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Function ☕ Monday Insights: Congrats 🎖️ to @edenmgallegos et al., for their #APSselect paper evaluating the effects of ethanol, sugars, and fats on hepatocyte #LipidMetabolism, #OxidativeStress, and #MitochondrialFunction in a spheroid model. Read doi.org/10.1093/func... #MetALD

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Partial restoration of mitochondrial dysfunction by AAV-Ant1 protects from dilated cardiomyopathy in Ant1-/- plus mtDNA mutant mice - Nature Communications Patients with primary mitochondrial disease manifesting cardiomyopathy are twice as likely to die compared to those without cardiomyopathy. Here, the authors show that a modest increase in cardiac mit...

#TargetedGeneTherapy for partial restoration of #MitochondrialFunction and protection against #DilatedCardiomyopathy www.nature.com/articles/s41... #MitochondrialCardiomyopathy #CardiacFunction #PGC1α #TranslationalScience

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Age Doesn't Define Your Energy - Chris Masterjohn with Joe Rogan

#control #mitochondrialfunction

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Bezafibrate improves mitochondrial function, blood-brain barrier integrity, and social deficits in models of 22q11.2 deletion syndrome Pharmacological recovery of mitochondrial function improves blood-brain barrier function and cognition in 22q11.2 deletion syndrome, a risk factor for schizophrenia.

Characterizing the role of #Mitochondria in the #BloodBrainBarrier (BBB) & how impaired #MitochondrialFunction within the BBB relates to disease expression doi.org/10.1126/scit... #Neuroscience #TranslationalScience

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August 26 Seminar
“Metabolic and physiological implications of flexibility in the electron transport chain”  by Jessica Spinelli PhD, Assistant Professor, Program in Molecular Medicine
UMass Chan Medical School
Host: Tigist Tamir 8/26/2025 @11AM in 1131 Bioinf bldg.

August 26 Seminar “Metabolic and physiological implications of flexibility in the electron transport chain” by Jessica Spinelli PhD, Assistant Professor, Program in Molecular Medicine UMass Chan Medical School Host: Tigist Tamir 8/26/2025 @11AM in 1131 Bioinf bldg.

Seminar Aug. 26 11 AM
“Metabolic and physiological implications of flexibility in the electron transport chain” - Jessica Spinelli PhD, Asst. Professor, Program in Molecular Med., UMass Chan Medical School, Host: Dr. Tamir, Venue: 1131 Bioinf bldg. #MitochondrialFunction #ETC #MetabolicFlexibility

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Human IRAK kinases differentially alter metabolic regulation and mitochondrial function in Saccharomyces cerevisiae
Cid, V. J., del Val, E. et al.
Paper
Details
#IRAKKinases #MitochondrialFunction #YeastMetabolism

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Hemoglobin alpha regulates T-lymphocyte activation and mitochondrial function
Case, A. J., Griffin, B. L. et al.
Paper
Details
#HemoglobinAlpha #TCellActivation #MitochondrialFunction

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