#alloHSCT

Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

3 months ago

This study identifies PD-1+CD8+ TSCM-like regulatory cells in G-CSF–mobilized donors that balance #GVHD suppression and #GraftVersusLeukemia preservation after #alloHSCT, revealing a potential #biomarker for optimal donor selection.

#OpenAccess #STTT: doi.org/10.1038/s413...

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Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

6 months ago

A donor PD-1+CD8+ TSCM-like regulatory subset mobilized by G-CSF alleviates recipient acute graft-versus-host-disease - Signal Transduction and Targeted Therapy Signal Transduction and Targeted Therapy - A donor PD-1+CD8+ TSCM-like regulatory subset mobilized by G-CSF alleviates recipient acute graft-versus-host-disease

Scientists identified a donor-derived PD-1⁺CD8⁺ TSCM-like regulatory subset that alleviates #aGvHD, preserves GVL, supports immune reconstitution, offering #biomarkers for donor selection & potential cell therapy in #alloHSCT.

#STTT #OpenAccess: doi.org/10.1038/s413...

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@henrymorello25.bsky.social

8 months ago

#Modulen-IBD for the prevention of #malnutrition and maybe #GVHD in #alloHSCT and promising effects on #microbiota
Ready to start recruitment for the multicenter #RCT (NCT07010068).
authors.elsevier.com/a/1lNYT8Yy15...
@sghmd.bsky.social

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MaaT Pharma

@maatpharma.bsky.social

10 months ago

📄 [EHA2025] – MaaT Pharma To Present Updated Data for MaaT013 in Early Access Program at the European Hematology Association (EHA) Annual Congress.

👉 Read the press release: www.maatpharma.com/may-14-2025-...

#EHA #EAP #Phase3 #aGvHD #alloHSCT #Microbiome #Oncology #Cancer #Hematology