Check out our latest episode!
Dr. Rafi Ahmed from Emory University talks about his research on #ImmuneMemory.
Listen now: https://bit.ly/4bjqWpO
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#ImmuneMemory
Latest posts tagged with #ImmuneMemory on Bluesky
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Posts tagged #ImmuneMemory
🧬🍽️ Your macrophages may be carrying your mother’s metabolic history!
In our @cp-trendsimmuno.bsky.social article, we discuss how maternal diet programs lifelong immune function.
authors.elsevier.com/sd/article/S...
#ImmuneMemory #Macrophages #MaternalNutrition #DOHaD #EarlyLifeProgramming
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Innate immune memory is wild 🧠
Alexander Lercher from Rockefeller dives into how cells remember past infections and prep for future ones. Type I interferon doing way more than just fighting viruses!
Full interview: buff.ly/5TKEJ9o
#CytokineSociety #ImmuneMemory #TypeIInterferon #CellsHaveMemoriesToo
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#drugdevelopment #Oncology #FosunPharma #TEV56278 #Teva #monotherapy #combinationtherapy #pembrolizumab #clinicaldatageneration #antiPD1IL2ATTENUKINEtherapy #antitumourTcellactivity #MerckandCo #MSD #enhancedTcellinfiltration #immunememory #preclinicalstudies
pharmatimes.com/news/teva-an...
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Models capturing different kinetics and relationships between the cell populations of interest. Model A: Independent homogeneous model. Each population (TN, CD95int, CD95hi) is independent and homogeneous. Model B: Independent heterogeneous model. Each population (TN, CD95int, CD95hi) is independent and allowed (but not constrained) to be heterogeneous. Model C: Forked differentiation model. Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k); a fraction (f) differentiate into the CD95int pool with the remainder differentiating into the CD95hi pool. Model D: Linear differentiation model (CD95int first). Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k) and differentiate into the CD95int pool which subsequently differentiate into the CD95hi pool. Model E: Linear differentiation model (CD95hi first). Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k) and differentiate into the CD95hi pool which subsequently differentiate into the CD95int pool. Note for compactness, in the cartoons, CD95int TSCM are designated Tint and CD95hi TSCM are designated Thi. In every model each population was assumed to be of constant size. The models were fitted to the data to identify which model was most consistent with the experimental observations and to quantify the population parameters.
How do T stem cell-like memory (TSCM) cells act to maintain long-term #ImmuneMemory? This study reveals that human #TSCM cells comprise two distinct subpopulations with complementary roles; 1. Supporting clonal longevity. 2. Driving expansion & self-renewal @plosbiology.org 🧪 plos.io/4kQi0tL
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Models capturing different kinetics and relationships between the cell populations of interest. Model A: Independent homogeneous model. Each population (TN, CD95int, CD95hi) is independent and homogeneous. Model B: Independent heterogeneous model. Each population (TN, CD95int, CD95hi) is independent and allowed (but not constrained) to be heterogeneous. Model C: Forked differentiation model. Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k); a fraction (f) differentiate into the CD95int pool with the remainder differentiating into the CD95hi pool. Model D: Linear differentiation model (CD95int first). Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k) and differentiate into the CD95int pool which subsequently differentiate into the CD95hi pool. Model E: Linear differentiation model (CD95hi first). Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k) and differentiate into the CD95hi pool which subsequently differentiate into the CD95int pool. Note for compactness, in the cartoons, CD95int TSCM are designated Tint and CD95hi TSCM are designated Thi. In every model each population was assumed to be of constant size. The models were fitted to the data to identify which model was most consistent with the experimental observations and to quantify the population parameters.
How do T stem cell-like memory (TSCM) cells act to maintain long-term #ImmuneMemory? This study reveals that human #TSCM cells comprise two distinct subpopulations with complementary roles; 1. Supporting clonal longevity. 2. Driving expansion & self-renewal @plosbiology.org 🧪 plos.io/4kQi0tL
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Models capturing different kinetics and relationships between the cell populations of interest. Model A: Independent homogeneous model. Each population (TN, CD95int, CD95hi) is independent and homogeneous. Model B: Independent heterogeneous model. Each population (TN, CD95int, CD95hi) is independent and allowed (but not constrained) to be heterogeneous. Model C: Forked differentiation model. Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k); a fraction (f) differentiate into the CD95int pool with the remainder differentiating into the CD95hi pool. Model D: Linear differentiation model (CD95int first). Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k) and differentiate into the CD95int pool which subsequently differentiate into the CD95hi pool. Model E: Linear differentiation model (CD95hi first). Upon meeting cognate antigen, TN cells undergo a clonal burst (of size 2k) and differentiate into the CD95hi pool which subsequently differentiate into the CD95int pool. Note for compactness, in the cartoons, CD95int TSCM are designated Tint and CD95hi TSCM are designated Thi. In every model each population was assumed to be of constant size. The models were fitted to the data to identify which model was most consistent with the experimental observations and to quantify the population parameters.
How do T stem cell-like memory (TSCM) cells act to maintain long-term #ImmuneMemory? This study reveals that human #TSCM cells comprise two distinct subpopulations with complementary roles; 1. Supporting clonal longevity. 2. Driving expansion & self-renewal @plosbiology.org 🧪 plos.io/4kQi0tL
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NK cells share a universal signature of memory with B and T cells. Come to my presentation at AAI to find out more.
Sunday April 4th 9:30am Room 316C
#AAI2025 #NKcells #ImmuneMemory
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#Medsky🧪#IDsky #Immunosky #publichealth #Immunememory is essential for the effectiveness #Covid19vaccination
🔥 #COVID19 💉induces durable #Bcell responses in exposed & naive humans
🔥Spike+ #Bcells gradually expand toward the recognition of the RBD subdomain
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Discover how mRNA vaccines do more than fight COVID-19—they reprogram your immune system for lasting defense. #mRNAVaccine #ImmuneMemory #HealthInnovation
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Same Arm Boosts CoVid Vax Responses: CoVid vaccinations in the same arm boosts your initial protective antibody responses 4.5 fold. #vaccinate #samearm #immunememory #CoVid #shingles #pneumonia
www.instagram.com/drhowardsmit...
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Get vaccinated!
"So 10 to 20 percent of people infected with #Measles have the #ImmuneMemory of other infections or vaccinations wiped out, Elledge says. That may leave them vulnerable to illnesses in the future even if they were previously infected or vaccinated against bacteria and viruses."
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#Measles infection *can* kill, but it also does this insidious thing where it makes your immune system forget how to fight other infections — for as long as three years. That’s always a bad thing, but worse in our #pandemic times.
#ImmuneMemory
news.harvard.edu/gazette/stor...
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#Measles infection *can* kill, but it also does this insidious thing where it makes your immune system forget how to fight other infections — for as long as three years. That’s always a bad thing, but worse in our #pandemic times.
#ImmuneMemory
news.harvard.edu/gazette/stor...
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Study of 2022 compares immune responses across four #COVID-19 #vaccines (Moderna, Pfizer, Janssen, Novavax). mRNA vaccines show stronger antibody levels and cellular immunity, while all promote memory B cells. Highlights mRNA's edge for durability amid evolving variants. #ImmuneMemory
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Long COVID patients maintain robust immune memory two years after infection 🔬💪🦠 www.news-medical.net/news/2024091... #LongCOVID #Immunology #SARSCoV2 #Tcells #Bcells #COVID19 #ImmuneMemory #Vaccination #Research #Health
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Upper airway swabs reveal rich, stable immune memory crucial for respiratory defense 🔬🧬🦠 www.news-medical.net/news/2024080... #Immunology #UpperAirway #COVID19 #ImmuneMemory #MucosalImmunity #Research #Virology #InfectionDefense #BCells #TCells @natureportfolio.bsky.social
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