🌅 #Research #Alert
MTA1-mediated #transcriptional repression of #Cox2 confers #resistance against #neutrophil infiltration in #endometritis
@springernature.com #Genes & #immunity
www.nature.com/articles/s41...
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#Neutrophil
Latest posts tagged with #Neutrophil on Bluesky
Trending
Posts tagged #Neutrophil
Would a patient's #breastCancer develop #resistance to #therapy? X. Zhang, L Yu et al found a way to predict it. @jci.org @bcmhouston.bsky.social #macrophages #neutrophil blogs.bcm.edu/2026/03/03/f...
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Available here linda-howes.pixels.com/featured/hum...
#wallartforsale #wallart #gifts #giftideas #Health #Neutrophil #MRSA #Micrography #infection #immuneCel #phagocytosis #bacteria #neutrophils #methicillinResistantStaphylococcusAureus #NatioinalInstituteOfHealthImages
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Daniel Kim, Ramizah Syahirah, Qing Deng and colleagues @cancer-inst-purdue.bsky.social report that #RABEP1 is necessary for #Neutrophil migration - "RABEP1 regulates neutrophil migration via endosomal recycling and actin polymerization"
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Available here linda-howes.pixels.com/featured/whi...
#Wallartforsale #wallart #gifts #giftideas #NIAID #Whitebloodcell #MRSA #bacteria #ElectronMicroscope #infection #microbiology #neutrophil #science #Health
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Like normal #hillock cells described by Jay Rajagopal's lab, #hillock-like tumor cells are slow-cycling, stress-resistant (especially to platinum and oxidative stress) and exhibit immune-suppressive signatures (especially #neutrophil recruitment). Recent studies suggest pressure on the basal state
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A mitochondria-centered subcellular perspective provides a cohesive framework for understanding #neutrophil-tumor communication and may help inform the development of subcellularly targeted cancer therapies.
Learn more from Dr. Bo Pang & colleagues.
📚 https://bit.ly/49MflOQ
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#FusobacteriumNucleatum–induced #neutrophil EVs carrying NETs are internalized by intestinal epithelial cells, activating the AIM2 #inflammasome, exacerbating #UlcerativeColitis and highlighting the nEVs–NETs/AIM2 axis as a therapeutic target.
#OpenAccess: doi.org/10.1016/j.ge...
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The upregulated tRF-His-GTG-1 is then packaged into pEVs & delivered to neutrophils
link.springer.com/article/10.1...
🧨 Mechanism of #Neutrophil Activation by tRF-His-GTG-1
- Once delivered to neutrophils, tRF-His-GTG-1 interacts with TLR8 n➡️to the activation of neutrophil effector functions
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- Severe #COVID & LC are characterized by increased lipid droplet (LD) accumulation & NET release.
🧨The study outlines a dual-pathway mechanism where tRF-His-GTG-1 causes #neutrophil dysfunction
- TLR8–mTOR Activation: tRF-His-GTG-1 binds to Toll-like receptor 8 (TLR8),
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Scientists identify #EpothiloneB as a repurposed therapy for #InflammatoryBowelDisease, showing it promotes epithelial repair, reduces #inflammation, rebalances #GutMicrobiota, and induces #neutrophil #apoptosis using #zebrafish screening.
#OpenAccess: doi.org/10.1016/j.ge...
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This study shows that #BCL2 inhibitors clear #GiantCongenitalMelanocyticNevus by targeting senescent and proliferative cells, inducing immune infiltration and #neutrophil extracellular traps, and establishing durable memory responses.
#OpenAccess in #STTT: doi.org/10.1038/s413...
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Aroca-Crevillén, @drusqui.bsky.social et al. @isciiisalud.bsky.social show that a #circadian #neutrophil checkpoint protects tissues from exuberant #inflammation and can be activated to protect the host. rupress.org/jem/article/...
#CardiovascularBiology #InnateImmunity
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#Article
Neutrophil Irg1/itaconate axis protects against experimental colitis by suppressing local inflammation and maintaining hematopoietic homeostasis doi.org/10.1186/s435...
#Irg1 #Itaconate #Neutrophil #InflammatoryBowelDisease #ExperimentalColitis #IBD
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Thrilled to share this pre-print from @gnna.bsky.social PhD. We combine RNAseq with functional experiments to describe #neutrophil phenotype in older people with #frailty
@vivensa.bsky.social @livuni-ilcams.bsky.social
www.medrxiv.org/content/10.6...
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🧨 Role of #Neutrophil in #Viralinfections
@plos.org
journals.plos.org/plospathogen...
@nature.com
www.nature.com/articles/s41...
www.frontiersin.org/journals/cel...
link.springer.com/article/10.1...
www.frontiersin.org/journals/med...
www.sciencedirect.com/science/arti...
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Rainy morning can't make me sad - off to #BSI25 for some #macrophage #neutrophil (and I guess other immune cells exist) fun 😊 don't forget Wednesday 11am 'Recent advances in reproductive immunology'! Going to be fab #immunosky #bestconferenceoftheyear
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Inwardly rectifying potassium channels promote directional sensing during #neutrophil chemotaxis, say Tianqi Wang, Daniel Kim, Chang Ding, GuangJun Zhang, Qing Deng, and colleagues (Purdue University) rupress.org/jcb/article/...
#Migration #motility #Immunology
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In @jcb.org, Wang, Kim, Ding et al. of the Qing Deng lab demonstrate that inward-rectifying potassium channels maintain the resting membrane potential and are required for directional sensing during #neutrophil chemotaxis. rupress.org/jcb/article/...
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Wang, Kim, Ding et al. of the Qing Deng lab demonstrate that inward-rectifying potassium channels maintain the resting membrane potential and are required for directional sensing during #neutrophil chemotaxis. rupress.org/jcb/article/...
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Beyond its beautiful, segmented shape 🔬, the #neutrophil nucleus may be a key to understanding immune cell migration and gene regulation - but its full functional relevance remains unknown.
#Immunology #ImmunoSky #CellBiology
🔗 ino.to/bQiWo2g
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#Article in @MedComm_MC
Discovering Heterogeneous Leukocytes Subsets Associated With Alcoholic Steatohepatitis by #scRNAseq Analysis doi.org/10.1002/mco2...
#AlcoholicLiverDisease #AlcoholicSteatohepatitis #Bcell #ImmuneCell #Neutrophil #tSNEs
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This review from Ambreen, @adrover.bsky.social et al. explores cancer-elicited changes to #neutrophil behaviour and proposes ways in which these may contribute to cardiovascular pathology. rupress.org/jem/article/...
📘 In #Cytokines collection: rupress.org/jem/collecti...
#Cytokines2025
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Insights @jem.org from Andrea Cooper: Mtb drives expression of type I IFN–mediated #neutrophil accumulation, which limits interaction btwn CD4 T cells & macrophages. Failure to limit type I IFN very early in the process allows rapid progression of disease rupress.org/jem/article/...
#Tuberculosis
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Insights from Andrea Cooper: Mtb drives expression of type I IFN–mediated #neutrophil accumulation, which limits interaction btwn CD4 T cells & macrophages. Failure to limit type I IFN very early in the process allows rapid progression of disease rupress.org/jem/article/...
#Tuberculosis
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New @jhumimmunity.org study from Valagussa, Kracker et al. identifies and characterizes a novel heterozygous USB1 variant (p.P44L) in a patient with #hypogammaglobulinemia and low #neutrophil counts, showing altered protein localization and function. rupress.org/jhi/article/...
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New study from Valagussa, Kracker et al. @institutimagine.bsky.social identifies and characterizes a novel heterozygous USB1 variant (p.P44L) in a patient with #hypogammaglobulinemia and low #neutrophil counts, showing altered protein localization and function. rupress.org/jhi/article/...
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🚨 New preprint from the group - #Neutrophil myeloperoxidase as a functional biomarker for RSV severity: implications for in vitro therapeutic screening. www.biorxiv.org/content/10.1...
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William Branchett, Anne O’Garra et al. @crick.ac.uk suggest that early type I IFN signaling during M. #tuberculosis infection favors #neutrophil accumulation and limits CD4+ T cell infiltration into developing lesions. rupress.org/jem/article/...
#TB
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Type I IFN drives #neutrophil swarming, impeding lung T cell–#macrophage interactions and #TB control, say William Branchett, Anne O’Garra et al. @crick.ac.uk rupress.org/jem/article/...
#Tuberculosis
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