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This review shows how #methylation modulates #microRNA biogenesis, stability, and function, influencing proliferation, #apoptosis, #tumorigenesis, and #HostPathogenInteractions as a flexible layer of gene regulation.

#OpenAccess: doi.org/10.1016/j.ge...

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Inflammasome Activation Differences Underpin Different Mycobacterium tuberculosis Infection Outcomes Summary: PAMPS of Mtb interacts with PRRs of host cells and activates intracellular signaling, leading to activation of the inflammasome complex, which differentially contributes to the progressive o...

#Article in #MedComm
Inflammasome Activation Differences Underpin Different Mycobacterium tuberculosis Infection Outcomes doi.org/10.1002/mco2..., studied by Dr. Selvakumar Subbian and his group from @RutgersUniversity

#HostPathogenInteractions #ImmuneResponse #infection #tuberculosis

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Electron microscopy image of tubular membrane structures (in orange) of an infected endothelial cell, produced by meningococcus.
Credit: Mathieu Coureuil.

Electron microscopy image of tubular membrane structures (in orange) of an infected endothelial cell, produced by meningococcus. Credit: Mathieu Coureuil.

Work by A. Laurent & K. Sollier, in collaboration between the teams of Stefano Marullo (U1016), Mathieu Coureuil (U1151), and Nicolas Borghi (UMR7592), published in Nat. Commun.! 🔎Doi: doi.org/10.1038/s414...
#Research #LifeSciences #BiomedicalResearch #InfectiousDiseases #HostPathogenInteractions

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Finally, we show a heat-stable RNase-sensitive salivary factor boosts infection; if identified could provide a potential target for new antivirals or vaccines
#VectorBiology #Arboviruses #Immunology #Virology #SandFlies #SkinBiology #HostPathogenInteractions

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#MalariaResearch
#StructuralBiology
#VaccineDevelopment
#Biophysics
#InfectiousDiseases
#ParasiteBiology
#ProteinStructure
#HostPathogenInteractions
#StructuralVaccinology
#GlobalHealth @oxfordbiochemistry.bsky.social @parasitematt.bsky.social @medsci.ox.ac.uk #KavliOxford

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Pleased to have co-chaired the 2025 Rutgers Symposium with @jackhsu.bsky.social #hostpathogeninteractions #immunometabolism
Many thanks to all our speakers! @aiinglim.bsky.social @shanluliu.bsky.social @roi1avraham.bsky.social @briandaniels.bsky.social and many others

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Her #newlab explores virus-virus host interactions, #immune #metabolism & symbiosis. Whether it's studying lipid droplets or viral replication dynamics, she believes in following what fascinates. P.S - she is #hiring and seeking motivated students.
#arbovirus #mosquito #hostpathogeninteractions.

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Oropouche Virus: More Questions than Answers Oropouche virus (genus Orthobunyavirus, family Peribunyaviridae) is an arthropod-borne virus that infects several species of animals and humans, primarily in South America.

#OropoucheVirus: More Questions than Answers.

Read More: tinyurl.com/2thf9rx4

#OROV #Orthobunyavirus #OneHealth #vectors #hostpathogeninteractions #vertebratehosts #Zoonoses #Zoonosis #Zoonotics @scienceopen.bsky.social

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Studying the genetic basis of ecological interactions with intergenomic epistasis

https://doi.org/10.1111/oik.10835

#GxGInteractions #SpeciesInteractions #CoEvolution #HostPathogenInteractions #Epistasis #EcoEvolutionaryDynamics

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2/ Within 15 minutes of infection, T. gondii causes host cells to arrest in the S-phase of the cell cycle. This rapid effect, seen in endothelial cells, relies on the parasite’s MYR1 protein but not HCE1.
#CellCycle #HostPathogenInteractions

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Oropouche Virus: More Questions than Answers Oropouche virus (genus Orthobunyavirus, family Peribunyaviridae) is an arthropod-borne virus that infects several species of animals and humans, primarily in South America.

Oropouche Virus: More Questions than Answers

Read More: bit.ly/4gxoMSU

#animalhealth #hostpathogeninteractions #OneHealth #OropoucheVirus #Zoonoses #Zoonosis #Zoonotics #Zoonoticdiseases @scienceopen.bsky.social

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