#cellmigration

Mill_lab

@cilialab.bsky.social

2 months ago

Beautiful talk by @basakissezer.bsky.social @cytolabkoc.bsky.social into fascinating & multifunctional CCDC66 in regulating actin & microtubule crosslinking not just at centrosomes & cilia via #JoubertSyndrome ARMC9/TOGARAM1 complex, but focal adhesions regulating #CellMigration. #UKCilia2026 3/8

Pablo J. Sáez

@pjsaez.bsky.social

2 months ago

#FluorescenceFriday

Proud of our the last paper @cellcommlab.bsky.social & 1st one of @jboixcampos.bsky.social

We continue to study #CellMigration & how cells decide where to go: ↖️↗️⬇️?

(movie of the actin #cytoskeleton)

Full www.science.org/doi/10.1126/...
@focalplane.bsky.social @science.org 🧪🔬

Pablo J. Sáez

@pjsaez.bsky.social

2 months ago

#HappyNewYear !
Let's start 2026 with a @cellcommlab.bsky.social paper

How many branches is OK during #CellMigration?
It depends on the #cell: for ex. immune cells are just fine.

In collab. w. #NirGov @hfspo.bsky.social

Full www.science.org/doi/10.1126/...
@focalplane.bsky.social @science.org 🧪🔬

Yu-Chin (Jean) Lee

@ycjeanlee.bsky.social

2 months ago

Alternate VEGFA isoform expression in fibrosarcoma leads to plasticity in cellular migration and differences in sensitivity to inhibition with anti-VEGFA antibodies Metastasis remains a primary contributor to cancer-related mortality. Elevated expression of soluble vascular endothelial growth factor A (VEGFA) isoforms is linked to increased metastatic potential a...

I am pleased to share that my PhD research has now been published as a preprint on bioRxiv and is available for public review prior to peer review.

#CellMigration #Anti-VEGFA #ECMArchitecture #Metastasis #EngineeredPlatforms

www.biorxiv.org/content/10.1...

Pablo J. Sáez

@pjsaez.bsky.social

3 months ago

Torque-based immune cell chemotaxis in complex environments Directed migration in chemical gradients is crucial to the immune response, yet how immune cells navigate complex tissues remains incompletely understood. Using in vitro migration assays and theoretic...

Hot from the #preprint

Leukocyte + #CellMigration + physics = cool

Microtubules enable torque-based steering during dendritic cell migration.

Actomyosin contractility is required for noise-modulation strategy used by neutrophils.

Full @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

Pablo J. Sáez

@pjsaez.bsky.social

4 months ago

I guess it never gets old...bc we love #CellMigration

ATP has many roles: energy currency, hydrotrope, and *danger signal*

Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!

www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬

Barriga Lab

@eliasbarrigalab.bsky.social

4 months ago

Also grateful to our funders for their support to our research @embo.org @erc.europa.eu @dfg.de 🙏🏼🙏🏼 and to the #xenopus #cellmigration #biomechanics #bioelectricity communities!

MedChemExpress

@medchemexpress.bsky.social

4 months ago

📰New & Featured | #Nature: Researchers found that a cell’s #cytoskeleton behaves like memory foam. This helps cells adjust their shape and navigate complex 3D environments such as #tissues and extracellular matrices.
🧐Read more: www.nature.com/articles/d41...
#CellMigration #Memory

Pablo J. Sáez

@pjsaez.bsky.social

4 months ago

Kudos to @eliasbarrigalab.bsky.social for the Innovation DGZ Prize for his work on #CellMigration

A great Chilean 🇨🇱 in #STEM 💪🏽🔥

@dgz.bsky.social #DGZ50

Journal of Cell Biology

@jcb.org

5 months ago

Patterning in motion: Cell interfaces guide mesenchymal collective migration and #morphogenesis. A new perspective from @maikbischoff.bsky.social & @mayorlab.bsky.social rupress.org/jcb/article/...

#CellBio #CellMigration #Development #Science

Journal of Cell Biology

@jcb.org

5 months ago

Galectin-9 regulates #DendriticCell polarity and uropod contraction by modulating RhoA activity, say Guus Franken, Laia Querol Cano et al. rupress.org/jcb/article/...

#CellMigration #Immunology #Immunotherapy

Rockefeller University Press

@rupress.org

5 months ago

New in @jcb.org: Guus Franken, Laia Querol Cano et al. reveal that galectin-9 is a critical regulator of #DendriticCell basal and chemokine-driven migration by organizing CD44 at the cell surface and promoting RhoA-GEF-H1–mediated signaling. rupress.org/jcb/article/...

#CellMigration #Immunology

Journal of Cell Biology

@jcb.org

5 months ago

Guus Franken, Laia Querol Cano et al. reveal that galectin-9 is a critical regulator of #DendriticCell basal and chemokine-driven migration by organizing CD44 at the cell surface and promoting RhoA-GEF-H1–mediated signaling. rupress.org/jcb/article/...

#CellMigration #Immunology #Immunotherapy

Rockefeller University Press

@rupress.org

5 months ago

New perspective in @jcb.org by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/...

#CellBio #CellMigration #Morphogenesis #Development #Science

Journal of Cell Biology

@jcb.org

5 months ago

New perspective by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/...

#CellBio #CellMigration #Morphogenesis #Development #Science

Zane Alsberga

@zaneals.bsky.social

6 months ago

Curious about how cell “races” can reveal collective behavior? Thrilled to share our findings with you 👇
#cellmigration #immunology #biophysics #cellbiology #PNAS

Peng Huang

@penghuang031.bsky.social

6 months ago

Couldn’t have done this without Emilio’s hard work 🎉 Huge thanks to our amazing co-authors, collaborators, and @CIHR for supporting this fundamental research! #Zebrafish #Fibroblast #CellMigration #Chemoattraction #DevBiol 8/8

@tabdanov.bsky.social

6 months ago

Just posted (bioRxiv): A novel #mechanobiology model revealing how #immune #Tcells combine a #nucleus as a #piston, an #uropod, and #microenvironment to power #amoeboid #cellmigration in #cellconfinement via a hydraulic cell engine. #CellBiophysics #ImmuneMigration
www.biorxiv.org/content/10.1...

ibidi GmbH

@ibidicells.bsky.social

6 months ago

🏆 #Congratulations to Ilenia Masi from CNR, Italy, among the winners of the ibidi Paper Award 2025 in #CellMigration Research for her #publication in @natureportfolio.nature.com Cell Death & Disease📄

🌟Her work uncovers a novel mechanism in ovarian #cancer metastasis🧬

🔗https://zurl.co/q1EWr

#award

FASEB

@faseborg.bsky.social

7 months ago

🧬 Cancer cells migrate as teams, with leaders steering and followers reinforcing invasion. A new review from The FASEB Journal unpacks the plasticity of these roles and their impact on metastasis.
🔗 buff.ly/jF8sMR8

#CancerResearch #CellMigration #FASEBJournal

Dagmar Iber & CoBi

@iberd.bsky.social

7 months ago

Directed cell migration is a versatile mechanism for rapid developmental pattern formation The evolution of multicellular organisms hinges on self-organization mechanisms that generate tissues with diverse functions. A central process is the breaking of symmetry to form spatial patterns fro...

📄 Read the full study here: doi.org/10.1101/2025...

🎯 Useful for: developmental biology, tissue engineering, pattern formation, and computational modeling

#DevBio #PatternFormation #CellMigration #Morphogenesis #ComputationalBiology

Pablo J. Sáez

@pjsaez.bsky.social

7 months ago

More of other scientific research in #microscopy and #bioimaging in their brand new website: complextissue.com
[ doi.org/10.1038/s415... ]

Tks for the invite so the @cellcommlab.bsky.social could contribute with some #CellMigration, congrats to all authors

#BskyScience #cellbio #diabetes #scicomm

ibidi GmbH

@ibidicells.bsky.social

8 months ago

🧶New: Micropatterned Line #Arrays for geometry-guided cell studies!

➡️20 µm adhesive microlanes on a bioinert surface—control shape, adhesion, and cell behavior

🟢Ideal for #neurons, #cellmigration, polarization, alignment & organelle #tracking.

🔍https://ibidi.com/101-line-arrays

Pablo J. Sáez

@pjsaez.bsky.social

8 months ago

This is why we love #cellmigration

#Leukocytes: #Neutrophils (cyan) #Macrophages (orange) chemotaxis.

I couldn't share it before the retirement of @zebrafishrock.bsky.social, but cool #microscopy in #zebrafish continue to rock !

#scicomm #scisky @cellcommlab.bsky.social @focalplane.bsky.social 🧪🔬

Javier Boix

@jboixcampos.bsky.social

8 months ago

🚀 Looking forward to amazing discussions! What computational challenges are you tackling? Let's build the future of biological AI together!

#ComputationalBiology #CellMigration #AI #Introduction

Maik Bischoff

@maikbischoff.bsky.social

8 months ago

What happened to #BioStarterPacks?
People still join here, but we’ve stopped sharing them!
Let’s repost them from time to time to help newcomers find their way 😊

Here’s my starter pack collective: #cellmigration

Comment if you’d like to be added—I haven’t updated it in months 😉

#cellbio #devbio

Daniel Hoffmann 🌼

@danielhoffmann1.bsky.social

8 months ago

Uncertainty-aware quantitative analysis of high-throughput live cell migration data | bioRxiv Motivation Accurate quantification of live cell migration, including velocity, is essential for understanding biological processes such as development, immune function, and cancer metastasis. High-throughput migration assays generate complex, hierarchically structured datasets with technical noise, batch effects, and biological variability, introducing significant uncertainty into velocity estimates. Current statistical approaches often fail to rigorously quantify this uncertainty, undermining reproducibility and comparability across independent experimental datasets. To address this challenge, we present cellmig , a computational tool that employs Bayesian hierarchical modeling to separate biological signals from technical variation while explicitly quantifying uncertainty in migration velocity. Results cellmig provides a robust framework for analyzing cell migration assays, including dose-response studies and large-scale screens with multiple biological and technical replicates. By modeling biological variability (e.g., compound-dependent effects) and technical confounders (e.g., batch variability) within a unified Bayesian framework, cellmig estimates condition-specific effects on cell velocity with probabilistic uncertainty intervals, avoiding common pitfalls associated with null-hypothesis testing. Additionally, its generative models enable simulation of migration velocities under various assumptions, aiding experimental planning. In summary, cellmig enhances reproducibility, reliability, and biological insight in high-throughput migration studies, facilitating inter-dataset comparisons. Availability and Implementation cellmig is an open-source R package, freely available at: <https://github.com/snaketron/cellmig> Contact barbara.gruener{at}uk-essen.de, daniel.hoffmann{at}uni-due.de, simo.kitanovski{at}uni-due.de ### Competing Interest Statement The authors have declared no competing interest.

Substances that slow down migrating cancer cells could be anti-metastatic drug candidates. In this preprint we describe the first computational model for quantitative analysis of cell migration assays for substance screening. #bayes
#cellmigration #metastasis
www.biorxiv.org/content/10.1...

Maik Bischoff

@maikbischoff.bsky.social

8 months ago

For today's #FluorescenceFriday I'm thrilled to share that
ScienceAdvances was so nice to pick my picture as this week's featured image!

It's actually a still of a video😊

Check out the paper to learn more
science.org/doi/10.1126/...

#cellbio #devbio #cellmigration #science

Thank you @aaas.org

Mike Piacentino

@mikepiacentino.bsky.social

9 months ago

We're #hiring! Our group in the Cell Bio Dept at Hopkins is looking for a Research Technologist to join us and study #neuralcrest #cellmigration during #devbiol! Looking to build up your lab experience? Check it out! @socdevbio.bsky.social @ascbiology.bsky.social
jobs.jhu.edu/job/Baltimor...

Maik Bischoff

@maikbischoff.bsky.social

9 months ago

So sad I can't make it this year.
This is such an awesome meeting!

#cellbio #devbio #cellmigration #science