Mapping isoforms and regulatory mechanisms from spatial transcriptomics data with SPLISOSM. #SpatialTranscriptomics #Isoforms @natbiotech.nature.com š§Ŗš§¬ š„ļø
www.nature.com/articles/s41...
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#Isoforms
Latest posts tagged with #Isoforms on Bluesky
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Posts tagged #Isoforms
Analyzing cell-type-specific isoform expression using IsoDiffR and long-read single-cell RNA sequencing. #SingleCell #LongRead #Sequencing #scRNAseq #Isoforms #DifferentialExpression #Bioinformaticcs #Genomics š§Ŗš§¬ š„ļø
academic.oup.com/bioinformati...
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Genome annotations matter: characterizing Ensembl hg38 annotations from 2014 to 2023. #mRNA #GenomeAnnotation #EnsemblGenes #Isoforms #BMCgenomics
link.springer.com/article/10.1...
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Good info presented by Illumina R&D folks at ASHG last week. Isoform detection in single cells pairing Illumina 3' Single Cell RNA library prep and MiSeq i100 600 cycle kits on 50M reads flow cells. NovaSeq X 600 cycle kits not far away either!
#illumina #singlecell #isoforms #SpliceVariants
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Decoding the human PBMC isonome: Isoform-level resolution with single-cell long-read transcriptomics. #LongRead #Sequencing #RNAseq #SingleCell #Isoforms #Transcriptomics @biorxiv-genomic.bsky.social
www.biorxiv.org/content/10.1...
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ScIsoX: a multidimensional framework for measuring isoform-level transcriptomic complexity in single cells. #SingleCell #scRNAseq #Isoforms #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
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Iām really happy to present #SCALPEL, a new #Nextflow tool to quantify transcript isoforms at the single-cell level using conventional 3ā scRNA-seq data #scRNA-seq #single-cell #tools #isoforms
www.nature.com/articles/s41...
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š Three #NOX #isotypes are expressed mainly in the #brain: NOX2, NOX3 and NOX4, this study explored the expression and #cellular sources of these NOX #isoforms was investigated in the context of stress-induced #depression.
š» Read the paper on our webpage: www.thieme-connect.com/products/ejo...
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New version of our interactive data site - contains all information about our long-read sequencing of the DRG published in #PAIN @iasp.bsky.social
#isoforms
sensoryomics.shinyapps.io/RNAIsoforms/
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Nice cool study, @syncellbiolab, @anubhav_dhar, @SuchetaDey69384, @MullickSan22454, @Nishaant_PB, @deepak_iisc and Angana. Wonderful to be collaborating with you on this work and looking at #actin #isoforms in #yeast and #mammalian_cells using #UExM.
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Figure 1. Multiple RNA variables contribute to the production of distinct isoforms from the same gene. In alternative exon inclusion, an exon can be either included or spliced out of a transcript. In alternative TSS usage, transcription can start at two different positions. In alternative poly(A) site usage, the 3ā² untranslated region can vary in length. In alternative donor or acceptor site usage, the boundary between an exon and an intron can shift. In intron retention, an intron can be included in the mature mRNA.
Understanding isoform expression by pairing long-read sequencing with single-cell and spatial transcriptomic. #LongRead #Sequencing #SingleCell #SpatialTranscriptomics #Isoforms #Review @genomeresearch.bsky.social š§¬š„ļø
genome.cshlp.org/content/34/1...
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