Latest posts tagged with #antisense on Bluesky
This study reveals FUS as a key driver of fibrotic signaling in #IdiopathicPulmonaryFibrosis, with #antisense therapy (ION363) reducing profibrotic gene programs & improving patient-derived lung models, highlighting FUS as a promising therapeutic target.
#STTT: doi.org/10.1038/s413...
`These data set the stage for a potential therapeutic strategy using antisense oligonucleotides to promote isoform switching in patients with RTT who carry partially functioning alleles of MECP2.`
www.science.org/doi/10.1126/scitranslmed...
#Rett #RettSyndrome #geneTherapy #antisense
Long-read #transcriptomics of #GallbladderCancer uncovered ERBB2 i14e, a splice isoform linked to poor prognosis and #trastuzumab resistance; #antisense targeting restored sensitivity, revealing a potential #biomarker and therapeutic strategy.
#STTT: doi.org/10.1038/s413...
How can markets be made for #SyntheticBiology products? Holland suggests #Innovation will accelerate once mechanisms are in place. bit.ly/4oXBUEJ #EngineeringBiology #Patents #TechnologyTransfer #PlasticDegradation #ChemicalManufacture #Therapeutics #DrugDelivery #Antisense #GeneExpression
Researchers establish a full-length #gallbladder #transcriptome atlas using #LongReadSequencing and identify ERBB2 i14e as a novel isoform driving #TumorGrowth and trastuzumab resistance. #ERBB2 #antisense #medsky
#OpenAccess in #STTT: doi.org/10.1038/s413...
Arnatar announces publication of key patents for ACT-UP1, a first-in-class #antisense platform to #upregulate protein expression. A breakthrough for #haploinsufficient & #ProteinDeficiency diseases.
🧬 Learn more: https://bit.ly/41JBRDE
Join us for an online seminar on ASO therapy, September 24th 12.30 pm
#RNAtherapeutics #Antisense
@gbmev.bsky.social @oligogirl.bsky.social
Our next speaker is Anne-Lot van Esbroeck from the @erasmusmc.bsky.social who is going to present on the development of #antisense therapies for brain diseases. In particular Rare Diseases, which the rarity of the disorders complicates significantly the chances of a treatment.
Thrilled to see our work on targeted #mRNA blockade using high-throughput #antisense screening, now published in Advanced Science! 🚀
A true team effort in close collaboration with the @jorg-vogel-lab.bsky.social with special credit to Popella & Danti!
ASOs for the people!
bsky.app/profile/gior...
#FWakeAntiSense #AntiSense
#FWakeYouTube #FranLab #FWakeFranLab /\
#FWakeYouTubeCommunity #CascadeComments /\
#FWakeAntiReality #AntiRealityOpera /\
#FWakeContextSense #FWakeTopicContext /\
#FWakeSpamFilters #FWakeSpamFilterBypass /\
www.youtube.com/watch?v=i91n...
Check out our latest work! Preclinical in vitro and safety and in vivo biodistribution of #antisense #oligonucleotides targeting a recurrent genetic variant in ABCA4 present in patients with #Stargardt disease. A big first step towards therapeutic intervention.
www.nature.com/articles/s43...
🚨 We're hiring! 🚨
Join us at Biobizkaia 🌍 as part of the MSCA-DN EffecT project! We’re offering a fully funded #PhD position UPV/EHU. 🎓
📌 Focus on:
🔬 #Antisense #oligonucleotides
🧬 #Splicing
🌟 #Rarediseases📄
Apply now: euraxess.ec.europa.eu/jobs/296420
Info here: www.effect-dn.eu/candidates
We're hiring!!
As part of the MSCA-DN EffecT we offer a PhD position in our lab at @CBM_CSIC_UAM @UAM_Madrid to work in #antisense oligonucleotides, #splicing and #rarediseases All the information here
euraxess.ec.europa.eu/jobs/296420
