Our proposal for managing combination therapy while awaiting for susceptibility in Pseudomonas infections.
Find out more: journals.plos.org/plosone/arti... #AMSsky #IDsky #PsWatch
Latest posts tagged with #PsWatch on Bluesky
Our proposal for managing combination therapy while awaiting for susceptibility in Pseudomonas infections.
Find out more: journals.plos.org/plosone/arti... #AMSsky #IDsky #PsWatch
Combined antipseudomonal therapy does not improve outcomes and may increase toxicity.
Its main role is ensuring appropriate empirical therapy in severe infections, with no proven benefit once susceptibility is known.
📖 A systematic review: www.tandfonline.com/doi/full/10.... #AMSsky #IDsky #PsWatch
This is a classic review on Pseudomonas:
journals.asm.org/doi/epub/10....
And here you’ll find some more recent data on resistance against new betalactams:
www.sciencedirect.com/science/arti...
Hope you find it useful! #PsWatch #IDsky
Can we use Ciprofloxacin for treating Levofloxacin-R Pseudomonas and viceversa? 🤔
#AMSsky #PsWatch 👇🏻👇🏻
Different approaches to preparing and sequencing bacterial RNA libraries capture comparable transcriptional profiles:
journals.asm.org/doi/10.1128/...
#microsky #PsWatch #bacteria
The Pseudomonas Genome Database is now on Bluesky with the Pseudomonas.com web address! We encourage using the #pseudomonas hashtag to note interesting research #pseudomonas #bacteria #microsky #idsky #PsWatch
Despite our growing antibiotic arsenal, non-fermenting GNB frequently keep leaving us without therapeutic options.
This article explores the present and the future of therapies against DTR NF-GNB: journals.lww.com/co-infectiou...
#PsWatch #AMSsky #IDsky
Great initiative!
Would you please sign us up?
Also, we’ve created a dedicated feed on P. aeruginosa, in case you find it useful: bsky.app/profile/did:...
Tag your posts with #PsWatch to join the conversation!
How long should we treat uncomplicated P. aeruginosa BSIs? Here’s a thread on the evidence we’ve got 👇🏻
#AMSsky #IDSky #PsWatch
With our @shorten2trial.bsky.social RCT we will hopefully provide further specific data on P. aeruginosa BSIs, including those occurring in immunocompromised hosts 🤞🏻
#ShorterIsBetter #PsWatch #AMSsky #IDSky #IDOnc #TxID
The recent BALANCE RCT (N=3600) proved 7-day course as the new standard for uncomplicated BSI!
www.nejm.org/doi/full/10....
However, <5% of BSIs were by P. aeruginosa (n=170), probably due to the exclusion of immunocompromised hosts, with no etiology-specific data provided.
#PsWatch #AMSsky #IDSky
MDR-P. aeruginosa is usually underrepresented in studies on treatment duration, including the former meta-analysis.
In this later study on HAP/VAP by MDR-PsA, no improved outcomes were observed with treatments >8d either:
📚 bmcinfectdis.biomedcentral.com/articles/10....
#PsWatch #AMSsky #IDSky
What's the best duration for treating uncomplicated P. aeruginosa-BSI?
This metaanalysis of observational studies (n=1746)
found no differences in recurrence+mortality for short (<10d) compared to prolonged treatments.
📖 www.journalofhospitalinfection.com/article/S019...
#PsWatch #AMSsky #IDsky
New β-lactams allow treating Pseudomonas that were untreatable, but… are they better than previous options?
This meta-analysis of RCTs shows they are not superior to prior alternatives when available: www.ajicjournal.org/article/S019...
👐🏻 Use them wisely, make them last
#PsWatch #AMSsky #IDsky