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Latest posts tagged with #smallmolecule on Bluesky

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Posts tagged #smallmolecule

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RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA-binding proteins (RBPs) as key post-transcriptional regulators of ...

#Review in #MedComm_Oncology
#RNA-Binding Proteins (#RBP) and #Ferroptosis in #Cancer: Mechanism and Therapeutic Implications doi.org/10.1002/mog2...

#ClinicalPotential #SmallMolecule

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Germany's #BoehringerIngelheim could sink up to $500 million into a #partnership with UK start-up #Sitryx focused on a family of #smallmolecule drugs for #autoimmune and #inflammatory diseases.

buff.ly/QiBzfGU

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Redirecting

🧬 Just published online in JPS❣️ (📖 Open Access!! 03 February 2026)
“Identification of a Small Molecule that Targets Activator of G-protein Signaling 8”
— Alamgir Hossain et al.
🔗 doi.org/10.1016/j.jp...
#GPCRsignaling #SmallMolecule #SignalTransduction #NowOnline #JPhysiolSci

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Gut bacteria molecule boosts lung cancer immunotherapy – BioNews Central Researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy in mice and can now be made into a drug for testing in humans. ...

Researchers have discovered a #SmallMolecule produced naturally by #GutBacteria that doubled the response to #LungCancer #immunotherapy in mice and can now be made into a #drug for testing in humans.
#LungCancerTreatment #CombinationTherapy #MicrobialMetabolite

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Now Iktos teams up with Pierre Fabre in oncology As Servier announces its partnership with Paris, France-based Iktos, now Pierre Fabre Laboratories has revealed an integrated collaboration with Iktos

In the same week that #Servier announced its partnership with Paris, France-based #Iktos, now #PierreFabreLaboratories has revealed an integrated collaboration with Iktos to identify and develop novel #smallmolecule drug candidates in #oncology.

pharmaphorum.com/news/now-ikt...

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Variational AI at JPM Week and Biotech Showcase 2026 - Variational AI

Variational AI at JPM Week and Biotech Showcase 2026 - Variational AI

@VariationalAI will be in San Francisco for #JPMWeek this January. We’ll be meeting biotech & pharma teams to discuss how #GenerativeAI can accelerate their early #SmallMolecule discovery programs.
Let’s connect 👉 https://hubs.ly/Q03XlpBd0
#DrugDiscovery #GenAIinPharma

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The second project aims to tackle #AntimicrobialResistance by developing new strategies to strengthen the immune system. 🧪

Instead of attacking the bacteria directly, they use #SmallMolecule FPR1 agonists that boost the #ImmuneSystem.

Learn more: www.scilifelab.se/news/scilife...

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SISYPHOS: An automatic procedure for the serial refinement of single-crystal diffraction data in Olex2 A program for serial handling of crystallographic data is presented within Olex2. Especially for small molecule electron and x-ray diffraction, the handling of

A nice #Olex2 feature on serial refinement in #SmallMolecule #diffraction 😀😀 doi.org/10.1063/4.00...
#ResonantDiffraction #crystallography #education

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#EroomsLaw got drug discovery down? Not for long!

New whitepaper, "The #DigitalTransformation Roadmap," reveals how #AI, #automation & data analytics are reversing rising costs & slowing timelines in #smallmolecule #drugdiscovery

Reverse Eroom's Law & unlock productivity: lnkd.in/gQ8NhbAD

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#TechnologyTuesday
𝗧𝗵𝗶𝗼𝘂𝗿𝗲𝗮 𝗔𝗻𝘁𝗶𝗯𝗶𝗼𝘁𝗶𝗰𝘀 𝗳𝗼𝗿 𝗔𝗰𝗶𝗻𝗲𝘁𝗼𝗯𝗮𝗰𝘁𝗲𝗿 𝗯𝗮𝘂𝗺𝗮𝗻𝗻𝗶𝗶

🔬 @helmholtzhzi.bsky.social

🔎 Learn more about this #technology on our website: www.ascenion.de/technologiea...

#Antibiotics #AMR #Acinetobacter #GramNegative #InfectiousDiseases #SmallMolecule #ESKAPE

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Topping off #EFMCISCB25 we had an exciting talk on #molecularglue #TPD from @monterosatx.bsky.social
Nice to see how rapidly the rational discovery and of #smallmolecule degraders is developing and the insight these platforms are providing into #biology @euromedchem.bsky.social

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Agonism of the glutamate receptor GluK2 suppresses dermal mast cell activation and cutaneous inflammation Small-molecule agonism of GluK2 reduces dermal mast cell responses to MrgprB2 ligation and suppresses skin inflammation.

www.science.org/doi/10.1126/...

Activation of glutamate receptor GluK2 with a topical
#smallmolecule inhibits dermal #mastcell degranulation in #eczema
Possible applications for this mechanism in #allergy ?
#immunosky
#medsky
🧪

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As the year draws to a close, we want to extend our heartfelt appreciation to our dedicated team, valued partners, and the
patients we serve. We are incredibly proud of the progress we’ve made this year in advancing the field of
#SmallMolecule therapies. #YearInReview #TrueToOurRNA

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🚀 Explore the latest insights into the #SmallMoleculeInnovator CDMO Market! Uncover key trends, market dynamics, and growth opportunities.
Read more: www.knowledge-sourcing.com/report/small...
#Pharmaceuticals #Biotech #CDMO #SmallMolecule #MarketTrends #HealthcareInnovation #MedicalAdvancements

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