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#Article in #MedComm
Characterization of #Korean Colorectal Cancer (#CRC) Reveals Novel Driver Gene and Clinically #Relevant #Mutations
doi.org/10.1002/mco2...

#ColorectalCancer #microsatellite #instability #mutational #hotspot #tumor #mutational #sequencing

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For the #lovers of #TCRs -we are looking for #postdocs with interest in #functional and #mutational studies -dare to express 700 #self #antigen #specific #TCRs and #study them in #depth!!!!

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...put the concept of #mutational #scanning on its head. Instead of forward looking mutations, we generated a library of point #revertant #viruses at each position. In this case a point #mutation may restore some recognition of #antibodies and notably increase #serum #neutralization capacity. 4/n

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Photo of Qingli Guo, Benjamin Schuster-Böckler and Ville Mustonen after the public defence. They are smartly dressed in academic gowns and Qingli holds flowers.

Photo of Qingli Guo, Benjamin Schuster-Böckler and Ville Mustonen after the public defence. They are smartly dressed in academic gowns and Qingli holds flowers.

Big congratulations to Dr Qingli Guo for her successful PhD defence yesterday in Helsinki.
Wonderful thesis pushing limits of what we can learn with #mutational signatures.
Thanks to Ben Schuster-Böckler for examining & Ville Mustonen for supervising. Also check out those white bowties!!

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