#RNAWorld

Astrobiology

@astrobiology.bsky.social

1 week ago

Sequence Motif Dynamics In RNA Pools - Astrobiology In RNA world scenarios pools of RNA oligomers form strongly interacting

Sequence Motif Dynamics In RNA Pools
astrobiology.com/2026/03/sequ... #astrobiology #originoflife #RNAWorld

Brian D. Wade

@astrobrian.bsky.social

1 month ago

A small polymerase ribozyme that can synthesize itself and its complementary strand The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

A small polymerase ribozyme that can synthesize itself and its complementary strand
#OriginsOfLife #RNAworld

www.science.org/doi/10.1126/...

Origami Organelles

@origamiorganelles.bsky.social

2 months ago

Translation & protein synthesis evolved billions of years ago. Make our paper model & take your students into the #RNAworld for awe-inspiring lessons! Find out more here: buff.ly/ldGJWU2

#iteachbio #proteinsynthesis #RNA #RNAworld #EduSky

Gltch

@gltch.io

2 months ago

Molecular dynamics simulations use atomistic force field to capture RNA folding with high accuracy Ribonucleic acid (RNA) is one of life's most versatile molecules, with roles going far beyond being a messenger of genetic code, as it is fundamentally involved in gene regulation, processing, and maintenance across all living systems. This versatility is deeply tied to RNA's ability to adopt complex three-dimensional shapes, known as secondary and tertiary structures.

RNA: Life’s shapeshifting molecule! 🧬 Beyond codes, it *builds* & *maintains* life itself. Complex forms unlock hidden power. ✨ #RNAworld

Source: phys.org/news/2025-11-molecular-d...

Dr John Freeman

@scifiguy.bsky.social

3 months ago

Scientists and Senators are Excited About the Sugars Found in the OSIRIS-REx Samples It’s been over two years since the samples from Bennu gathered by OSIRIS-REx were returned to Earth. But there’s still plenty of novel science coming out of that 121.6 g of material. Three new papers ...

#asteroid #bennu #origis #RNAworld

Scientists and Senators are Excited About the Sugars Found in the OSIRIS-REx Samples

www.universetoday.com/articles/sci...

Gltch

@gltch.io

3 months ago

RNA in action: Filming ribozyme self-assembly RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study published in Nature Communications by Marcia group, has captured, for the first time, a ribozyme in motion—almost frame by frame. The researchers recorded how this tiny RNA machine folds, flexes, and assembles itself, revealing its intricate choreography in unprecedented detail.

✨Scientists filmed an RNA “machine” folding & flexing—frame by frame!🤯 Witnessing its intricate dance unlocks secrets of life & nano-tech!🔬 #RNAworld

Source: https://phys.org/news/2025-11-rna-action-ribozyme.html

Gltch

@gltch.io

3 months ago

Largest RNA language model to date offers new way to predict behavior and boost drug discovery RNA plays a vital role in how our genes are expressed and how diseases develop. Yet, because RNA molecules constantly change shape, understanding how they work has long been a major scientific challenge.

🧬 RNA: The shapeshifting key to our genes & disease! 🤯 Unlocking its secrets is a huge scientific quest. What wonders will we uncover? ✨ #RNAworld

Source: phys.org/news/2025-11-largest-rna...

GetNews.me

@getnews-me.bsky.social

6 months ago

Scientists Link Amino Acids to RNA in Early Earth Experiment

University College London scientists showed that amino acids can bind to RNA in neutral‑pH water using thioester activation, a step toward early protein synthesis. The work appears in Nature. getnews.me/scientists-link-amino-ac... #originoflife #rnaworld

KumDi

@kumdi.bsky.social

6 months ago

Origin of Life RNA Thioesters Proteins in Water Discover the origin of life RNA thioesters proteins in water and how early chemistry may have sparked protein formation. Explore life’s beginnings today!

🧬 How Life Might Have Begun: The Stunning Role of RNA, Thioesters & Proteins in Water. Unveiling how RNA, thioesters, and proteins may have sparked life in water—revealing chemistry’s ancient secrets. #OriginOfLife #PrebioticChemistry #RNAWorld #KumDi
Read More: kumdi.com/science/orig...

EarthLens

@earthlens.bsky.social

6 months ago

Scientists have shown amino acids can attach to RNA naturally under early Earth conditions using thioesters, providing vital insights into protein synthesis origins and the beginnings of life. 🌍🔬 Link: https://tinyurl.com/22pa2grl #OriginsOfLife #ProteinSynthesis #RNAWorld

FEBS Letters

@febsletters.bsky.social

7 months ago

🌍 Before RNA, could life have started with amyloids? 🧬 Self-replicating β-sheet peptides suggest a co-evolving amyloid–RNA–lipid–protein world – read the newest Perspective: febs.onlinelibrary.wiley.com/doi/10.1002/... #OriginOfLife #AmyloidWorld #RNAWorld

RNA Society Journal

@rnajournal.bsky.social

8 months ago

OLE RNA dimers are depicted as integral membrane noncoding RNAs. This bacterial complex appears to penetrate membranes and mitigate cellular stresses. #ncRNA #RNAWorld @ronbreaker.bsky.social @yalembb.bsky.social bit.ly/3FVn5Cd

Kiya Kersh, EMT, MBA, MSci 🧪

@kiyakersh.bsky.social

8 months ago

I'm skilled in tech strategy, data-materials impact, & systems development.

Though I started in RNA structure + catalysis, molecular evolution, and... neuropsychopharmacology.
This hits home.
This moves me.
#RNAWorld #Nanotech

michael

@proseandpassion.mastodon.social.ap.brid.gy

9 months ago

Chemists recreate how RNA might have reproduced for first time Chemists at UCL (University College London) and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth – a key process in the origin of life.

28-May-2025
Chemists recreate how #RNA might have reproduced for first time

https://www.eurekalert.org/news-releases/1085301 #science #astrobiology #RNAworld #OriginOfLife

Angelika Andrzejewska-Romanowska

@aandrzejewskaa.bsky.social

10 months ago

Rozstrzygnięto konkurs na najlepsze prace doktorskie i magisterskie Już po raz dwudziesty pierwszy Miasto przyznało nagrody za najlepsze prace doktorskie i magisterskie obronione na poznańskich uczelniach i w instytucjach naukowych. W tym roku wyróżnienia odebrało 13 ...

I can proudly announce that the City of #Poznań awarded me for the best #PhD theses! 👏
It shows that the importance of #RNA research in vivo and #RNA genome dynamics of LTR retrotransposons is understood and appreciated by society! #RNAworld ❤️🧬

www.poznan.pl/mim/info/new...

Randall

@createdbyrcw.bsky.social

1 year ago

RNA

Saw this yesterday, & immediately thought of some of the #biopharma clients for whom I do #sciencewriting via Little Dog Communications & my dear friend & champion Jessica Yingling

xkcd.com/3056/

#biology #CentralDogma #RNAworld #xkcd #scicomms

Quijote1

@quijote1.bsky.social

1 year ago

#RNAworld

Olivier Neyrolles

@oneyrolles.bsky.social

1 year ago

Discover this brilliant study by our former student Chuan Wang, revealing how Salmonella thrives in the gut: ManS, a smart sRNA, fine-tunes sialic acid metabolism to boost S. enterica's competitive edge during infection. #Microbiology #MicroSky #RNAworld 🔬

Moreno Colaiacovo 🇪🇺

@emmecola.github.io

1 year ago

Diversity and evolution of viroids and viroid-like agents with circular RNA genomes revealed by metatranscriptome mining Abstract. Viroids, the agents of several plant diseases, are the smallest and simplest known replicators that consist of covalently closed circular (ccc) R

#Viroids are tiny circular RNAs that don't encode for proteins and can replicate in plants. Since their discovery in 1971, only 44 species were known.

This new study found 4,409 viroid-like molecules in diverse environments (not only plants). Are these relics from the #RNAworld?

Deni Szokoli

@szokoli.bsky.social

1 year ago

Protein-free catalysis of DNA hydrolysis and self-integration by a ribozyme Abstract. Group II introns are ancient self-splicing ribozymes and retrotransposons. Though long speculated to have originated before translation, their de

Out now in
@NAR_Open
! A #ribozyme can self-integrate into and hydrolyze ss- & dsDNA, offering a new avenue for the development of protein-free genome editing tools, and hinting at the possibility of a pre-translation origin of group II introns (G2Is). 🧬🧵 (1/7)
#intron #RNAworld

VaidhyaMegha

@vaidhyamegha.bsky.social

1 year ago

VaidhyaMegha on LinkedIn: #originoflife #rnaworld #syntheticbiology #technology 🧬 𝗙𝗿𝗼𝗺 𝗖𝗵𝗮𝗼𝘀 𝘁𝗼 𝗟𝗶𝗳𝗲: 𝗖𝗼𝘂𝗹𝗱 𝗥𝗡𝗔 𝗖𝗼𝗻𝗱𝗲𝗻𝘀𝗮𝘁𝗲𝘀 𝗛𝗼𝗹𝗱 𝘁𝗵𝗲 𝗔𝗻𝘀𝘄𝗲𝗿𝘀? Billions of years ago, life was just an idea…

🧬 𝗙𝗿𝗼𝗺 𝗖𝗵𝗮𝗼𝘀 𝘁𝗼 𝗟𝗶𝗳𝗲: 𝗖𝗼𝘂𝗹𝗱 𝗥𝗡𝗔 𝗖𝗼𝗻𝗱𝗲𝗻𝘀𝗮𝘁𝗲𝘀 𝗛𝗼𝗹𝗱 𝘁𝗵𝗲 𝗔𝗻𝘀𝘄𝗲𝗿𝘀?

Read the full study here: lnkd.in/gP6QbTAS

#OriginOfLife #RNAWorld #SyntheticBiology #technology
#technology #ai #healthcare
www.linkedin.com/feed/update/...

George Giambasu

@ggiambasu.bsky.social

1 year ago

Being aware of #RNA could be useful for medicine, it turns out. Who would have guessed? #RNAWorld #miRNA

Astrobiology

@astrobiology.bsky.social

1 year ago

Protocell Effects on RNA Folding, Function, and Evolution - Astrobiology The early history of life can provide inspiration from the idea of the prebiotic “RNA World” established by ribozymes, in which all genetic and catalytic activities were executed by RNA.

Protocell Effects on RNA Folding, Function, and Evolution
astrobiology.com/2024/09/prot... #astrobiology #RNA #genomics #evolution #RNAWorld

Martin Smith

@martinalexsmith.bsky.social

1 year ago

If you're near Sydney September 5th, stop by @UNSWBABS for A/Prof King's talk on unlocking the immune system's secrets via retrotransposons, long-noncoding #RNA, and #immunology 🧬🔍 #RNAresearch #Biotechnology #RNAWorld #virology #ncRNA #ScienceTwitter

David Shechter

@dshechter.bsky.social

1 year ago

PRMT5's role extends beyond RNA splicing; it dictates mRNA subcellular fate and thereby alters gene expression profiles. Join our discussion and their broader implications for discovery and chemotherapy implications. 3/5 #AcademicChatter #RNAWorld

Astrobiology

@astrobiology.bsky.social

1 year ago

Early Replicators
astrobiology.com/2024/05/earl... #astrobiology #biology #genomics #RNAWorld

Astrobiology

@astrobiology.bsky.social

1 year ago

Development of Allosteric Ribozymes for ATP and l-Histidine Based on the R3C Ligase Ribozyme
astrobiology.com/2024/04/deve... #astrobiology #Genomics #RNAWorld #AbSciCon2024 #AbSciCon

Hao Yin

@haoyin.bsky.social

2 years ago

Patho-DBiT
Spatial #RNAWorld on FFPE section👹
Now tissues can be mapped by RNA variants or non-coding RNAs

Whole transcriptome seq covers
mRNA
LincRNA
microRNA
sn/snoRNA
#AlternativeSplicing
#RNAEditing
RNA #SingleNucleotideVariation

In situ polyA

bioRxiv 2024
www.biorxiv.org/content/10.1...