Latest posts tagged with #Polygenic on Bluesky
#PolygenicScores: What They Mean for #Aging and #Disability - Learn how #polygenic risk scores work, what they predict, and why they matter for #seniors facing age-related #diseases and #disabilities - www.disabled-world.com/disability/p...
📣 New Podcast! "Polygenic Risk, Polygenic Scores, Polygenic Indices: What Are They? What Should Be Done with Them?" on @Spreaker #bioethics #embryo #embryos #genetic #genetics #genomic #genomics #polygenic
New research highlights the importance of better patient-provider communication about #breast #cancer risk and bridging gaps in #polygenic #risk score literacy to boost personalized screening uptake. bit.ly/4iHwkVe #PRS
We are starting the second scientific session at #LIIGHColloquium2025 on population genetics and palaeogenomics with @delvecchyo.bsky.social's talk on how the accuracy of #polygenic scores in ancient samples is affected by natural selection @liigh-unam.bsky.social
Combining polygenic risk scores with rare variant data has potential to refine diagnostic accuracy and improve genetic counseling.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #DEE #genetics #penetrance #polygenic #PRS
#Polygenic Risk Scores Predicting Estimated #GFR Validated With #Iohexol Clearance
#VIsualAbstract by Brian Rifkin
www.kireports.org/article/S2468-0249(25)00...
"In contrast to #diseases such as..#CysticFibrosis, where #mutations in a single gene cause a disease, chronic diseases tend to be #polygenic, meaning they're influenced by multiple mutations at many #genes across the whole genome": buff.ly/18Z8mF1
via @LiveScience.com
Children with higher #polygenic scores showed accelerated #BMI gain from age 2.5 years to adolescence and greater adult weight gain.
Read More: https://bit.ly/4mWrWT5
Disease predicting #polygenic risk scores #PRS do not predict the severity of disease.
Susceptibility #PRS will therefore not stratify the most economically-demanding populations for focussed intervention.
So, simple #PRS application will not be a shortcut to effectively-focussed healthcare.
"In contrast to #diseases such as..#CysticFibrosis, where #mutations in a single gene cause a disease, chronic diseases tend to be #polygenic, meaning they're influenced by multiple mutations at many #genes across the whole genome.": buff.ly/fBwNv9t
via @livescience.com
Happy to share our new work on #polygenic scores and child and adolescent #MentalHealth symptons 🧬🧠
vhir.vallhebron.com/en/society/n...
SCI member @lindakachuri.bsky.social and colleagues show that adding #polygenic risk scores to multimodal classifiers improves molecular subtyping before surgery. The approach enhanced prediction of isocitrate dehydrogenase mutation status in #glioma patients. www.nature.com/articles/s41...
Excited to share my commentary on integrating #transancestry #polygenic risk scores and family history for predicting #psychiatric disorders in #Taiwan #Biobank - now online in Biological Psychiatry
👉 authors.elsevier.com/a/1lduY1S07x...
Do you analyse #polygenic scores across ancestry groups? See Oliver Pain's extension to the GenoPred pipeline, with recommendations for good practice and efficient analysis. @oliverpain.bsky.social
🔗 Paper: lnkd.in/evJ9daBF
🔗 GenoPred pipeline: lnkd.in/eKwFr9kQ
www.linkedin.com/posts/oliver...
"Like many other #AutoimmuneDiseases, #AntiphospholipidSyndrome is #polygenic, where multiple #genes are involved..The individual contribution of each #gene may even be unnoticeable, and requires multiple contributing factors to activate.": buff.ly/cRzATCt
#ChronicIllness
📣New from @bpasaniuc.bsky.social & co
📄Exploring #depression treatment response by using #polygenic risk scoring across diverse populations
Our explainable #AI preprint that uses a Kolmogorov-Arnold model (#KAN) to predict childhood #obesity using early-life factors and #polygenic risk.
IDH mutations are some of the most informative prognostic markers for #glioma. Our small, proof-of-concept study shows that #multimodal classifiers that include #polygenic risk scores can improve pre-operative molecular subtyping: www.nature.com/articles/s41... 🧠🧬
@stanford-cancer.bsky.social
Curious about how #polygenic risk scores are used in research and healthcare?
Join Dr Jodi Thomas and Dr Brittany Mitchell (#QIMR Berghofer) for a free workshop on Thursday, July 24. 11:00–12:30 at AHMS.
Must register here: docs.google.com/forms/d/e/1F...
#Genetics #PRS #QIMR #AdelaideEvents
#Polygenic prediction of #cellular #immune responses to #mumps #vaccines
#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...
Extremely proud of @mmdewit.bsky.social for leading this comprehensive study on the #autism #polygenic score. Check out the interactive tool to easily find the association with your phenotype of interest!
Clinical #implementation of #polygenic risk scores requires clear evidence of benefits and actionability guidelines. Clear evidence of benefits and actionable guidelines should be required. bit.ly/4jL7zXB #PRS #healthcaredelivery
Genetic pathways explain why some people grow tall and others stay short 🧬📏🔍 www.news-medical.net/news/2025040... #Genetics #Height #Growth #GWAS #Polygenic #Monogenic #Epigenetics #Endocrinology #BoneHealth #HumanBiology
🚨 Training opportunity 🚨
📌 Polygenic Risk Score Analysis Workshop
📅 22nd - 27th June 2025
📍 Kampala, Uganda 🇺🇬
⌛️Application deadline 1st April 2025
🔗 coursesandconferences.wellcomeconnectingscience.org/event/polyge...
#Genetics #Polygenic #Risk #Score #Africa #PGS
#Polygenic risk scores have made progress towards viable clinical applications over 2024, particularly w/resp to #cardiovascular disease, while evidence for the clinical utility of embryo PRS testing remains insufficient. My latest for GenomeWeb drupal.prod.genomeweb.com/genetic-rese...
From the 5/2024 AMS issue (IF=3.0): Risk of adverse #cardiovascular #events based on common genetic variants in 8-year follow-up of the #LIPIDOGEN2015 population using the #polygenic #risk #score (PRS): #study #design and methodology.
www.archivesofmedicalscience.com/Risk-of-adve...
This festive season 🎄 give the gift 🎁 of a #bayesian model to a friend still trying to run a frequentist linkage mapping approach looking for significant associations 🧬🖥️
#genomics #QuantitativeGenetics #polygenic #omnigenic
Dr. Eugene Braunwald gave an amazing #GrandRounds on the directions of #cardiology in the next #decade! Topics covered:
#polygenic #risk #scores🧬
#primordial #prevention 👶
#dyslipidemias 🍔
#ArtificialIntelligence 🤖
#AntiInflammatoryDrugs 💊
#CHIP 🩸
youtube.com/watch?v=ybMT-9…
