Latest posts tagged with #IonChannel on Bluesky
#CallForPapers ⏰️ Don't miss the March 15th deadline! Submit your research on topics including #IonChannel structure and biophysical properties, regulatory mechanisms, pharmacology, physiological functions, disease relevance, and drug discovery 👉 rupress.org/JGP/pages/ca...
Ramon Latore treats the audience to an inspirational retrospective on the operation of BK Channels as the Keynote Speaker at the #BPS2026 Satellite Meeting on Drug Discovery.
A fitting kickoff to a week of #science 🧪 #biophysics #ionchannel in SF!
After a safe, even if long, travel to SF yesterday, I am so looking forward to peeking into new discoveries, forging a positive future, reconnecting with brilliant minds, and making new friends.
If you are at #BPS2026, come say hello, and make my day 🥰!!
#science 🧪 #biophysics #ionchannel #bps2026
Happy birthday to #LaskerLaureate Roderick MacKinnon! He was recognized for the elucidation of the structure & function of potassium channels, providing the first molecular description of a selective #ionchannel. 🧪
The Rockefeller University
📖 https://ow.ly/EC6Y50YhWnc
🎧 https://ow.ly/Pcw150YhWn8
📣 #CallForPapers 📣 Emerging Research on Ion Channels in Health and Disease. Submit your research on topics including #IonChannel structure and biophysical properties, regulatory mechanisms, pharmacology, physiological functions, disease relevance, and drug discovery. 👉 rupress.org/JGP/pages/ca...
📣 #CallForPapers 📣 Emerging Research on Ion Channels in Health and Disease. Submit your research on topics including #IonChannel structure and biophysical properties, regulatory mechanisms, pharmacology, physiological functions, disease relevance, and drug discovery. 👉 rupress.org/JGP/pages/ca...
Easily detect & quantify changes in #ionchannel activity using #FlowCytometry
ION Biosciences Flow Cytometric Potassium Channel Assay is the first assay solution for #SingleCell, high throughput measurements of #potassiumchannel activity
👉https://tinyurl.com/83j3fc7m
#neuroscience #microbiology
Large-scale investigation confirms TRPM3 ion channel dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Sonya Marshall-Gradisnik et al. 🇦🇺
#ME/CFS #TRPM3 #IonChannel
Don't miss this great coming meeting on channelopathies. Early bird registration until Dec 15th. #channelopathies #channelopathy #ionchannel #neuroscience #disease #physiology #pharmacology #electrophysiology #patchclamp
New from our lab: More evidence that ion channels play a key role in high-grade glioma and represent promising therapeutic targets.
🔗 link.springer.com/article/10.1...
🔗 academic.oup.com/neuro-oncolo...
#highgradeglioma #ionchannel #braincancer
Not that new, but worth a post - a nice calcium binding site in the pore of the trimeric Bile Acid Sensing #ionchannel BASIC.
www.nature.com/articles/s41...
New review highlights emerging insights into KCNE–Kv channel interactions, their organ-specific roles, and how these discoveries may drive next-generation therapies for #IonChannel disorders. #medsky
#OpenAccess: www.sciencedirect.com/science/arti...
Thank you @amglazer.bsky.social for the exciting opportunity to collaborate! Since then, we've provided functional evidence supporting the VUS reclassification in children with abnormal sodium #ionchannel function at Sydney Children’s Hospital.
Interesting #IonChannel story about an enzyme removing burn-inducing compounds from spirits.
www.wired.com/story/booze-...
🚨🆕🧪🔬That “wild-type” Nav1.5 variant everyone’s been using may not be so WT after all. Melgari et al. reveal T559A causes loss-of-function ⚡️❌ decades of WT controls weren’t truly WT, time to double-check those studies🧐🧬
#IonChannel #Physiology #Reproducibility
journals.physiology.org/doi/full/10....
Mechanism of conductance control and neurosteroid binding in NMDA #IonChannel receptors | Nature
Sorry it is paywalled…. But look at the beautiful channels 🥲
www.nature.com/articles/s41...
Substrate stiffness attenuates cardiomyocyte depolarization slope via sodium channel modulation (Increased stiffness of the substrate causes the dysfunction of Nav1.5 #Ionchannel kinetics) www.sciencedirect.com/science/arti...
Aberrant HCN4 #ionchannel expression: Impacts on neuronal excitability and implications for epilepsy pathogenesis - Spyrou - British Journal of Pharmacology
Paywalled
bpspubs.onlinelibrary.wiley.com/doi/10.1111/...
Massive reduction of RyR1 #Ionchannel in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosis - Ruiz - The Journal of Physiology
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Augmenting AMPA #IonChannel signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery - Nature Neuroscience
www.nature.com/articles/s41...
A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 #IonChannel receptor - Nature Communications
www.nature.com/articles/s41...
Distinctive GABA A #Ionchannel receptor subunit expression modulates cell specific EMT and functional responses in glioblastoma breast and ovarian cancer - Scientific Reports
www.nature.com/articles/s41...
Calmodulin binding is required for calcium mediated TRPA1 #IonChannel desensitization | Nature Communications
www.nature.com/articles/s41...
A conserved mechanism of LRRC8 #ionchannel inhibition by two structurally distinct drugs | Communications Biology www.nature.com/articles/s42...
Open access
New in @jgp.org: Zangerl-Plessl, Lee, et al. utilized MD simulations to reveal that PIP2 potentiated clockwise twisting motions in individual Kir2 #IonChannel cytoplasmic subunits, as well as concerted dynamics among the four subunits. rupress.org/jgp/article/...
@colinnicholslab.bsky.social
Eva-Maria Zangerl-Plessl, Sun-Joo Lee, et al. utilized MD simulations to reveal that PIP2 potentiated clockwise twisting motions in individual Kir2 #IonChannel cytoplasmic subunits, as well as concerted dynamics among the four subunits. rupress.org/jgp/article/...
@colinnicholslab.bsky.social
Ion Channel DmMSL10 Identified as Venus Flytrap Touch Sensor
Researchers identified the ion channel DmMSL10 as the molecular sensor that lets Venus flytrap hairs detect faint touches, triggering calcium spikes and electrical signals that close the trap. getnews.me/ion-channel-dmmsl10-iden... #venusflytrap #ionchannel
Great to see this paper with @elainetao.bsky.social out in print at the Biophysical Journal. Using Alphafold to study conformational transitions in 32 voltage-gated channel superfamily members #ionchannel #AI #StructuralBiology
www.sciencedirect.com/science/arti...
Ion channels control the flow of ions across membranes, governing everything from nerve impulses to cardiac rhythms. With small molecule activators and inhibitors, researchers can modulate channel activity with precision. 🧪
#ChemSky #BioSky #MedChem #IonChannel
fluorochem.co.uk/product-cate...
