Latest posts tagged with #Endosomes on Bluesky
Biogenesis of Rab14-positive Endosome Buds at Golgi-endosome Contacts by the RhoBTB3-SHIP164-Vps26B Complex
#SHIP164, a VPS13-family lipid transporter, forms a Vps26B–SHIP164–RhoBTB3 complex at Golgi–endosome contacts where Rab14 recruits it to #endosomes, driving #LipidTransfer, endosomal budding, cargo sorting, and links to #ParkinsonsDisease.
Read: doi.org/10.1007/s115...
Congrats to Somya Vats et al. from team Galli and collaborators: they show that Vamp7 dependent endosomal secretion acts as quality-control mechanism, that has a particular relevance to cancer.
@inserm.fr @upcite.bsky.social #endosomes #endosomalsecretion
www.nature.com/articles/s41...
Join us today for an exciting @crc1430.bsky.social seminar at @unidue.bsky.social! We’re happy to welcome Christian Ungermann, who will be presenting “Insights into endolysosomal membrane homeostasis.” 🔬✨
#Endosomes #Lysosomes #MembraneTrafficking #CellBiology #MembraneFusion
Very excited for what promises to be a full immersion into #endosomes next year!
Direct measurements of luminal Ca²⁺ with endo-lysosomal GFP-aequorin reveal functional IP3 receptors. New study from Belén Calvo, Sandip Patel, Teresa Alonso @uva-es.bsky.social and colleagues: rupress.org/jcb/article/...
#Technology #Physiology #CellSignaling #Organelles #Lysosomes #Endosomes
Calvo, Patel, Alonso @uva-es.bsky.social et al. describe a new bioluminescent sensor for measuring luminal Ca²⁺ in a mildly acidic subcompartment of the endo-lysosomal system. rupress.org/jcb/article/...
#CellSignaling #Organelles #Physiology #Technology #Lysosomes #Endosomes
In @jcb.org, Calvo, Patel, Alonso @uva-es.bsky.social et al. describe a new bioluminescent sensor for measuring luminal Ca²⁺ in a mildly acidic subcompartment of the endo-lysosomal system. rupress.org/jcb/article/...
#CellSignaling #Organelles #Physiology #Technology #Lysosomes #Endosomes
Analysis of native Ist1 dynamics reveals multiple pools of ESCRT-III on #endosomes. New work from Kevin Swift, Iryna Pustova, Anjon Audhya and colleagues @uwmadison.bsky.social: rupress.org/jcb/article/...
#membrane #lipid
New study from Swift, Pustova, Audhya et al. @uwmadison.bsky.social defines the native dynamics of the ESCRT-III component Ist1 in mammalian cells, highlighting the existence of multiple, unique pools at #endosomes. rupress.org/jcb/article/...
#membrane #lipid
New @jcb.org study from Swift, Pustova, Audhya et al. @uwmadison.bsky.social defines the native dynamics of the ESCRT-III component Ist1 in mammalian cells, highlighting the existence of multiple, unique pools at #endosomes. rupress.org/jcb/article/...
#membrane #lipid
In @jcb.org, Dai et al. @pdc-lab.bsky.social report the localization of BLTP2 in different human cell types & reveal binding partners that mediate its tethering to the PM & to PM-connected structures including certain #endosomes & #macropinosomes undergoing fusion rupress.org/jcb/article/...
@anbangdai.bsky.social et al. @pdc-lab.bsky.social report the localization of BLTP2 in different human cell types & reveal binding partners that mediate its tethering to the PM & to PM-connected structures including certain #endosomes & #macropinosomes undergoing fusion rupress.org/jcb/article/...
"It's official 🎉: Our remote magnetic control of #endosomes, driving invasive protrusions in living cells, has landed in #ScienceAdvances! #Magnetogenetics meets #Rabs! The journey was wild, but it works! 🔥 www.science.org/doi/full/10....
@imgprague.bsky.social #3Dmatrix #CellBiology
@science.org
Szentgyörgyi, Lueck, @spanglab.bsky.social, Bakhtiar et al. show that Arf1-dependent LRBA recruitment to Rab4 #endosomes is required for endolysosome homeostasis. rupress.org/jcb/article/...
📕 In Immune Cell Biology 2025: rupress.org/jcb/collecti...
#AAI2025
CCSer2 gates #dynein activity at the cell periphery, say Juliana Zang, Morgan DeSantis and colleagues @umich.edu: rupress.org/jcb/article/...
#Migration #motility #Biochemistry #Biophysics #Cytoskeleton #Centrosomes #endosomes #zebrafish
We got the cover!!! Check out our new story in EMBO J. #endosomes #c.elegans #membranes #GTPases
Vacuoles provide the source membrane for TORC1-containing signaling #endosomes, say Kenji Muneshige and Riko Hatakeyama @hatakeyama-lab.bsky.social @uniofaberdeen.bsky.social: rupress.org/jcb/article/...
#Genetics #CellSignaling #Organelles
Muneshige & @hatakeyama-lab.bsky.social @uniofaberdeen.bsky.social find that vacuoles supply membrane during the formation of TORC1-containing signaling #endosomes in yeast in a process mediated by the membrane-cutting CROP complex and promoted by TORC1 kinase activity. rupress.org/jcb/article/...
Gao, Ungermann et al. identify Any1 as a #lipid scramblase that cycles btwn #Golgi and #endosomes and promotes MVB biogenesis. To do so, Any1 cooperates with the lipid transfer protein Vps13, possibly at a contact site with the ER and #LipidDroplets rupress.org/jcb/article/...
Such a great pleasure to host @dplamartin.bsky.social at UoB! A day full of cool science about #mitochondria, #endosomes and #mtDNA! Thank you for the visit!
María Lucas @IBBTEC and co-workers found that selective #cargo and #membrane recognition by SNX17 regulates its interaction with #Retriever, essential for recycling specific cargos from #endosomes to the #plasma membrane
-> www.embopress.org/doi/full/10....
𝗞𝗲𝘆 𝗙𝗶𝗻𝗱𝗶𝗻𝗴𝘀
This study reveals that enterovirus-containing #endosomes can deform and rupture, enabling the release of genome-containing particles into the cytoplasm.
3/9
Beautiful imaging on the cover but also check out the beautiful imaging inside and our story on #endosomes and #GTPase cascades
👋🏻Our November issue's out!
Cover: Imaging #Ovulation
👉🏼Comments on #embryo models & #MembraneContactSites
🔬on: #PlasmaMembrane #endosomes #CellDeath #metabolism #mTOR #BiomolecularCondensation #gastruloids #organoids #ProteinQualityControl & more!
www.nature.com/ncb/volumes/...
A live imaging approach spatiotemporally dissects mouse ovulation ex vivo. by Thomas, Marx et al.
☕Our November issue's out folks!
👉🏼Comments on #embryo models & #MembraneContactSites
🔬on: #ovulation #imaging #endosomes #CellDeath #metabolism #mTOR #BiomolecularCondensation #gastruloids #organoids #ProteinQualityControl & more!
www.nature.com/ncb/volumes/...
@natureportfolio.bsky.social
as in @LauraENewman1 et al. show that, upon #mtDNA #ReplicationStress, enlarged nucleoids are trafficked to #endosomes. Endosomal rupture releases mtDNA in the cytoplasm, activating #cGASSTING.
@manorlaboratory, @salkinstitute
👉🏾
rdcu.be/dyV6K
