#BioactiveCompounds

@avhanbidge.bsky.social

1 month ago

#BlueEconomy #MarineBiotechnology #MarineBiodiversity #BlueBiotech #BiotechInnovation #BioDiscovery #AgriTech #Bioinoculants #GreenInnovation #FishFarming #Microbiome #Microbiology #BioactiveCompounds #NaturalProducts #Sustainability #DrugDiscovery #FoodProduction #Bioprotectants #AMR

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JMIR Publications

@jmirpub.bsky.social

2 months ago

Systematic Mining of Bioactive Compounds for Wound Healing From Cayratia Japonica Exosome-Like Nanovesicles: A Workflow Combining LC-MS and DeepSeek Models Background: Plant-derived exosome-like nanovesicles (P-ELNs) effectively deliver bioactive compounds due to their high biocompatibility and low immunogenicity. While LC-MS profiles compounds in complex samples, its analysis of large datasets remains limited by traditional methods. Recent advances in large language models (LLMs) and domain-specific systems now enhance Chinese biomedical data processing and cross-modal pharmaceutical research. Objective: To create a multimodal framework of liquid chromatography-mass spectrometry (LC-MS) combined with DeepSeek models for data mining of compounds with wound-healing properties from exosome-like nanovesicles derived from Cayratia japonica (CJ-ELNs). Methods: LC-MS identified compounds enriched in CJ (N=3) and CJ-ELNs (N=3), then compounds specifically enriched in CJ-ELNs were filtered via a four-step filtering workflow. The CJ-ELNs-specific compounds were processed by DeepSeek models for screening naturally active compounds with targeted functions of antioxidation, anti-inflammation, anti-cellular damage, anti-apoptosis, wound healing and tissue regeneration, and cell proliferation. Results: A multimodal framework of LC-MS combined with the DeepSeek-DF model was created. With the assistance of artificial intelligence (AI), a total of 46 naturally active compounds derived from CJ-ELNs with targeted functions were identified. Conclusions: A self-designed multimodal framework of LC-MS combined with DeepSeek models rapidly and accurately identifies naturally active compounds from CJ-ELNs. This AI-powered system innovatively integrates the traditional analytical technique with modern large language models, thus greatly favoring data mining of active ingredients in traditional Chinese medicine (TCM) herbs.

Systematic Mining of Bioactive Compounds for Wound Healing From Cayratia Japonica Exosome-Like Nanovesicles: A Workflow Combining LC-MS and DeepSeek Models #BioactiveCompounds #WoundHealing #CayratiaJaponica #ExosomeNanovesicles #LCMS

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Proceedings Series MDPI

@proceedingsmdpi.bsky.social

2 months ago

Enzyme-Assisted Extraction of Bioactive Compounds from Origanum dictamnus L.
www.mdpi.com/2673-4591/11...

By Zafeiria Lemoni et al.
From the 4th International Electronic Conference on Processes

#BioactiveCompounds #OriganumDictamnus #NaturalProducts

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@ftbjournal.bsky.social

2 months ago

Quality Characteristics and Storage Stability of Guava Nectar🧃 Formulated with Natural Sweeteners
www.ftb.com.hr/archives/195...
#SDG3 #nonenzymaticbrowining #guava #nectar #naturalsweetener #bioactivecompounds #bioavailableiron

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FeM - Funghi e Micologia

@funghimicologia.bsky.social

4 months ago

Sustainable Cultivation and Functional Bioactive Compounds of Auricularia Mushrooms: Advances, Challenges, and Future Prospects

#Auricularia
#Mushrooms
#Auriculariamushrooms
#bioactivecompounds
#cultivationtechniques
#industrialapplications

www.mdpi.com/2079-7737/14...

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@plantbiocore.bsky.social

7 months ago

We are excited to host colleagues from across Canada and Japan in Kelowna next week to share their latest findings and perspectives on bio/chemical synthesis of natural products.
#NaturalProducts #BioactiveCompounds #Biosynthesis #ChemicalSynthesis #Biotechnology

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Blue Lotus

@bluelotusbuzz.bsky.social

7 months ago

Blue lotus, or Nymphaea caerulea, is related to water lilies but stands apart with unique bioactive compounds like apomorphine and nuciferine. These compounds contribute to its psychoactive and potential therapeutic properties. 🌸✨

#BlueLotus #PlantTaxonomy #NaturalHealing #BioactiveCompounds

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Greenhouse for Mental Health Development

@cito-greenhouse.bsky.social

8 months ago

The Neuroprotective Power of Opuntia ficus-indica YouTube video by Greenhouse for Mental Health Development

The Neuroprotective Power of Opuntia ficus-indica

#PricklyPear #Neurohealth #BrainBoost #NaturalAntioxidants #Neuroprotection #CognitiveHealth #PlantPower #MindAndBody #HealthyBrain #Neuroplasticity #BioactiveCompounds #BrainSupport #Antioxidants #MentalWellness

youtube.com/shorts/JkFkp...

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News Medical

@newsmedical.bsky.social

10 months ago

Pecans and Health: Evidence from Clinical Studies Pecans may support heart health, blood sugar control, brain function, and athletic recovery.

Pecans and Health: Evidence from Clinical Studies 🧠💪🥜 www.news-medical.net/health/Pecan... #Pecans #HeartHealth #BloodSugar #CognitiveHealth #GutHealth #AntiInflammatory #HealthyFats #FunctionalFoods #ClinicalNutrition #BioactiveCompounds

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FeM - Funghi e Micologia

@funghimicologia.bsky.social

11 months ago

Lion’s Mane Mushroom (Hericium erinaceus): A Neuroprotective Fungus with Antioxidant, Anti-Inflammatory, and Antimicrobial Potential - A Narrative Review

#bioactivecompounds
#monkeyhead
#naturalantimicrobials
#polysaccharides
#pom-pommushroom
#terpenoids

www.mdpi.com/2072-6643/17...

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Jose A. Mendiola

@ja-mendiola.bsky.social

11 months ago

✨ Our method significantly increased the yield of bioactive compounds – up to twice as much as pure CO2 extraction! These extracts also showed low cytotoxicity, promising for various applications. 💪 #BioactiveCompounds #FoodIngredients

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Jose A. Mendiola

@ja-mendiola.bsky.social

11 months ago

$Lorena Reyes-Vaquero, Gerardo Álvarez-Rivera, Jose A. Mendiola, Alma Angélica Del Villar-Martínez, Elena Ibáñez, Mónica Bueno, Utilizing green solvents in compressed fluids technologies for extracting bioactive compounds from Ruta graveolens L., Industrial Crops and Products, Volume 216, 2024, 118717, ISSN 0926-6690, https://doi.org/10.1016/j.indcrop.2024.118717. (https://www.sciencedirect.com/science/article/pii/S0926669024006940) Abstract: Ruta graveolens L. is considered an important source of alkaloids and furanocoumarins, with attributed biological activity against phytopathogenic microorganisms. Pressurized liquid extraction (PLE) and supercritical fluid extraction (SFE) using bio-based solvents are green alternative extraction techniques to obtain specific type of compounds. From aerial parts, terpenes were favorably extracted by PLE, while by SFE using batch extraction, different fractions were obtained depending on the extraction pressure: at 200 bar, fatty acids enrichment was achieved from dry sample, while at 350 bar mainly alkaloids and furanocoumarins were obtained from moistened sample. Coumarins were extracted mainly from roots by the two extraction techniques tested. However, this family is always extracted together with alkaloids and furanocoumarins. Therefore, in this work a green methodology has been developed to obtain rue extracts enriched in different families of biologically active substances that could have antifungal or nematicidal activity for pathogen control in agricultural activities. Keywords: Bioactive compounds; Enriched extracts; Hansen solubility parameters; Pressurized liquid extraction; Ruta graveolens L.; Supercritical fluid extraction$

Lorena Reyes-Vaquero, Gerardo Álvarez-Rivera, Jose A. Mendiola, Alma Angélica Del Villar-Martínez, Elena Ibáñez, Mónica Bueno, Utilizing green solvents in compressed fluids technologies for extracting bioactive compounds from Ruta graveolens L., Industrial Crops and Products, Volume 216, 2024, 118717, ISSN 0926-6690, https://doi.org/10.1016/j.indcrop.2024.118717. (https://www.sciencedirect.com/science/article/pii/S0926669024006940) Abstract: Ruta graveolens L. is considered an important source of alkaloids and furanocoumarins, with attributed biological activity against phytopathogenic microorganisms. Pressurized liquid extraction (PLE) and supercritical fluid extraction (SFE) using bio-based solvents are green alternative extraction techniques to obtain specific type of compounds. From aerial parts, terpenes were favorably extracted by PLE, while by SFE using batch extraction, different fractions were obtained depending on the extraction pressure: at 200 bar, fatty acids enrichment was achieved from dry sample, while at 350 bar mainly alkaloids and furanocoumarins were obtained from moistened sample. Coumarins were extracted mainly from roots by the two extraction techniques tested. However, this family is always extracted together with alkaloids and furanocoumarins. Therefore, in this work a green methodology has been developed to obtain rue extracts enriched in different families of biologically active substances that could have antifungal or nematicidal activity for pathogen control in agricultural activities. Keywords: Bioactive compounds; Enriched extracts; Hansen solubility parameters; Pressurized liquid extraction; Ruta graveolens L.; Supercritical fluid extraction

Discover how green solvents and compressed fluids can efficiently extract valuable bioactive compounds from 𝑅𝑢𝑡𝑎 𝑔𝑟𝑎𝑣𝑒𝑜𝑙𝑒𝑛𝑠 L. 🌱
doi.org/10.1016/j.in...
#GreenChemistry #Extraction #BioactiveCompounds #Foodstudies #biomass 🧪🍎📃