#XInactivation

Nature Cell Biology

@natcellbio.nature.com

2 months ago

Escape from X inactivation is directly modulated by Xist noncoding RNA - Nature Cell Biology The authors show that increased Xist RNA levels can induce de novo silencing of genes that normally escape X inactivation. SPEN depletion prevents the silencing of escape genes upon Xist RNA overexpre...

☕The authors show that increased #Xist RNA levels can induce de novo silencing of genes that normally escape #Xinactivation. SPEN depletion prevents the silencing of escape genes upon Xist RNA overexpression in neural progenitors. @agneseloda.bsky.social @heardlab.bsky.social
bit.ly/3YUnzhw

Epigenome Technologies

@epigenometech.bsky.social

2 months ago

Epigenetics Update - Escape from X inactivation is directly modulated by Xist noncoding RNA go.nature.com/49jeLH5

Edith Heard and Agnese Loda (EMBL) reporting in Nat Cell Biol

#Epigenetics #Xist #XInactivation #Chromatin
---

Perfect for cancer, immunology, and aging research; epigenometech.com

Climate Change and Maternal Child Health Lab

@gayenlab-iisc.bsky.social

4 months ago

Runumi, from our lab, had a fantastic week at the @embo.org Epitranscriptome workshop at EMBL Heidelberg! She presented her work on the role of m6A RNA modification in #embryogenesis #stemcell specification and #Xinactivation. #EMBOEpitrans
Thanks to IISc, ANRF-India, DBT-India, @insdb.bsky.social

Brian O'Blivion 🅰️👁

@boblivion.bsky.social

11 months ago

#quotes #books #booksky #excerpts #citations #evolutioninfourdimensions #evolution #inheritance #jablonka #lamb #zeligowski #xchromosome #sex #chromosome #female #women #inactivation #epigenetic #xinactivation

Denny Popp

@dennypopp.bsky.social

1 year ago

We solved a puzzling case of Incontinentia Pigmenti by phasing a pathogenic variant in IKBKG to the preferentially inactivated X chromosome and at the same time discriminating gene from pseudogene using #Nanopore long reads.
#HumanGenetics #IncontinentiaPigmenti #XInactivation #LongReads

Colin Purrington

@colinpurrington.bsky.social

1 year ago

Longhaired calico cat beginning to roll upside down on a cardboard scratch pad.

Now that I have some followers it's time to show off my rescue cat, Fluffernutter Purrington. Still kind of feral but loves having her belly rubbed. #cat #caturday #Xinactivation