This echoed earlier #scRNAseq data from the lab: lung Tfh-like resident helpers (TRH) split into two subsets highly expressing Bcl6 or HIF-1α (3/10).
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#scRNAseq
Latest posts tagged with #scRNAseq on Bluesky
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Posts tagged #scRNAseq
𝗪𝗼𝗿𝗸𝗶𝗻𝗴 𝘄𝗶𝘁𝗵 𝘀𝗰𝗥𝗡𝗔-𝘀𝗲𝗾 𝗱𝗮𝘁𝗮?
One of the decisions when selecting a dataset is understanding which Chromium chemistry was used.
Understand 10X Genomics 𝗰𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝗶𝗲𝘀: v3.1 vs GEM-X v4 and how they impact dataset selection.
A reference is on the first comment.
#scRNAseq #10XGenomics #ElArkhe
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Working with single-cell RNA-Seq data and wondering where to start with the analysis?
This blog includes the main steps:
www.fiosgenomics.com/single-cell-rna-seq-data...
#omics #bioinformatics #singlecell #scRNAseq
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Using integrated #scRNAseq, #Immunofluorescence, and functional validation, this study shows that the #Immunosuppressive #TumorMicroenvironment contributes to tumor aggressiveness in lymphovascular invasion-positive #PDAC.
#OpenAccess: doi.org/10.1016/j.ge...
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🧬 In our latest issue, Deng et al. utilized scRNA-seq to uncover the potential of a specific macrophage population in kidney injury.
'Single-cell RNA sequencing reveals the protective role of renal Cx3cr1+ macrophages in cisplatin-induced acute kidney injury' ➡️ buff.ly/ooEodld
#scRNAseq #macrophage
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From #PCR, to #NGS, to #scRNAseq, yesterday’s pipe dream is today’s standard. Science follows a pattern, after all: first, something’s impossible. Then, it’s indispensable. So what’s next on that list?
Join us for a webinar this April to find out. https://bit.ly/4tJv9tD
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New to scRNA sequencing? Watch our on-demand webinar, covering scRNA-seq workflows, experimental design, data analysis & applications in oncology, immunology & precision medicine.
#SingleCell #scRNAseq #Transcriptomics #Genomics #NGS #Bioinformatics #PrecisionMedicine https://tinyurl.com/2ykr9jw5
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Collect #NeuralCrest Cells for #SingleCell #RNAseq from any vertebrate.
Our new paper, present an antibody-guided #FACS method to collect NCCs. No trans-genesis or in ovo manipulation required.
Demonstrated in wall #lizard #embryos using #microscopy, #RTqPCR and #scRNAseq.
doi.org/10.1111/ede....
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scDesign3 - although this tool doesn't have a web interface, it explores additional scenarios, such as other data modalities or even multimodal experiments
(github.com/SONGDONGYUAN...)
#bioinformatics
#scRNASeq
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This paper wouldn't be possible without my wonderful co-authors: Shuang Li, Malte Lücken, and the support from the Marioni Lab and Teichmann Lab. 🤝
Huge thanks to the reviewers and community for the feedback! #SingleCell #Bioinformatics #scRNAseq #DataScience
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Hola 👋
Preparando materiales de scRNA-seq, armé un notebook sobre Seurat v4 versus Seurat v5
Resumo los principales cambios conceptuales y estructurales que impactan scRNA-seq.
Si usas Seurat o piensas migrar a v5, puede serte útil.
🔗 cyntsc.github.io/single_cell_...
#scRNAseq #Seurat #SingleCell
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Working with single-cell RNA-Seq data and wondering where to start with the analysis?
This blog includes the main steps:
www.fiosgenomics.com/single-cell-rna-seq-data...
#omics #bioinformatics #singlecell #scRNAseq
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Join our in-person Single-Cell RNA-Seq Workshop in Berlin (March) - 3 days, fully hands-on, real data, real workflows, direct trainer support. Learn by doing, not watching.
Details & registration: www.ecseq.com
#scRNAseq #SingleCell #NGS #Bioinformatics #Berlin
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We are thrilled to share the 1st pub out of the #DukeMGC. Congrats to Lab Analyst Ellora Haukenfrers' on your 1st first author paper!
We present 'A platform-agnostic evaluation of non-formalin fixed #singlecell RNA technologies'
#benchmarking #scRNAseq
www.biorxiv.org/content/10.6...
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GPTBioInsightor—Leveraging LLMs for transparent scRAN-Seq cell type annotations. #SingleCell #scRNAseq #LLMs #AI #Bioinformatics @bioinfoadv.bsky.social 🧪🧬 🖥️
academic.oup.com/bioinformati...
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Evaluating the practical aspects and performance of commercial single-cell RNA sequencing technologies. #SingleCell #scRNAseq #Benchmarking #NARgenomicsAndBioinformatics 🧪🧬 🖥️
academic.oup.com/nargab/artic...
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I cant explain, how #beautifully #executed this paper is -I wonder, how we may #loose I#nterrogation/experimental skills like this in the #era of #scRNAseq and other modern technologies...which reveals what - #heterogeneity and #UMAPS
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Our new pre‑print is out!
scReady – an automated and accessible pipeline for single‑cell RNA‑Seq preprocessing: Empowering novice bioinformaticians
wellcomeopenresearch.org/articles/11-43
@haessar.bsky.social @fionan-a.bsky.social @yiyicheng@mastodon.social
#scRNAseq #bioinformatics
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Our new pre‑print is out!
scReady – an automated and accessible pipeline for single‑cell RNA‑Seq preprocessing: Empowering novice bioinformaticians
https://wellcomeopenresearch.org/articles/11-43
@haessar.bsky.social @fionan-a.bsky.social @yiyicheng
#scRNAseq #bioinformatics
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Weekly reads 12/1/25:
Context, benchmarks and reality checks for single-cell foundation models
open.substack.com/pub/behindth...
Big takeaway: scale helps,but context, benchmarks, and classical baselines still matter.
#SpatialTranscriptomics #scRNAseq #AIinBiology #ComputationalBiology
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Analyzing cell-type-specific isoform expression using IsoDiffR and long-read single-cell RNA sequencing. #SingleCell #LongRead #Sequencing #scRNAseq #Isoforms #DifferentialExpression #Bioinformaticcs #Genomics 🧪🧬 🖥️
academic.oup.com/bioinformati...
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scSNViz: Visualization and analysis of Cell-Specific expressed SNVs. #SingleCell #scRNAseq #SNVs #DataVisualization #Genomics #Bioinformatics 🧪🧬 🖥️
academic.oup.com/bioinformati...
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Integrating murine models and human #scRNAseq data reveals that neutrophil-derived #OncostatinM drives #AtopicDermatitis by promoting immune cell recruitment, skin inflammation, & #Pruritus-associated neuronal activation.
#OpenAccess: doi.org/10.1016/j.ge...
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Working with single-cell RNA-Seq data and wondering where to start with the analysis?
This blog includes the main steps:
www.fiosgenomics.com/single-cell-rna-seq-data...
#omics #bioinformatics #singlecell #scRNAseq
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#scRNAseq revealed that systemic JIA is characterized by intense #AcuteInflammatoryResponses and identified MIF-CXCR7/CD44 signaling as a key differentiator between systemic & non-systemic JIA joint pathology.
#OpenAccess: doi.org/10.1016/j.ge...
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CIMA maps cell type–specific regulatory networks by integrating scRNA-seq, scATAC-seq & genetics across 10M+ PBMCs, revealing causal links to immune-mediated diseases.
#SingleCell #Genomics #Immunology #MultiOmics #scRNAseq #scATACseq #HumanGenetics @science.org www.science.org/doi/10.1126/...
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💻 Stop inferring fate from separate cells. Live-seq tracks the same cell over time, giving longitudinal, causal insights from a single experiment.
🎥 Webinar & slides 👉 https://bit.ly/49tCsOz
#SingleCell #Cytosurge #Lexogen #LiveSeq #SameCell #Transcriptomics #NGS #scRNAseq
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Free #webinar! Join us as experts from #10xGenomics discuss how, together with #Novogene #NGS, we can unravel the complexities with #scRNAseq to drive your single-cell and tissue research.
January 27th / 10am GMT
Register today: bit.ly/3NaoJmv
#bioinformatics @10xgenomics.bsky.social
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👀 Check out this MorPhiC preprint by postdoc Bo Yu, @programmingsun.bsky.social, and others on a causal gene regulatory network framework combining co-expression + knockout modeling.
📖 www.biorxiv.org/content/10.6...
🔗 morphic.bio
#ComputationalBiology #Genomics #scRNAseq
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Integrating single-cell RNA-seq with spatial transcriptomics reveals immune niches and tumor architecture in testicular DLBCL.
#SpatialTranscriptomics #scRNAseq #DLBCL #TME
www.sciencedirect.com/science/arti...
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