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Posts tagged #ldl

In a phase 1 trial with 6 patients, #lipid nanoparticles for #PCSK9 base editing lowered #LDL without serious adverse events or off-target effects. https://www.nature.com/articles/s41591-026-04254-4

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Praxishandbuch Lernen durch Lehren Lernen durch Lehren (LdL) ist ein in den 1980ern von Jean-Pol Martin entwickeltes Lern-Lehr-Konzept, bei dem Lernende schrittweise die Rolle der Lehrkraft einnehmen. LdL-Anwender*innen berichten von m...

Erinnert mich spontan an #LdL oder @vilsrip.bsky.social ๐Ÿค—? www.beltz.de/fachmedien/p...

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Warum Haferflocken den Cholesterinspiegel schon nach zwei Tagen senken kรถnnen Gerade einmal zwei Tage โ€“ so kurz kann es dauern, bis sich der Cholesterinspiegel messbar verbessert. Entscheidend sind Haferflocken, die fast jeder im Schrank hat.

#Haferbrei anyone? #Was die kurze #Haferkur mit #LDL #Cholesterin #Vorbeugung von #Diabetes und #Mikrobiom zu tun hat ๐Ÿ‘‡โ—โ—โ—

www.t-online.de/gesundheit/a...

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Your Cholesterol Numbers: The Good, the Bad, the Triglycerides A Yale Medicine cardiologist explains how to understand your cholesterol screening numbers.

โ€œBecause Lp(a) is #genetic, people can have high levels even with normal #LDL ..A screening must be ordered separately from the typical #lipid panel and is only required once in a lifetime.โ€: buff.ly/wDzuymF

from @yaleschoolofmed.bsky.social
#HeartHealth #HighCholesterol #cholesterol #MedSky

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Research Progress on the Pathogenesis and Treatment of Neoatherosclerosis

Research Progress on the Pathogenesis and Treatment of Neoatherosclerosis

This review defines #neoatherosclerosis as a distinct in-stent pathology driven by oxidized lipids and #VSMC foam cells, stressing endothelial injury, #inflammation, and need for strategies beyond #LDL reduction to prevent #restenosis. @2024_HUST #stent
Read: doi.org/10.1007/s115...

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DrBalaram Dhotre on Instagram: "โœจ What's YOUR Opinion on Lowering Cholesterol? โœจ I believe that lowering cholesterol is about more than just numbers. It's about repairing the arteries and improving ... 3 likes, 0 comments - coach_drbalaramdhotre on April 9, 2025: "โœจ What's YOUR Opinion on Lowering Cholesterol? โœจ I believe that lowering cholesterol is about more than just numbers. It's about repair...

โœจ What's YOUR Opinion on Lowering Cholesterol? โœจ
I believe that lowering cholesterol is about more than just numbers.
#cholesterol #hearthealth #lifestyle #supplements #vitamins #lpa #ldl #health #wellness #askmeanything
www.instagram.com/p/DIO6hUoz_pj/

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Do ldl Levels Increase or Does Artery Damage Occur? When it comes to heart health, most people think ldl levels increase first and cause artery damage. But is that really how it happens?

๐ŸŽ‰What Happens First: Do LDL Levels Increase or Does Artery Damage Occur?

Read the complete article here:
lyproc.com/what-happens...

#ldl #ldlincrease #highcholesterol #lpa #arterydamage #atherosclerois #heartdiseasereversal #drbalaramdhotre

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Heart health isnโ€™t built in a doctorโ€™s office. Itโ€™s built in your kitchen. What you eat everyday matters more than one visit or one prescription.

Your kitchen is powerful.

#healthsimple #ldl #LDLcholesterol

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Best diet for health, and possibly longevity? ๐Ÿ˜Ž
.
A whole foods plant-based diet ๐Ÿ…๐Ÿซ‘๐Ÿฅ—๐Ÿ„โ€๐ŸŸซ๐Ÿฅ‘๐Ÿ ๐Ÿฅ•๐Ÿ†๐Ÿซ›๐Ÿฅ”๐Ÿฅฌ๐Ÿซœ๐Ÿฅ’๐Ÿ๐Ÿ“๐Ÿซ๐Ÿฅ๐Ÿ‘๐ŸŽ

Why not go vegan today? ๐Ÿ’ช๐Ÿป

#health #diet #ItsTheDiet #cholesterol #LDL #cardiology #nutrition #WFPB #vegan

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High LDL (cholesterol) can be a big issue in lipodystrophy โ€” but there are multiple paths to lowering it.
โ€ข Lifestyle foundations
โ€ข Statins (and why tolerance varies)
โ€ข Non-statin options like ezetimibe, PCSK9 inhibitors, and bempedoic acid
#Lipodystrophy #RareDisease #Cholesterol #LDL

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Efficacy and safety of inclisiran in adolescents with heterozygous familial hypercholesterolaemia (ORION-16): a two-part, randomised, multicentre clinical trial In adolescents with HeFH, inclisiran was effective in lowering LDL cholesterol, with sustained efficacy over 2 years, and was well tolerated. These results support inclisiran as a potentially useful a...

In this adolescent patient population with #HeFH and elevated #LDL #cholesterol despite standard of care, inclisiran was effective in lowering LDL cholesterol, showing sustained efficacy over 2 years of treatment, with a reduction of โˆ’33ยท7% from baseline at day 720 www.thelancet.com/journals/lan....

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New US physician survey identifies barriers and burdens in optimizing LDL-C management, revealing key challenges clinicians face in practice.

๐Ÿ”— https://ow.ly/Lx4R50XSfpf

#LDL #Cholesterol #PreventiveCardiology #HeartHealth #CardioResearch #CardioSky #MedSky

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New research links festive drinking and rich food to higher LDL; these four resolutions help you recover fast.

#cholesterol #JanuaryReset #LDL #newyear
sustainhealth.fit/lifestyle/ld...

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Does siRNA therapy against ANGPTL3 bring new hope in homozygous familial hypercholesterolaemia? Homozygous familial hypercholesterolaemia is a rare and devastating autosomal co-dominant disorder affecting between one in 160โ€‰000 and 300โ€‰000 people in the general population.1 Homozygous familial h...

Linked Comment by Raul D Santos:
Does siRNA therapy against ANGPTL3 bring new hope in #homozygous #familial #hypercholesterolaemia? www.thelancet.com/journals/lan...
#zodasiran #HoFH #LDL #cholesterol

#MedSky #EndoSky #CardioSky

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Zodasiran, an RNAi therapeutic targeting ANGPTL3, for treating patients with homozygous familial hypercholesterolaemia (GATEWAY): an open-label, randomised, phase 2 trial Quarterly dosed zodasiran shows evidence of reductions in LDL cholesterol with a favourable safety profile, in patients with HoFH receiving background lipid-lowering therapy. Further investigation in ...

Quarterly dosed #zodasiran shows evidence of reductions in #LDL #cholesterol with a favourable safety profile, in patients with #HoFH receiving background lipid-lowering therapy www.thelancet.com/journals/lan...
#homozygous #familial #hypercholesterolaemia

#MedSky #EndoSky #CardioSky

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The Buried Truth About High Cholesterol and Heart Disease In today's episode we're challenging the belief that cholesterol is the main cause of heart disease. Did you know 75% of heart attack patients have "normal" cholesterol levels? We dive into 50 years of buried data, including the Minnesota Coronary Experiment, which showed that lowering cholesterol didn't always save livesโ€”it even increased death risk in some cases. We explore why insulin resistance and inflammation are the real culprits, the side effects of statins, and why your body needs cholesterol for brain health. Learn the markers that truly matter. References: https://foodnourish.net/high-cholesterol-and-heart-disease-myth-or-truth/ Become a supporter for just 2โ‚ฌ per month. This removes any advertisements and help us continue bringing more interesting topics and confronting mainstream narrative on health. Link to support: https://www.spreaker.com/podcast/foodnourish-deep-dives--6602003/support

๐Ÿ“ฃ New Podcast! "The Buried Truth About High Cholesterol and Heart Disease" on @Spreaker #arteries #biology #cholesterol #diet #disease #fat #hdl #health #heart #inflammation #insulin #ldl #metabolism #nutrition #plaque #science #statins #sugar #triglycerides #wellness

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LDL ์ฝœ๋ ˆ์Šคํ…Œ๋กค ์ˆ˜์น˜๊ฐ€ ๋†’์œผ๋ฉด ์œ„ํ—˜ํ• ๊นŒ? ์ตœ์‹  ์—ฐ๊ตฌ์™€ ๋‚˜ํ† ํ‚ค๋‚˜์ œ์˜ ํšจ๋Šฅ LDL ์ˆ˜์น˜๊ฐ€ ๋†’์œผ๋ฉด ๋ฌด์กฐ๊ฑด ์œ„ํ—˜ํ• ๊นŒ์š”? 2025๋…„ ์ตœ์‹  ์—ฐ๊ตฌ ๊ฒฐ๊ณผ์™€ LDL ์ƒ์Šน์˜ ์ง„์งœ ์›์ธ, ๊ทธ๋ฆฌ๊ณ  ํ˜ˆ๊ด€ ํ”Œ๋ผํฌ ๊ฐ์†Œ์— ํšจ๊ณผ์ ์ธ ๋‚˜ํ† ํ‚ค๋‚˜์ œ์— ๋Œ€ํ•œ ์ •๋ณด๋ฅผ ํ™•์ธํ•˜์„ธ์š”. ์ˆ˜์น˜ ๋„ˆ๋จธ์˜ ์ง„์งœ ํ˜ˆ๊ด€ ๊ฑด๊ฐ• ๊ด€๋ฆฌ๋ฒ•์„ ์†Œ๊ฐœํ•ฉ๋‹ˆ๋‹ค.

LDL ์ฝœ๋ ˆ์Šคํ…Œ๋กค ์ˆ˜์น˜๊ฐ€ ๋†’์œผ๋ฉด ์œ„ํ—˜ํ• ๊นŒ? ์ตœ์‹  ์—ฐ๊ตฌ์™€ ๋‚˜ํ† ํ‚ค๋‚˜์ œ์˜ ํšจ๋Šฅ #์ฝœ๋ ˆ์Šคํ…Œ๋กค #LDL #๋‚˜ํ† ํ‚ค๋‚˜์ œ

๊ฑด๊ฐ•๊ฒ€์ง„์—์„œ ๋†’์€ LDL ์ฝœ๋ ˆ์Šคํ…Œ๋กค ์ˆ˜์น˜๋ฅผ ๋ณด๊ณ  ๊ฑฑ์ •ํ•˜์…จ๋‚˜์š”? 2025๋…„ ์ตœ์‹  ์—ฐ๊ตฌ๋Š” LDL ์ˆ˜์น˜๋งŒ์œผ๋กœ ์‹ฌ์žฅ์งˆํ™˜ ์œ„ํ—˜์„ ํŒ๋‹จํ•˜๋Š” ๊ฒƒ์— ์˜๋ฌธ์„ ์ œ๊ธฐํ•ฉ๋‹ˆ๋‹ค. ๋‹จ์ˆœํžˆ ์ˆ˜์น˜๋ฅผ ๋‚ฎ์ถ”๋Š” ๊ฒƒ๋ณด๋‹ค ์ค‘์š”ํ•œ '์›์ธ' ํŒŒ์•…๊ณผ ํ˜ˆ๊ด€ ํ”Œ๋ผํฌ ๊ฐ์†Œ์— ๋„์›€์„ ์ฃผ๋Š” ๋‚˜ํ† ํ‚ค๋‚˜์ œ(Nattokinase)์˜ ํšจ๋Šฅ๊นŒ์ง€, ํ˜ˆ๊ด€ ๊ฑด๊ฐ•์˜ ์ง„์‹ค์„ ์ •๋ฆฌํ–ˆ์Šต๋‹ˆ๋‹ค.

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Your Cholesterol Numbers: The Good, the Bad, the Triglycerides A Yale Medicine cardiologist explains how to understand your cholesterol screening numbers.

โ€œ #Lipoprotein (a), or Lp(a), is a sticky, genetically inherited form of bad #cholesterol that contains #LDL. โ€œOver the last decade, weโ€™ve learned that Lp(a) is an independent risk factor for #HeartDisease & #stroke,โ€ Dr. Giaimo says.โ€: buff.ly/7AbHGU7

from @YaleMed.bsky.social

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LDL ์ˆ˜์น˜๊ฐ€ ๋†’์•„๋„ ์‹ฌํ˜ˆ๊ด€ ์งˆํ™˜ ์œ„ํ—˜์ด ๋‚ฎ์„๊นŒ? ๋Œ€์‚ฌ์ ์œผ๋กœ ๊ฑด๊ฐ•ํ•œ ๊ณ ์ฝœ๋ ˆ์Šคํ…Œ๋กคํ˜ˆ์ฆ ์ž„์ƒ ์‚ฌ๋ก€ ๋ฐ ๋ถ„์„ LDL ์ˆ˜์น˜๊ฐ€ ๋†’์•„๋„ ์‹ฌํ˜ˆ๊ด€ ์œ„ํ—˜์ด ์—†์„ ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค. ์šด๋™์„ ์ˆ˜์™€ LCHF ์‹ค์ฒœ์ž์˜ ์ž„์ƒ ์‚ฌ๋ก€๋ฅผ ํ†ตํ•ด ์ˆ˜์น˜๋ณด๋‹ค ์ค‘์š”ํ•œ ์ธ์А๋ฆฐ ์ €ํ•ญ์„ฑ๊ณผ ์—ผ์ฆ ์ง€ํ‘œ๋ฅผ ๋ถ„์„ํ•ฉ๋‹ˆ๋‹ค. ์ˆซ์ž์˜ ๊ณตํฌ์—์„œ ๋ฒ—์–ด๋‚˜ ๋‚ด ๋ชธ์˜ ์ง„์งœ ๋Œ€์‚ฌ ๊ฑด๊ฐ•์„ ํ™•์ธํ•˜๋Š” ํ†ตํ•ฉ์  ์ ‘๊ทผ๋ฒ•์„ ์ง€๊ธˆ ํ™•์ธํ•˜์„ธ์š”.

LDL ์ˆ˜์น˜๊ฐ€ ๋†’์•„๋„ ์‹ฌํ˜ˆ๊ด€ ์งˆํ™˜ ์œ„ํ—˜์ด ๋‚ฎ์„๊นŒ? ๋Œ€์‚ฌ์ ์œผ๋กœ ๊ฑด๊ฐ•ํ•œ ๊ณ ์ฝœ๋ ˆ์Šคํ…Œ๋กคํ˜ˆ์ฆ ์ž„์ƒ ์‚ฌ๋ก€ ๋ฐ ๋ถ„์„ #์ฝœ๋ ˆ์Šคํ…Œ๋กค #LDL

๊ฑด๊ฐ•๊ฒ€์ง„์—์„œ LDL ์ฝœ๋ ˆ์Šคํ…Œ๋กค ์ˆ˜์น˜๊ฐ€ ๋†’๊ฒŒ ๋‚˜์™”์ง€๋งŒ, ๊พธ์ค€ํ•œ ์šด๋™๊ณผ ์ €ํƒ„์ˆ˜ํ™”๋ฌผ ๊ณ ์ง€๋ฐฉ(LCHF) ์‹๋‹จ์„ ์œ ์ง€ํ•˜๋ฉฐ ๊ฑด๊ฐ•ํ•จ์„ ๋А๋ผ๊ณ  ๊ณ„์‹ ๊ฐ€์š”? ๋‹จ์ˆœํžˆ ์ˆ˜์น˜๋งŒ ๋ณด๊ณ  ๋ถˆ์•ˆํ•ดํ•˜๊ฑฐ๋‚˜ ์ฆ‰๊ฐ์ ์ธ ์•ฝ๋ฌผ ์น˜๋ฃŒ๋ฅผ ๊ณ ๋ฏผํ•˜๊ธฐ ์ „์—, ๋Œ€์‚ฌ ๊ฑด๊ฐ•์˜ ์ „์ฒด์ ์ธ ๋งฅ๋ฝ์„ ํŒŒ์•…ํ•˜๋Š” ๊ฒƒ์ด ์ค‘์š”ํ•ฉ๋‹ˆ๋‹ค. ์ตœ๊ทผ ์ž„์ƒ ์‚ฌ๋ก€๋“ค์€ ๋งˆ๋ผํ†ค ์„ ์ˆ˜๋‚˜ ์—„๊ฒฉํ•œ ์‹๋‹จ ๊ด€๋ฆฌ๋ฅผ ํ•˜๋Š” ์‚ฌ๋žŒ๋“ค์—๊ฒŒ์„œ ๋‚˜ํƒ€๋‚˜๋Š” ๋†’์€ LDL ์ˆ˜์น˜๊ฐ€ ๋ณ‘๋ฆฌ์  ํ˜„์ƒ์ด ์•„๋‹Œ, ํšจ์œจ์ ์ธ....

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Did you know that lipodystrophy affects how the body processes fat and cholesteromaking LDL harder to manage?
Diet is one piece of the puzzle, but personalized medical care is essential#RareDiseaseAwareness #Lipodystrophy #LDL #MetabolicCare #Lipodystrophyunited

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Ex: Autopsies of Egyptian mummies, showed narrowing in the arteries of 38% of 54 mummies, including teenagers. A lifetime of avoiding risk factors means cumulative change you can protect yourself before it's too late

#Prevention #PreventativeHealth #LDL #Cardiology #HeartHealth #Inflammation

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Computer-aided design enables repurposing of proprotein convertase subtilisin/kexin type 9 degrader from cholesterol-lowering to colon cancer therapy - Molecular Biomedicine Molecular Biomedicine -

#Letter
omputer-aided design enables #repurposing of proprotein convertase subtilisin/kexin type 9 degrader from #cholesterol-lowering to colon #cancer therapy doi.org/10.1186/s435...

#ColorectalCancer #CRC #PCSK9 #LDL #LDLR #EMT

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ยฟFunciona la pastilla que promete peso ideal y corazรณn sano? Polipรญldora CNIC, LDL bajo y semaglutida 2,4 mg: quรฉ hay tras la superpรญldora que protege corazรณn y reduce peso con evidencia clรญnica sรณlida La respuesta honesta cabe en dos frases. No existe, a dรญa d...

ยฟFunciona la pastilla que promete peso ideal y corazรณn sano? #Cardiologรญa #Salud #Colesterol #LDL #Obesidad #Semaglutida #Polipรญldora #CNIC #PrevenciรณnCardiovascular #Aterosclerosis #GLP1 #4dediciembre #felizjueves donporque.com/pastilla-pes...

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Deferiprone therapy improves the oxidative status of LDL in patients with ฮฒ-thalassaemia/HbE - Drugs in Context This study assesses the protective effect of deferiprone on the oxidative status of low-density lipoproteins in patients with ฮฒ-thalassaemia/haemoglobin E.

๐Ÿ’Š Deferiprone therapy improves the oxidative status of LDL in patients with ฮฒ-thalassaemia/HbE

Tran et al.

#drugsincontext #hematology #ldl #lipidology #pharmacology #MedSky #PharmSky @medsky.social @me.pharmsky.app

www.drugsincontext.com/deferiprone-...

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Here you can see a cryoEM structure of human Apolipoprotein B 100 bound to LDL receptor (PDB code: 9BDT)

Rendering by Francisco J. Enguita made with #ProteinImager

3dproteinimaging.com/protein-imag...

#SciArt #molecularart #apolipoprotein #cholesterol #membrane #receptor #LDL #cryoem

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Colesterolo: la strategia in tre passi per riportarlo nella norma Vuoi riportare il tuo colesterolo nella norma e proteggere il cuore? Ecco i tre passi fondamentali: 1๏ธโƒฃ Riduci i grassi saturi: burro, strutto, olio di palma, latticini grassi, carne e insaccati. 2๏ธโƒฃ Elimina gli zuccheri semplici: zucchero bianco, dolci, bibite zuccherate, carboidrati raffinati. Preferisci dolcificanti vegetali e carboidrati integrali. 3๏ธโƒฃ Mangia cibi โ€œmedicinaโ€: zucca, nocciole, patate dolci e altri alimenti naturali che aiutano a prevenire lโ€™eccesso di grassi nel sangue. https://palcoscenicomondo.blog/2025/11/27/colesterolo-la-strategia-in-tre-passi-per-riportarlo-nella-norma/

๐Ÿ“ฃ New Podcast! "Colesterolo: la strategia in tre passi per riportarlo nella norma" on @Spreaker #alimentazionenaturale #benessere #colesterolo #hdl #ldl #prevenzione #salutedelcuore

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Did you know? When it comes to LDL (โ€œbad cholesterolโ€), there is no one-size-fits-all number for people with lipodystrophy. Always work with a lipodystrophy-experienced clinician to find the LDL range thatโ€™s right for you. ๐Ÿ’™ #Lipodystrophy #LDL #RareDisease #LipodystrophyUnited

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Why click: absolute risk deltas, event curves at low LDL, and when to escalate therapy.

#LDL #cardiology

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A six-year longitudinal study identifies a statin-independent association between low LDL-cholesterol and risk of type 2 diabetes - Cardiovascular Diabetology Background Statin therapy has been associated with increased risk of type 2 diabetes (T2D). We investigated the relationship between Low-Density Lipoprotein Cholesterol (LDL-C) plasma concentrations a...

Hay una asociaciรณn inversa fuerte entre LDL y diabetes tipo 2 en la poblaciรณn general, c/riesgo elevado de diabetes con LDL bajas independientemente de estatinas, por lo que las LDL son un biomarcador potencial de susceptibilidad a diabetes tipo 2 #LDL #T2D cardiab.biomedcentral.com/articles/10....

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Amgenโ€™s new data reinforce weight regain after GLP-1ย discontinuation Amgenโ€™s exec and studyโ€™s author explain that data shows stopping GLP-1s leads to weight regain, while managing LDL-C significantly reduces cardiovascular event risk.

Stopping GLP-1s leads to weight regain, new data from Amgen shows. For high-risk patients, managing LDL-C is key to cutting cardiovascular events.

#News #GLP1 #weightregain #obesity #cardiovascularhealth #LDL #Interviews

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