The March 2026 issue of @jmdiagn.bsky.social is now live!
Full issue: https://www.jmdjournal.org/issue/S1525-1578(25)X0004-0
#NextGenSeq #Oncogene #CompanionDiagnostics
0
0
0
0
#Oncogene
Latest posts tagged with #Oncogene on Bluesky
Trending
Posts tagged #Oncogene
🆕 ADVANCE ONLINE 🆕
CANCER METABOLISM REVIEW: Metabolic permissiveness: how tissue context shapes cancer
By Chrysanthi Moschandrea and Christian Frezza
➡️ genesdev.cshlp.org/content/early/2026/02/09...
#cancermetabolism #oncogene #tumorsuppressor #mutation #TCAcycle
0
0
0
0
New Spotlight in @aacrjournals.bsky.social
#Oncogene × #Ontogeny × #Plasticity shape leukemia biology & therapy response.
Two complementary studies show: mutations alone don’t explain disease behavior—developmental state and cellular plasticity matter.
aacrjournals.org/bloodcancerd...
🩸🧬
EpiSci
7
4
1
0
LATS1 Promotes B-ALL Tumorigenesis by Regulating YAP1 Phosphorylation and Subcellular Localization
This study identified YAP1 as an #Oncogene in NALM6 cells and showed that LATS1 downregulates YAP1-Ser127 phosphorylation, highlighting YAP1 as a novel diagnostic & #TherapeuticTarget in B-cell acute lymphoblastic leukemia patients.
Read: doi.org/10.1007/s115...
1
1
0
0
This review explores #MYCN-driven #oncogenesis in #neuroblastoma, outlines emerging therapies, and highlights that dual targeting of MYCN and the #MDM2 #oncogene is a promising strategy for high-risk neuroblastoma and other #cancers. @uh.edu
#OpenAccess: doi.org/10.1016/j.ge...
2
2
0
0
How do anti-oncogenes work?
An oncogene mutation is not sufficient to cause an oncological disorder, because the body has protective mechanisms (anti-oncogenes).
Anti-oncogenes counteract oncogenes and create balance.
#cancer #oncogene #oncology #health
0
0
0
0
#RecercaUB | Publicat a la revista #Oncogene, del grup @nature.com, el nou treball científic és de caràcter preclínic.
#fàrmac #palbociclib #càncercolorectal
0
0
0
0
In a review article published in the Journal #Oncogene, Bernard Lopez proposes that #RAD51 -mediated homologous recombination is a Pro-tumour driver pathway, contradicting the generally accepted dogma
institutcochin.fr/en/news/plot...
@cnrsbiologie.bsky.social @inserm.fr @upcite.bsky.social
2
0
0
1
The extent to which dynamic changes in #oncogene activity shape cancer cell #metabolism and drive disease progression remains poorly understood.
2/n
0
0
1
0
Bayer and Kumquat Biosciences enter global exclusive #license and #collaboration to develop and commercialize Kumquat's #KRAS G12D inhibitor. Phase 1a study will initiate H2 2025
Total deal up to $1.3 billion
#oncology #pharma #oncogene #therapeutics
www.prnewswire.com/news-release...
1
0
0
0
Rac1 and Toll signalling induce activated JNK and Mmp1. (A) Expression of the JNK transcriptional target Mmp1 upon transgene induction via RT-qPCR. (B,C) Representative immunoblotting and quantification of p-JNK protein after silencing of Toll immune signalling in the presence of RasV12 at 14 days induction. (D) Western blotting against p-JNK after 7 days of RasV12 induction, shows increased JNK phosphorylation in RasV12 expressing flies. Syx, Syntaxin as a loading control. n=3 biological replicates, 100 hindguts per replicate; error bars: s.d., one-way ANOVA: *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.
Myrofora Panagi & co from @ucy1.bsky.social use the fruit fly hindgut epithelium to uncover adjunct nodes of pro-metastatic RasV12 signalling—opening doors to new therapeutic targets. 🪰
doi.org/10.1242/bio....
#Drosophila #Oncogene
0
0
0
0
Perspective: Zhu et al. discuss the rise of RAS: how gradual oncogene activation shapes the OIS spectrum @narita-lab.bsky.social
➡️ tinyurl.com/gd352761
#oncogene #cancer #senescence #SASP #physiology #tumorigenesis #tumor #RAS #NOTCH #dose #cellstate #inflammation #replicativestress #openaccess
1
0
0
0
🔎 Spotted in #Oncogene by @natureportfolio.nature.com!
Researchers from @uhn.ca's Toronto General Hospital Research Institute, among others, used 6 of DSHB's anti-MHC isoforms in a study on the role of pRB and p130 in maintaining adult skeletal muscle integrity and function.
1
1
1
0
New Paper Alert: Breakthrough iNKT Cell Therapy Achieves Complete Remission in Metastatic Germ Cell Tumor
oncodaily.com/oncolibrary/...
#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #iNKT #iNKTCellTherapy #GermCellTumor #Oncogene
7
1
0
0
New #Oncogene journal paper: The tumor suppressor pRb and its relative p130 are required to maintain murine adult skeletal muscle homeostasis. #Myoblue tinyurl.com/4j64jvy6
6
1
0
0
Excited to share that I’m now part of the Editorial Board of Oncogene. I’ve long been a fan of the journal and look forward to contributing to its continued excellence #Oncogene #NaturePublishingGroup
www.nature.com/onc/
0
0
0
0
IEO Announces Public “Di Martedì” Event on Clinical Research in Oncogene-Addicted NSCLC - Antonio Passaro
@antoniopassaro.bsky.social
oncodaily.com/blog/di-mart...
#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #IEO #NSCLC #Oncogene
6
1
0
0
Oncogenic MORC2 in cancer development and beyond
This review provides an overview of MORC2 as an #oncogene, detailing its role in various aspects of #tumorigenesis and #DrugResistance. It also summarizes the different upstream regulators and downstream target genes of MORC2. #NuclearProteins #medsky
#OpenAccess: buff.ly/7bkvSyQ
0
0
0
0
Pleased to share and amplify our most recent paper. Looking at #oncogene effects in the #drosophila #prostate which is #postmitotic and #polyploid. 🧪
5
1
0
0
We also investigate the phenotypic heterogeneity of MCF10A human mammary gland #organoids expressing various #oncogenes, which is an #organoid model of #BreastCancer. #oncogene
0
0
1
0
Mouse model of #MetaplasticBreastCancer
Mammary epithelial Ccn6 KO🐭->
1⃣⏬Mammary gland #BranchingMorphogenesis
2⃣⏫ incidence of mammary carcinoma b/w 10~21 mo
Mimicking human Spindle MpBC (CD10+p63+Vim+ Tri-neg), invasive margin
sharing 14% DEGs
#Oncogene 2017
www.nature.com/articles/onc...
2
0
0
0
AI review of my book:
"Cancer Virus Hunters is a well-researched comprehensive history that focuses on the scientists who led the discoveries, their work, and how the study of tumor viruses led to breakthroughs in molecular biology and the first cancer vaccines."
#Cancer #HPV #HBV #HCV #oncogene
0
0
0
0
New iBioSeminar by Nobel Laureate J. Michael Bishop titled Cancer: The rise of the genetic paradigm #cancer #oncogene
www.ibioseminars.org/lectures/cell-bio-a-med/...
0
0
0
0