#Secretome

Institut de Myologie

@institutdemyologie.bsky.social

3 months ago

#JSFM2025 Présentation des travaux de Barbara Crisol du @crm-myologie.bsky.social de @institutdemyologie.bsky.social : " Effects of aging in the muscle secretome, a multi-omic approach" aux Journées de la Société Française de Myologie.
@capucinetrollet.bsky.social
#muscle #secretome #vieillissement

Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

5 months ago

#TGFβ1 drives maladaptive #BoneMarrow (BM) endothelial cells (ECs), impairing #vascular regeneration and #hematopoietic support via a #secretome shift, while #TGFβ1 inhibition or #Luspatercept restores BM EC function. @pku1898.bsky.social #medsky

#STTT: doi.org/10.1038/s413...

Thiard News@F4F

@newsen.bsky.social

5 months ago

RoosterBio and Secretome Therapeutics Celebrate Milestone in Large-Scale Cell Therapy Production RoosterBio and Secretome Therapeutics have completed a significant milestone in the production process for a promising heart therapy candidate, STM-01. This achievement enhances scalability and patient access.

RoosterBio and Secretome Therapeutics Celebrate Milestone in Large-Scale Cell Therapy Production #USA #STM-01 #RoosterBio #Secretome #Frederick,_MD

Bérénice A. Benayoun, PhD

@bbparis1984.bsky.social

7 months ago

Thus, we decided to overexpress #AluJB in primary IMR90 fibroblasts, and perform multi-omic profiling of its impact on the #transcriptome, #proteome and #secretome. We were surprised to see large scale multi-omic remodeling in response to #AluJB. 4/9

Dr Laurent Chatre

@laurentchatre.bsky.social

10 months ago

Calciprotein particle-activated endothelial cells aggravate smooth muscle cell calcification via paracrine signalling - Cellular and Molecular Life Sciences Background Vascular calcification is highly prevalent in Chronic Kidney Disease (CKD) and is associated with markedly increased cardiovascular risk. High serum phosphate in CKD increases calcification...

Our latest collaborative effort to improve our knowledge
🔬 One name:
#Calciprotein particle
🧪 One pathway:
#Calcification and #secretome
🥇 The place:
From the #Endothelium to vascular #muscle

It's in Cellular and Molecular Life Sciences @springernature.com
link.springer.com/article/10.1...

Genes & Diseases Journal

@genesndiseases.bsky.social

11 months ago

MicroRNAs in adipose tissue fibrosis: Mechanisms and therapeutic potential

This review discusses the role and mechanisms of various #miRNAs in promoting #AdiposeTissueFibrosis & explores the mechanisms and advantages of miRNA-transfected adipose-derived stem cells #secretome in mitigating adipose tissue fibrosis. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Reproductive BioMedicine Online

@rbmonline.bsky.social

1 year ago

This new review summarises the molecular markers analyzed in spent embryo culture medium and their potential for assessing embryo quality and predicting success in IVF outcomes.

The paper is free to read from our in-press articles now:

doi.org/10.1016/j.rb...

#ClinicalEmbryology #Secretome

Genes & Diseases Journal

@genesndiseases.bsky.social

1 year ago

Effects of microenvironment and biological behavior on the paracrine function of stem cells Mesenchymal stem cells (MSCs), the most well-studied cell type in the field of stem cell therapy, have multi-lineage differentiation and self-renewal …

Latest review in Genes & Diseases! This review discusses how the microenvironment and biological behavior influence the #secretome of #MesenchymalStemCells, which in turn affects its paracrine functions. #RegenerativeMedicine #medsky

#OpenAccess: www.sciencedirect.co...