Potential broad #coronavirus #drug target ...
| #infections | #RNA | #tRNA | #antiviral | #drugs | Via @sciencex.bsky.social
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#tRNA
Latest posts tagged with #tRNA on Bluesky
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Posts tagged #tRNA
Please check out our latest #preprint to study #ACTIVELY TRANSLATING #tRNA populations and their dynamics upon #stress :) This was an wonderful collaborative effort between @novoalab.bsky.social @immagina.bsky.social and #Soares teams - thank you for making this possible!
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🧬 RNA types work together in protein synthesis 🔬—mRNA carries code, tRNA delivers amino acids, and rRNA builds proteins efficiently 📘.
#TypesOfRNA #mRNA #tRNA #rRNA #ProteinSynthesis #MolecularBiology #LifeScienceStudents #Biotechnology #BiologyConcepts #BioResire
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⛸️🧬 February RNA Modifications Newsletter
From CRISPR-triggered tRNA tail cleavage to temperature-responsive rRNA modifications, ribosome QC, and pathway-specific rRNA modification during biogenesis.
#RNAmods #Epitranscriptomics #Ribosome #Translation #tRNA #rRNA
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🧬 Understanding RNA types is essential 🔬—mRNA, tRNA, and rRNA work together to drive accurate protein synthesis in cells 📘.
#TypesOfRNA #mRNA #tRNA #rRNA #MolecularBiology #ProteinSynthesis #LifeScienceStudents #Biotechnology #Microbiology #BioResire
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Robert W. Holley, #LaskerLaureate, was born #OTD. He was the first to determine the chemical structure of a nucleic acid; it was that of an alanine #tRNA. 🧪
Cornell University
http://ow.ly/iI2P30mTqXS
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Interested in direct tRNA-seq by Nanopore? We developed a new RNA-based barcoding aproach for seq parallelization; it is also cost-saving. Scripts available on github. #tRNA #Nanopore
track.smtpsendmail.com/9032119/c?p=...
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Here you can see the crystal structure of the complex of M. tuberculosis PheRS with cognate precursor tRNA (PDB code: 9DSX)
Rendering by Francisco J. Enguita made with #ProteinImager
3dproteinimaging.com/protein-imag...
#SciArt #molecularart #tuberculosis #tRNA #PheRS #xray
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PhD position in RNA Biology at Humboldt-Universität zu Berlin, group Ehrenhofer-Murray! Starting date May 1, 2026 or thereafter. Application deadline Feb. 15, 2026 #nanopore #tRNA @humboldtuni.bsky.social
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If you’re at #JPMWeek, check out Wednesday’s live recording of The Genetics Podcast for a conversation on translating emerging RNA and gene-editing modalities into meaningful patient benefit, featuring Alltrna CEO @mcw44.bsky.social.
bit.ly/3YxH8w5
#tRNA #StopCodonDisease #RNAsky #JPM26
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As a rare disease mom, I know how much it matters when progress starts to feel real. In 2025, Alltrna took big leaps to advance our first #tRNA medicine towards the clinic. I’m deeply proud of this team and energized by what lies ahead!
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Our new paper finally in #NAR as Breakthrough paper! Wobble uridine #tRNA modifications have more diverse functions during #translation than previously thought. #tRNA modification defects do not affect all #codons in the same way.
Great work by Jie and Cristian. With help from many.
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⭐NAR Breakthrough! ⭐
🔬 #tRNA modifications fine-tune #translation; in yeast, their loss slows #ribosomes at hard-to-read codon pairs, causing collisions ⚠️, and cells deploy quality control pathways to prevent #proteotoxicstress and ensure survival.
🧬Read more: doi.org/10.1093/nar/...
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🎄Our last issue for 2025 is out!
Cover: human trunk development model
🔬 #EmbryoModels #proteostasis #tRNA #ferroptosis #trogocytosis #mechanobiology #chromatin #TranscriptionFactor #epigenetics #ExtracellularVesicles #hematopoiesis #cancer #PhaseSeparation & more!
www.nature.com/ncb/volumes/...
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Using a phage-inspired genetic screen and biochem, NEB, Harvard Medical School, and University of Illinois Urbana-Champaign researchers discovered OLD inactivates tRNAs by a completely novel mechanism: severing anticodon arms! https://nebiolabs.com/4rysTEk
#tRNA #PhageDefense
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Thrilled to share our new preprint on the evolution of transfer RNA (tRNA) genes in photosynthetic organisms, together with David Pflieger, Alexandre Berr, and Laurence Drouard!
#PlantGenomics #Evolution #tRNA
@ibmp-cnrs.bsky.social
arxiv.org/abs/2511.01943
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Recent #Research by Allison Spillane of uwhealth.bsky.social et al. investigates precision therapeutic #tRNA rescue of nonsense mutation R166X in KCNJ13 to restore K+ channel function 🧬 🔬
📜 Read it here: www.jprecisionmedicine.org/article/S305...
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At the 2nd MENA Congress for Metabolism in Health and Disease 2025, Alltrna highlighted how engineered #tRNA medicines can restore protein synthesis in liver #StopCodonDisease and inborn errors of metabolism.
metabolism.ae
#RNAsky
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On the way back from one week of great science, technology and therapeutic potentials of RNA in organization of Immagina Biotechnology S.r.l. and Massimiliano Clamer. Thanks for the great meeting to Max and the Immagina team. Looking forward to future collaborations.
#RNA #tRNA #ribosome
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It wouldn’t be an #ImmaginaRNA25 symposium without a talk held by one of our employees!
Our R&D project manager, Alessia, will present “tRNA fragments as new biomarkers for early & non-invasive skin cancer detection.”
Just 1 week to go! 🤩
Learn more 👉 zurl.co/MvIhV
#RNA #ribosome #tRNA
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95% of genetic #rarediseases lack therapies. On #InternationalPodcastDay, Alltrna CEO @mcw44.bsky.social shares how engineered #tRNA medicines can restore protein production and uniquely treat many diseases with the same underlying mutation.
bit.ly/3VR6LXd
#RNAsky #StopCodonDisease
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New method enables simultaneous synthesis of all 21 tRNAs in vitro
A new tRNA array method creates all 21 tRNA species from one plasmid in a cell‑free system, reported in a 2025 Nature Communications paper. getnews.me/new-method-enables-simul... #syntheticbiology #trna
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Congrats to our colleagues at Flagship Pioneering on 25 years of turning bold ideas into medicines. At Alltrna, we’re building on this legacy of #BiggerLeaps by pioneering #tRNA medicines to unify treatment across #StopCodonDisease and redefine what’s possible for patients.
#FlagshipFounded
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New #RNA tool to advance #cancer and #infectious #disease research and treatment ...
| #antibioticresistance | #infection | #AMR | #tRNA | Via @mit.edu
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🔬 Recap – Protein Synthesis & Translational Control 2025 @embl.org
We showcased our technologies Ribo-tRNAseq & HT-RiboSeq (RiboWich), connected with brilliant scientists & had inspiring conversations 🤩 Thanks to all who joined us in Heidelberg!
#ribosome #tRNA #EMBLProtein #riboseq
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