#NKCells

The Leonardo Apheresis Platform from an Oncology Platform to an Immune Restoration Platform

2 weeks ago

A closer look at ImmunityBio’s Leonardo platform: CD3/CD14-depleted, IL-12/15/18-primed m-ceNK monotherapy followed by biomarker-guided IL-15 support — and the expansion into iNKT for lymphopenic sepsis.
#CellTherapy #Immunotherapy #NKcells

huggenberg.substack.com/p/the-leonar...

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TRAIL4Life

@trail4l.bsky.social

2 weeks ago

Disarming the Natural Killers: Mechanisms of NK Cell Dysfunction in Hematological Malignancies Natural Killer (NK) cells are innate lymphocytes that provide rapid first-line defense against infected and transformed cells through receptor-mediate…

🔗 The full article is available at the following link: sciencedirect.com/science/arti...

#NKcells #Immunology #CancerResearch #CollaborativeResearch

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@hemehub.bsky.social

2 weeks ago

🩸Facts about Multiple Myeloma:

Myeloma Biology and Microenvironment

#MultipleMyeloma #Hematology #NKcells #Cytogenetics #HEMEHUB #TP53 #NFkB #Hyperdiploidy #t1114 #del17p #HemOnc #MedEd

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The maturation process of lymphocytes and how Anktiva, an IL-15 superagonist, enhances these processes A comprehensive, step-by-step summary of the key processes in Immunology 2.0 and their potential to transform standard cancer care.

1 month ago

Why are lymphocytes often neglected in cancer treatment, and what changes are necessary?
huggenberg.substack.com/p/fundamenta...
#Immunotherapy #PrecisionMedicine #CancerResearch #NKcells #Lymphopenia #CARNK #immunosky

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11th Edition Aging & gerontology 2026

@agingcongress.bsky.social

1 month ago

Excess Cdc42 activity weakens NK cell clearance of senescent cells in aging

Third round of abstracts is now OPEN!

Submit your abstract and share your research with the global aging science community.

agingcongress.com/edition2//ab...

#Aging #Immunosenescence #NKCells #AgingResearch

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@d-and-d-world.bsky.social

1 month ago

This #WorldCancerDay, explore how boosting natural killer (NK) cell activity, from CAR‑NK therapies to NK‑cell engagers and checkpoint strategies, could strengthen our fight against cancer.

Read the open access review: https://bit.ly/4j8dKEW

#Immunotherapy #NKcells

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1 month ago

VCU researchers win $1.8 million US DoD grant for cancer therapy The US Department of Defense (DoD) grant funds engineered NK cell therapy for resistant prostate cancer.

VCU researchers awarded $1.8M DoD grant to develop a novel engineered NK cell therapy targeting incurable, advanced prostate cancer (CRPC).
#News #ProstateCancer #Immunotherapy #CRPC #CellTherapy #NKcells #IL24 #DoDgrant

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Phalguni Deswal

@phalguniddw.bsky.social

1 month ago

VCU researchers win $1.8 million US DoD grant for cancer therapy The US Department of Defense (DoD) grant funds engineered NK cell therapy for resistant prostate cancer.

VCU researchers awarded $1.8M DoD grant to develop a novel engineered NK cell therapy targeting incurable, advanced prostate cancer (CRPC).
#News #ProstateCancer #Immunotherapy #CRPC #CellTherapy #NKcells #IL24 #DoDgrant

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Critical Reviews in Immunology

@crijournal.bsky.social

1 month ago

Continuing our tribute to Dr. Anahid Jewett's immunology work: Dr. Jewett and colleagues examine how NK and CD8+ T cells contribute to ALS pathogenesis, discussing targeted therapies including supercharged NK cells.

Free until Feb 15: www.dl.begellhouse.com/references/2...

#ALS #NKCells

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Critical Reviews in Immunology

@crijournal.bsky.social

1 month ago

In honor of Dr. Anahid Jewett's legacy, we're highlighting her contributions to immunology. This review explores how probiotics activate NK cells, enhance cancer therapeutics, and reverse functional impairment.

Read free until Feb 15: www.dl.begellhouse.com/journals/2ff...

#Probiotics #NKCells

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Critical Reviews in Immunology

@crijournal.bsky.social

1 month ago

This comprehensive review by Dr. Anahid Jewett and UCLA researchers demonstrates how NK cells select and differentiate cancer stem cells, leading to growth inhibition and reduced metastasis.

Free to read until Feb 15th:
dl.begellhouse.com/journals/2ff...

#NKCells #CancerImmunotherapy

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Cancer Survivors Club 📙

@thecancersurvivorsclub.com

2 months ago

Scientists Unveil Breakthrough Method to Mass-Produce Cancer-Fighting Natural Killer Cells A new method for engineering natural killer cells could make cancer immunotherapy more efficient, scalable, and affordable, potentially reshaping how these treatments are produced.

Scientists unveil breakthrough method to mass-produce cancer-fighting NK cells.
Scaling CAR-NK therapy could bring powerful immune treatments to far more patients. Big science, real hope.
scitechdaily.com/scientists-u...
#CancerResearch #Immunotherapy #NKCells #CAR #TCSC

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Journal of Experimental Medicine

@jem.org

2 months ago

Bringing Natural killer cells to the clinic: opportunities beyond #cancer. New review from Marjorie Cayatte, Valentin Picant, Marie Vétizou, and Eric Vivier @ciml.bsky.social: rupress.org/jem/article/...

#Autoimmunity #NKCells #Neurodegeneration

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Rockefeller University Press

@rupress.org

2 months ago

New review in @jem.org by Cayatte, Picant, Vétizou, & @ericvivier.bsky.social explores the expanding roles of #NKcells beyond #cancer, highlighting their pivotal functions in viral #infections, #neurodegeneration, #autoimmune diseases, and #transplantation medicine rupress.org/jem/article/...

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Journal of Experimental Medicine

@jem.org

2 months ago

New review by Cayatte, Picant, Vétizou, & @ericvivier.bsky.social @ciml.bsky.social explores the expanding roles of #NKcells beyond #cancer, highlighting their pivotal functions in viral #infections, #neurodegeneration, #autoimmune diseases, and #transplantation medicine rupress.org/jem/article/...

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Tobias Bexte

@bextetobias.bsky.social

3 months ago

Frontiers | Engineering with care: safety assessment platforms for CRISPR-modified natural killer cells CRISPR-based gene editing has become a transformative tool to enhance immune cell therapies. In particular, engineering natural killer (NK) cells with CRISPR...

🚨Paper alert! Happy to share our review on safety assessments for gene-edited #NKcells. A highly timely topic for future multiplex-edited NK cells!
Proud of my first senior authorship together with safety-tool expert Toni Cathomen. Congratulations to Alieh for fantastic work! tinyurl.com/4b4f6383

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Lund Stem Cell Center

@lundstem.bsky.social

3 months ago

🧫 Natural Killer cells are key defenders against infection and cancer.

At last month’s Stem Cell Talk, Prof. Ewa Sitnicka-Quinn shared new insights into how they develop & how this knowledge may support future NK-cell–based therapies. #NKcells

Read More:
👉 www.stemcellcenter.lu.se/research-gro...

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3 months ago

A regulatory pathway to establish a cancer therapy platform based on #Immunotherapy , avoiding #Lymphopenia caused by chemotherapy and radiation, with full patent protection. tinyurl.com/437xrx77
#immunology #PrecisionMedicine #CancerResearch #NKcells #Lymphopenia #CARNK #immunosky

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Engineered “natural killer” cells could help fight cancer Researchers found a way to engineer CAR-NK immune cells that makes them much less likely to be rejected by the patient’s immune system, a common drawback of this type of cancer immunotherapy.

4 months ago

How Natural Killer cell lysate reduces the damage caused by Lymphodepletion in T-cell therapies
#immunosky #medsky #NKcells #Cancer #Cytokines

cloud.hoststar.ch/s/aecHWe5LXS...

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Whoa 🤯 in Slow-Mo

@0lsi.bsky.social

4 months ago

⚡ Stayed active longer than usual
💥 Avoided dangerous immune storms that sometimes affect #CAR-T therapies
A huge leap toward safer, longer-lasting cancer #immunotherapies! 🙌
#CancerResearch #Biotech #MIT #Harvard #NKCells #FutureOfMedicine

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@aginigfencer.bsky.social

4 months ago

From CAR-NK cells to checkpoint inhibitors, Blunt & Khakoo review how boosting NK-cell function could transform cancer therapy.

🔓 Open access: https://bit.ly/4j8dKEW

#Immunotherapy #NKcells #CancerResearch

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Karolinska Institutet

@ki.se

5 months ago

Concept image from Getty Images, defence against the coronavirus

A new KI study published in Nature Immunology shows that CD56bright #NKcells temporarily reside in our organs and then leave them via the lymphatic system. The results change our understanding of how the immune system works in human organs. #Immunology 🧪 news.ki.se/the-immune-s...

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5 months ago

NK50 meeting for #NKcells @ki.se celebrating 50 years about to begin

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Djaoud Lab

@djaoudlab.bsky.social

5 months ago

Novel trispecific killer engager targeting B7-H3 enhances natural killer cell antitumor activity against head and neck cancer Background Patients with head and neck squamous cell carcinoma (HNSCC), particularly the human papillomavirus negative (HPV −) subset, have a dismal prognosis. Furthermore, patients with Fanconi anemi...

At today’s lab journal club, we discussed PMC12306285: a trispecific killer engager targeting B7-H3 that boosts NK cell activity against head & neck cancer, even under hypoxia.
#Immunotherapy #NKcells
#CancerResearch #ImmunoSky
jitc.bmj.com/content/13/7...

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5 months ago

🧬 New in Immunotherapy Advances:

Cytokine-induced memory-like NK cells + Tafasitamab show strong efficacy against B-cell ALL, boosting cytotoxicity & survival in vivo.

Open Access 👉 https://bit.ly/48oztXa

#Immunotherapy #NKcells

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Jen L, PhD

@drjkyl.bsky.social

5 months ago

Design of an artificial natural killer cell mimicking system to target tumour cells
Journal of Tissue Engineering
@journals.sagepub.com

journals.sagepub.com/doi/10.1177/...

#immunotherapy #nanomedicine #NKcells #targeteddrugdelivery #openaccess

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