#NRTIs

Latest posts tagged with #NRTIs on Bluesky

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Posts tagged #NRTIs

Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

2 months ago

#LINE1 upregulation is identified as a driver of #VascularCalcification; silencing LINE1 or using #NRTIs suppresses cGAS‑STING signaling and mitigates VC—highlighting LINE1 inhibition and NRTIs as promising therapeutic strategies.

#OpenAccess in #STTT: doi.org/10.1038/s413...

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Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

5 months ago

#LINE1 drives #VascularCalcification (VC) via cGAS-STING–mediated #inflammation, and silencing LINE1 or treating with #NRTIs suppresses VSMC osteogenic reprogramming, reduces VC in mice, and lowers VC incidence in humans. #medsky

#OpenAccess in #STTT: doi.org/10.1038/s413...

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