#CardiacFunction

@genesndiseases.bsky.social

2 months ago

This review describes the relationship between #mtDNA integrity and #CardiacFunction, the associated regulatory pathways and the mechanisms driving #MitochondrialDysfunction and #Ischemia/#Reperfusion-induced cardiomyocyte injury. #medsky

#OpenAccess: doi.org/10.1016/j.ge...

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UPENN_ITMAT

@itmat.bsky.social

2 months ago

Partial restoration of mitochondrial dysfunction by AAV-Ant1 protects from dilated cardiomyopathy in Ant1-/- plus mtDNA mutant mice - Nature Communications Patients with primary mitochondrial disease manifesting cardiomyopathy are twice as likely to die compared to those without cardiomyopathy. Here, the authors show that a modest increase in cardiac mit...

#TargetedGeneTherapy for partial restoration of #MitochondrialFunction and protection against #DilatedCardiomyopathy www.nature.com/articles/s41... #MitochondrialCardiomyopathy #CardiacFunction #PGC1α #TranslationalScience

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BioNews Central

@bionewscentral.com

7 months ago

New mRNA-based therapy that shows promise in heart regeneration after heart attack – BioNews Central New research demonstrates that delivering the gene PSAT1 via synthetic modified messenger RNA (modRNA) can stimulate heart muscle repair and improve cardiac function after a heart attack, marking significant progress in regenerative treatments for is

New research demonstrates that delivering the #PSAT1gene via synthetic modified #messengerRNA (#modRNA) can stimulate #HeartRepair and improve #CardiacFunction after a #HeartAttack, marking significant progress in #RegenerativeTreatments for #IschemicHeartDisease.
#HeartDisease #CardiacRegeneration

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The Physiological Society of Japan 日本生理学会

@physiologyjapan.bsky.social

8 months ago

🫀 Just published online in JPS❣️
"Xanthine oxidase inhibitor allopurinol preserves cardiac function after experimental malocclusion induced by occlusal disharmony in mice"
-- Takao Mitsubayashi et al.
🔗 [https://doi.org/10.1016/j.jphyss.2025.100029]
#CardiacFunction #Allopurinol #Malocclusion

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Genes & Diseases Journal

@genesndiseases.bsky.social

9 months ago

HIIT Boosts Heart Health at the Molecular Level
High-intensity interval training elevates meteorin-like protein, improving cardiac function via the AMPK/HDAC4 signaling axis. doi.org/10.1016/j.ge...
#ExerciseScience #HIIT #CardiacFunction #MolecularPathways

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Physiological Reports

@physrep.bsky.social

10 months ago

Investigation of roles of #PDGF and #TGFβ signaling in right ventricular #fibrosis, using the dual inhibitor, #Tranilast, reports reduced RV #hypertrophy and improved diastolic relaxation, implicating both growth factors as relevant targets.
doi.org/10.14814/phy...
#Cardiovascular #CardiacFunction

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Inserm U1034 - Biology of Cardiovascular Diseases

@insermu1034.bsky.social

10 months ago

Partial Mural Cell Ablation Disrupts Coronary Vasculature Integrity and Induces Systolic Dysfunction | Journal of the American Heart Association

Repost
[Publication] Happy to share Dr Renault and
Dr Cornuault's new publication in which they demonstrated that #cardiacpericytes are essential for maintaining #cardiacfunction, directly modulating cardiomyocyte properties and preventing cardiac inflammation. www.ahajournals.org/doi/full/10....

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@healthwellness.bsky.social

1 year ago

Heart health: Drinking ketones may help improve function People with type 2 diabetes who were given ketones before exercise had increased cardiac output, stroke volume, and peripheral muscle oxygenation, which are all indicators of improved heart function.

❤️ Heart health: Drinking ketones may help improve function

People with type 2 diabetes who were given ketones before exercise had increased cardiac output, stroke volume, and peripheral muscle oxygenation, which are all indicators of improved heart...

#HeartHealth #KetonesBenefits #CardiacFunction

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