences Cell Cycle Genes in Colorectal Cancer
#JBPE #MicroRNAs #CellCycle #Radiation-Sensitizing #AgentsColorectalCancer
DOI: doi.org/10.31661/jbp...
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Higher miR-33a & miR-122 levels in T2DM patients with metabolic syndrome correlate with lipid metabolism issues. #MicroRNAs #MetabolicSyndrome
www.rimpacts.com/rd/p?c=10126...
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🧠 In #ParkinsonsDisease, altered #microRNAs — including miR-107, miR-153, miR-205 & miR-34 — regulate key genes (SNCA, LRRK2, PINK1, PARK2) that control oxidative stress, mitochondrial health & apoptosis.
Their presence in biofluids offers hope for early, non-invasive #biomarkers
#miRNA#Neuroscience
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#FruitRes
MicroRNAs in peach fruit development identified through small RNA sequencing. Study explores miRNA regulatory networks and auxin signaling. 🍑
Details: maxapress.com/article/doi/10.48130/fru...
#Peach #MicroRNAs
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Exploring how #microRNAs can transform #NeurodegenerativeDiseases care 🧬
Early #diagnosis | Novel #therapies
🔗 rdcu.be/eJZtt
@springernature.com @neurosciencenews.bsky.social
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Infographic showing how altered microRNA expression contributes to Alzheimer’s pathology — promoting amyloid-beta plaques, neurofibrillary tangles, neuroinflammation, and neuronal apoptosis in the hippocampus
In #Alzheimer dysregulated #microRNAs influence key #pathological features —
🧩 #Aβ plaque buildup
🧩 #Tau #hyperphosphorylation & neurofibrillary tangles
🧩 #Neuroinflammation & apoptosis in the hippocampus
Understanding these miRNA shifts opens doors to early diagnosis & targeted therapies.
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Explore microRNAs, siRNAs, and piRNAs with Novogene’s small RNA sequencing (sRNA-Seq) services. Gain precise insights into their regulatory roles and functions.
Learn more: bit.ly/3P1VkbT
#SmallRNA #sRNASequencing #MicroRNAs #GeneRegulation #Transcriptomics #GenomicsInnovation
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#Medsky🧪 #IDsky #immunosky #publichealth #MicroRNAs their significance in #longCOVID
#MicroRNAs (miRNAs) are emerging as crucial regulators of gene expression, playing a vital role in various biological processes such as the immune response, inflammation, and tissue repair.
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Plant microRNA maturation and function. #microRNAs @natrevmcb.nature.com
www.nature.com/articles/s41...
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ROC curve for the diagnostic accuracy of miRNA in DLBCL.
#MicroRNAs, especially miR-21 and miR-155, show promise as diagnostic and prognostic #biomarkers in diffuse large B-cell lymphoma (DLBCL), with strong accuracy and survival prediction. #DLBCL #Oncology onlinelibrary.wiley.com/doi/10.1002/...
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Honored to be at #PhysiologyofObesity2025 @uniofnottingham.bsky.social representing @mark-christian-lab.bsky.social. Sharing our work on #BrownFat -enriched #microRNAs in #lipodystrophy and #obesity. Poster up today, come by!
#SHIMR_NTU @physoc.bsky.social @jhobbs22.bsky.social @ntumeta.bsky.social
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Published in Horticulture Research, a research team from Gansu Agricultural University has unveiled new insights into potato dormancy regulation through microRNA activity.
#Potato #microRNAs
Details: doi.org/10.1093/hr/u...
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Explore microRNAs, siRNAs, and piRNAs with Novogene’s small RNA sequencing (sRNA-Seq) services. Gain precise insights into their regulatory roles and functions.
Learn more: bit.ly/3P1VkbT
#SmallRNA #sRNASequencing #MicroRNAs #GeneRegulation #Transcriptomics #GenomicsInnovation
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🕵️♀️ Get to know malaria researcher and Infect-Net member Nahla Galal Metwally @nahlagalalmetwally.bsky.social from BNITM!
She will introduce you to #microRNAs and their role in disease development of #malaria infections.
🗓️ 03.06.25, 🕓 4pm
#bookascientist 👇
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Explore microRNAs, siRNAs, and piRNAs with Novogene’s small RNA sequencing (sRNA-Seq) services. Gain precise insights into their regulatory roles and functions.
Learn more: bit.ly/3P1VkbT
#SmallRNA #sRNASequencing #MicroRNAs #GeneRegulation #Transcriptomics #GenomicsInnovation
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🧬 How do #microRNAs regulate #metabolism and #immunity? Oliveto et al. discuss their role for #glucose and #lipids, #Bcells and #Tcells – and explore #AI in #miRNA research! #RNA
➡️ doi.org/10.1002/1873-3468.70039
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Massachusetts General Hospital Founding Member, Mass General Brigham Please join us for the Ruvkun Nob73 Symposium Honoring Gary Ruvkun's Nobel Prize in Physiology or Medicine Tuesday, April 10 9 a.m.- 6:30 p.m. Third floor, large seminar room 3110 Simches Research Building 185 Cambridge Street Massachusetts General Hospital (MGH) and Harvard Medical School investigator Gary Ruvkun, PhD, has been named Physiology or Medicine for his role in the discovery of microRNA and its role in post-transcriptional gene regulation
Gary Ruvkun presenting history of miRNA discovery.
9:00 am - 9:15 am Coffee Session A 9:15 am to 11:00 am - Moderator: Sylvia Fischer 9:15-9:20 Diane Sacchetti 9:20-9:45 Gary Ruvkun 9:45-9:55 David Greenstein 9:55-10:05 Heidi Tissenbaum 10:05-10:15 Kotaro Kimura 10:15-10:25 Mike Finney 10:25-10:30 Ann Sluder 10:30-10:40 Tom Barnes 10:40-10:50 Christopher Carr 10:50-10:55 Angel Mojarro 10:55-11:00 Thomas Isenbarger Ruvkun Nob73 Schedule revised Mon Apr 8 4 pm Break 11:00 to 11:15 am Session B 11:15-11:25 11:25-11:35 11:35-11:45 11:45-11:55 11:55-12:05 12:05-12:15 12:15-12:20 12:20-12:30 12:30-12:40 12:40-12:50 12:50-1:00 11:15 am to 1:00 pm - Moderator: David Greenstein Amy Pasquinelli Frank Slack Eric Lai John Kim Himani Galagali Scott Kennedy Duo Wang, Sylvia Fischer Tai Montgomery Carolyn Phillips Hafiz Mohd Rothi Lunch 1:00 pm to 2:00 pm 2-00-2:10C 2:00 Kat Ashram - Moderator: Carolyn Phillips 2:00-2:10 2:10-2:20 Sylvia Le 2:20-2:30 leng Wan 2:30-2:40 Sean Curran 2:40-2:50 Eyleen O'Rourke 2:50-3:00 Patrick Hu 3:00-3:10 3:10-3:20 Buck Samuel Natasha Kirienk 3:20-3:30 Alex Soukas 3:30-3:35 Sascha Russel 3:35-3:40 3:40-3:45 Amaramanath Govindan 3:45-3:50 Dave Shore 3:50-3:55 Maria Armakola Break 3:55 pm to 4:15 pm 4:45-4:55 4:55-5:05 5:05-5:15 5: 15-5:25 5:25-5:35 5:35-5:45 5:45-5:55 5:55-6:00 6:00-6:05 Nic Lehrbach Josh Meisel Kurt Warhoff Ilya Ruvinsky Yuval Tabach Kai Mao Andy Samuelson Ashwin Seetharaman
Had an amazing and inspiring time at #Garypalooza celebration at MGH this week. Was so great to meet many current and catch up with former Ruvkunites. Such an incredible broad legacy of impact and innovation in many fields #Celegans #microRNAs and beyond.
#NobelPrize #academicsky 🧪🦠🧬 🪱
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This review from our Italian partners explores the growing body of evidence surrounding circulating #microRNAs and their potential role as #biomarkers in #Alzheimers disease and #frontotemporaldementia, additional info: myriad-jpnd.com
www.mdpi.com/3256966
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Check out this SPLASH! Milk Science Update: One study identified over 2,000 #microRNAs in #breastmilk, and found that specific microRNAs are active at different times across #lactation! #science #milk www.milkgenomics.org?splash=micro... @ www.annapetherick.com
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MicroRNAs unveiled: Nobel recognition of a revolutionary gene regulation mechanism
doi.org/10.1016/j.hl...
#MicroRNAs #miRNAs #academics #AcademicChatter #AcademicTwitter
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Diagram illustrating the role of miRNAs in the rhizosphere. Whole plants are shown growing in situ with annotations to indicate the role of miRNAs in pathogen resistance, nodule formation and abiotic stressors.
#MicroRNAs play a crucial role in #plant communication within the #rhizosphere, shaping #growth, #development, and resilience to biotic and abiotic stresses. Learn more in a new #OpenAccess JIPB review by Fahad et al.!
doi.org/10.1111/jipb...
#PlantScience #roots 🔓
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