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#NowWatching: The Secret of NIMH (1982)

Directed by Don Bluth @donbluth.bsky.social

Starring Elizabeth Hartman, Peter Strauss, Derek Jacobi, Dom DeLuise, John Carradine, Shannon Doherty & Wil Wheaton

#Movies #80s #Animation #FilmSky #Cinema #Scifi #Nostalgia #Mice #DonBluth #NIMH #MovieSky

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#AlbumReview: #NIMH Nine Years of Decadence via #FlutteringDragonRecords by #Pegah

The album title, which refers to this period of time, points to a perceived decline in culture, humanity, and morality...

shorturl.at/ZTM4k

#WeAreBlessedAltarZine
#TheZineSupportingTheUnderground

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We sincerely thank #NIMH #NIGMS & @lieberinstitute.bsky.social for supporting this work and are deeply grateful to the donors and their families, whose generosity made this research possible.

Again, we’re very excited to share this work with the community and look forward what comes next 🤩 (9/9)

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Two openings for a Staff Research Associate (Study Coordinator/Lab Manager) in the Brain & Body Lab and SAND Labs at UCLA with @jasilvers.bsky.social and @drbcallaghan.bsky.social working on different #NIMH #NIA funded research studies.

Apply here:
jobs.ucla.edu/jobs/9781
jobs.ucla.edu/jobs/9782

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We have followed this up on many levels-preprints coming soon. This one spent a long time cooking and I am grateful to my lab, the #NIMH, UVA and the Owens Foundation for funding support, and the reviewers for their time and critical insights 🙏

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Guess who got into Blush Blush again...

[ #lettersillust #blushblush #BL #volks #nimh ]

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Jeremy is like a himbo (?) #retro #cartoon #secretofnimh #nimh

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Une telle #mégalomanie ... il faudrait investiguer davantage quitte à se faire interdire d'entrée aux #USA !!!
@whashingtonpost.bsky.social @nytimes.com @bloomberg.com @en.afp.com @reuters.com @apnews.com @lepoint.fr @mariannelemag.bsky.social
#MDP #DSM #DSM5 #NIMH #CIM #OMS

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Dr. Provenza receives a new $3.7 million R01 Award from the National Institutes of Health and National Institute of Mental Health for her project Neurophysiological investigation of the approach-avoidance axis in OCD: applications to neuromodulation.

Dr. Provenza receives a new $3.7 million R01 Award from the National Institutes of Health and National Institute of Mental Health for her project Neurophysiological investigation of the approach-avoidance axis in OCD: applications to neuromodulation.

Day 8️⃣: August 📅

Dr. @nicoleprovenza.bsky.social received a $3.7m R01 award from the #NIH and #NIMH to study approach-avoidance behaviors after #DBS for #OCD 🧠

#BCMNeurosurgery | #DeepBrainStimulation | #ObsessiveCompulsiveDisorder | #Neurosurgery | #Research

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#Pegah 2025 Top 10 (Part 2)
Our writer Pegah wrote some lines about their Top 10
https://2cm.es/1glQF
#Nimh #Onasander

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A white battery charger containing two orange batteries on a little shelf connected to a black powerbank with a black USB cable

A white battery charger containing two orange batteries on a little shelf connected to a black powerbank with a black USB cable

Today on Mythconfirms: How many Ni-MH batteries can i charge with my 45000mAh powerbank, and how long can it keep you charged for a doomsday scenario
#powerbank #doomsdayprep

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Mother hushed child
Fear growing as the rain falls
Amulet gives strength

#haikufeels #haiku #poetry #prompt #nimh

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Overall, the study suggests a strong coupling between noradrenergic signaling and movement, but a limited causal role of LC-NE in promoting behavioral arousal.

Many thanks to Michael and co-authors Akshay Rana, Esther Li, Bailey Wells, Sayaka Kenmochi, Myesa Travis. #NIDA #NIMH #FAER

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Escape from the National Institute of Mental Health
14" x 11"
Acrylic on canvas
#art #painting #contemporaryart #fantasyart #rat #mouse #nimh #klopfensteinstudio

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Preview
A Hassle-Free Battery Charger Lithium-ion batteries’ ability to deliver a lot of power from a small package have made them the go-to for makers and manufacturers alike. It’s not unusual now to find, say, microcontroller boards with integrated Li-ion chargers. Lithium-ion is so popular, in fact, that it’s easy to forget that other battery technologies exist, even when they’re a better fit. These worthy alternatives include removable rechargeable nickel–metal hydride batteries. While NiMH cells can’t be recharged as many times as lithium-ion cells can and don’t offer the same power density, they’re cheaper and also safer. No need to ship them in boxes emblazoned with fire warning labels. The fact that NiMH cells deliver lower voltages than lithium has become less of an issue as the voltage demands of integrated circuits have fallen, with 3.3-volt and 1.8-V chips rapidly displacing the ubiquitous 5-V standard of yesteryear. ## How to Make NiMH Easier to Manage A handful of 3D-printed parts [bottom], a servo and screen [middle] and a single printed circuit board [top] are all that’s needed for the Spinc charger. James Provost But it’s also true that recharging removable batteries can be a pain: You have to load them into a charger, which typically holds no more than four batteries at a time, and take care to put them in the right way. Otherwise you get no charging at best and irreversible damage to the cell and even overheating at worst. To ease this pain point, I created the Spinc, a DIY device that charges up to seven NiMH AA batteries at a time and automatically figures out the polarity of each cell before charging it; when finished, it drops the batteries into a hopper. You can check on the charging status via a display that doubles as a clock. In my day job, I work on industrial vehicles as an EE in a midsize German company. But I came to this project due to a personal interest in low-power electronics and after a fruitless attempt to harvest the last dregs of power from some nonrechargeable batteries. That failure—in a nutshell, my design needed a buffer battery that had to be recharged, which defeated the whole purpose of the project—got me thinking about rechargeable cells. The hardest part of creating the Spinc was a self-imposed challenge. I wanted the charger to be compact and intuitive to use. This meant spending a lot of time perfecting the mechanism that takes a battery from the top of the charger, places and holds it between two electrodes while charging, and then drops the battery out the bottom before resetting and grabbing the next cell. A lot of careful iterations later, I had a set of seven 3D-printer files to create the parts that assemble to form the case and mechanism of the Spinc. To that, you just need to add the display, servo motor, and a printed circuit board with all the remaining components, plus an infrared proximity sensor that detects when a battery has been inserted and is ready to be placed between the charging electrodes. ### To allow the battery to be charged regardless of which way it’s put into the charger, I used a classic H-bridge circuit, which is normally used to let DC motors run in either direction, with a few modifications that let it work at low voltages. I decided to use a dedicated integrated circuit to manage the actual charging, with thermistors to watch out for overheating. While I could have used a microcontroller and written my own software to monitor the battery, NiMH cells have a very flat charging curve, and it’s easy to overshoot the charging cycle. Using an IC saved me from a lot of testing, and also gave me the ability to use a fast-charging mode. However, it didn’t save me from some trial and error. The first charger IC I used was attractively compact at 2 by 2 millimeters. However, when I tried charging an AA battery, I discovered that the manufacturer assumed the end user would be charging two to four batteries at a time, all hooked up in series. Charging just a single battery meant the IC’s linear voltage regulator had to dissipate more heat than intended, and it quickly burned the chip out. I eventually found a somewhat larger (5.15 by 4.4 mm) charger IC that uses a switched-mode regulator and could handle the job. Finding that IC took a while, though, as the popularity of lithium batteries has reduced the availability of supporting components for NiMH. The charging curve of NiMH follows a slow curve, with the battery’s voltage showing a dip of just 2 millivolts when fully charged, which is easily overshot and could lead to cell damage.James Provost The charger IC is connected to an RP2040 microcontroller, which reports the battery status on an LCD display. The RP2040 is also responsible for monitoring the proximity sensor and driving the servo that controls the internal feed mechanism, as well as responding to the Spinc’s push-button controls, which let you set the clock and start charging the batteries. The entire device is powered via a USB-C socket. Most of the electronics are surface-mounted on a PCB that has a large center cutout to allow the batteries to pass through it. I designed the PCB in KiCad and had it fabricated by JLCPCB. To make it easier to fabricate the boards correctly, I didn’t try to specify 90-degree angles for the corners of the center cutout. Instead, I went with rounded corners, which are easier for the cutting tooling to follow. The result is a desktop charger that’s as convenient to use as possible. A full set of PCB schematics, bill of materials, 3D printer files, and firmware files are available from the project page on GitHub. I hope it helps ensure that whenever you need a freshly charged NiMH battery, there’s one right at hand!
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Personalized brain modeling of anesthetic effects to predict antidepressant response ShiNung Ching, Ben Julian Palanca, MD, PhD, look at brain dynamics, neural circuits as clues to alternative approaches

With a $1.2M grant from #NIMH, @washuengineers.bsky.social ShiNung Ching & @washumedicine.bsky.social Ben Palanca will use EEG brain wave patterns to develop personalized dosing strategies for anesthetic-based therapies for treatment-resistant depression.

engineering.washu.edu/news/2025/Pe...

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Original post on gts.skobk.in

Непросто было найти крону аккумулятор не на литии.

Не, я понимаю, что ёмкость больше. Я даже понимаю, что кому-то зарядка батареек через type-C может казаться удобной.

Но в гитару такие батарейки ставить банально нельзя - их преобразователи шумят.

#hardware #log #batteries #rechargable #LiIon […]

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The Mouse Utopia Experiments | Down the Rabbit Hole
The Mouse Utopia Experiments | Down the Rabbit Hole YouTube video by Fredrik Knudsen

The Mouse Utopia Experiments | Down the Rabbit Hole

youtube.com/watch?v=NgGL...
#NIMH

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Hello friends who have #NIMH grants... any one work through the startup of a #BESH (Basic Experimental Studies Involving Humans) classified project?

If so, could we chat?

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The Dutch Marine Brigade advances to #Driaredja on Java, Dutch East Indies(now #indonesia). A broad front extends from village to village, June 13, 1946. #nimh

#nederlandsindie #DeOost #politioneleacties #java #indonesië #sukarno #mohammedhatta #ww2 #KNIL #mariniers #marines

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APRIL 1945 | FRIESLAND | NETHERLANDS
In the Frisian countryside, evacuees from Zuid-Limburg are on their way home. On average a 200 mile journey.

#WWII #bevrijding #wo2 #friesland #zuidlimburg #provinciefriesland #provinciezuidlimburg
#vluchtelingen #nimh #vluchtelingenopvang #WW2

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A #Flail tank, designed to detonate mines, leaves a LCT during the landing at #Westkapelle, #Zeeland Province, The Netherlands on November 2, 1944.

Liberated ##Antwerp was to become the supply port for the Allied advance but first the Western Scheldt had to be breached.

#WW2 #nimh

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Original post on dice.camp

I finally ordered a new digital camera.

I ordered the Kodak PixPro FZ45. It's a 16 megapixel "point-and-shoot" digital camera with 4x optical zoom and the ability to record 1080p video at 30 fps. The Kodak brand is used under license, Kodak did not manufacture it.

A requirement for any new […]

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Rewatched Secret of NIMH for the first time in forever.

#SecretofNIMH #NIMH #mrsbrisby #furry #nsfw

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Scientist looking in microscope 
Photo: Getty Images

Scientist looking in microscope Photo: Getty Images

Physicians Committee Urges #NIMH to End Outdated Animal Testing Practices

#USA 🇺🇸 #AnimalTesting #USpoli #LabAnimals #AnimalResearch #AnimalCruelty #Animals #MentalHealthResearch #AnimalWelfare #Health #Science #AnimalRights #AnimalLaw

@pcrm.org

www.pcrm.org/news/good-sc...

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📣The National Institutes of Health (NIH) is accepting applications for Director of the National Institute of Mental Health (NIMH). Help us spread the word about this opportunity!

🔗Find more information here: hr.nih.gov/jobs/search/...

#jobopportunity #NIMH

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notice of award for an NIMH grant

notice of award for an NIMH grant

Over the moon to announce that I received the Notice of Award for my #NIMH K08!

This 5 year project will adapt a tool to help implementation and mental health organizations with strategic financial planning.

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Ferals have forsaken all bonds of critterdom, they have become blood thirsty creatures. #bramble #ttrpg #NIMH

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Mrs. Brisby from the Don Bluth film, The Secret of NIMH. Siting casually on a tree stump in the wilderness.

Mrs. Brisby from the Don Bluth film, The Secret of NIMH. Siting casually on a tree stump in the wilderness.

Was feeling a little Brisby today!
#secretofnimh #nimh #mrsbrisby #paws #mouse

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Post image Project Title:
Neurophysiological investigation of the approach-avoidance axis in OCD: applications to neuromodulation

Project Narrative:
Despite FDA approval for deep brain stimulation (DBS) for obsessive-compulsive disorder (OCD) in the form of a Humanitarian Device Exemption, this therapy remains underutilized and poorly understood. Based on the pathologically avoidant phenotype underlying OCD and the pro-approach behavior required to overcome fear-based avoidance, we conceptualize our study of the neurophysiological underpinnings of OCD by tracking behavior and ventral striatum neural activity along the approach-avoidance axis. Doing so would create a foundational understanding of the neurobehavioral effects of DBS that will generalize to other disorders characterized by dysregulation of behavior along the approach-avoidance axis.

Project Title: Neurophysiological investigation of the approach-avoidance axis in OCD: applications to neuromodulation Project Narrative: Despite FDA approval for deep brain stimulation (DBS) for obsessive-compulsive disorder (OCD) in the form of a Humanitarian Device Exemption, this therapy remains underutilized and poorly understood. Based on the pathologically avoidant phenotype underlying OCD and the pro-approach behavior required to overcome fear-based avoidance, we conceptualize our study of the neurophysiological underpinnings of OCD by tracking behavior and ventral striatum neural activity along the approach-avoidance axis. Doing so would create a foundational understanding of the neurobehavioral effects of DBS that will generalize to other disorders characterized by dysregulation of behavior along the approach-avoidance axis.

DBS and OCD:

Obsessive-compulsive disorder (OCD) has a lifetime prevalence of 2-3% and is a major cause of global disability. OCD is characterized by obsessions (i.e., unwanted intrusive thoughts) and compulsions (i.e., repetitive ritualistic behaviors), and exemplifies a pathologically avoidant phenotype where greater degrees of avoidance are associated with greater symptom severity and treatment resistance. In the 20-40% of OCD patients that are treatment refractory, deep brain stimulation (DBS) of the ventral capsule and ventral striatum (VC/VS) is an effective therapy that achieves significant benefit in 66% of patients. 

While VC/VS DBS does not acutely relieve OCD symptoms, DBS often produces a “pro-approach” response including an increase in talkativeness, a desire to engage in activities, extroversion, and affiliative behavior. Our central therapeutic hypothesis is that VC/VS DBS achieves eventual benefit in OCD by providing the “boost” in pro-approach behavior that allows individuals to overcome their pathological fear-based avoidance. Thus, we focus on the approach-avoidance axis as one of the critical neurobehavioral axes underlying the pathophysiology of OCD. Our overall goal is to develop a mechanistic understanding of DBS for OCD by rigorously investigating the relationship between clinical symptoms, behaviors (i.e., approachful vs. avoidant), and neurophysiology.

DBS and OCD: Obsessive-compulsive disorder (OCD) has a lifetime prevalence of 2-3% and is a major cause of global disability. OCD is characterized by obsessions (i.e., unwanted intrusive thoughts) and compulsions (i.e., repetitive ritualistic behaviors), and exemplifies a pathologically avoidant phenotype where greater degrees of avoidance are associated with greater symptom severity and treatment resistance. In the 20-40% of OCD patients that are treatment refractory, deep brain stimulation (DBS) of the ventral capsule and ventral striatum (VC/VS) is an effective therapy that achieves significant benefit in 66% of patients. While VC/VS DBS does not acutely relieve OCD symptoms, DBS often produces a “pro-approach” response including an increase in talkativeness, a desire to engage in activities, extroversion, and affiliative behavior. Our central therapeutic hypothesis is that VC/VS DBS achieves eventual benefit in OCD by providing the “boost” in pro-approach behavior that allows individuals to overcome their pathological fear-based avoidance. Thus, we focus on the approach-avoidance axis as one of the critical neurobehavioral axes underlying the pathophysiology of OCD. Our overall goal is to develop a mechanistic understanding of DBS for OCD by rigorously investigating the relationship between clinical symptoms, behaviors (i.e., approachful vs. avoidant), and neurophysiology.

#NEWS: Dr. @nicoleprovenza.bsky.social is the recipient of a new $3.7m R01 award from the #NIH & #NIMH for her project, "Neurophysiological investigation of the approach-avoidance axis in OCD: applications to neuromodulation" 🧠

#DBS #OCD #DeepBrainStimulation #ObsessiveCompulsiveDisorder #Research

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