Latest posts tagged with #Pathogenesis on Bluesky
An overview of the molecular #Pathogenesis of #Osteoarthritis, detailing the signaling pathways involved and highlighting emerging therapeutic strategies that ameliorate both #CartilageDegradation and clinical manifestations of OA.
#OpenAccess: doi.org/10.1038/s413...
This study provides a new perspective for elucidating the #pathogenesis of #Alzheimersdisease and also establishes a foundation for the development of precise treatment strategies, offering multiple possibilities for clinical translation.
#OpenAccess: bio-integration.org/alzheimers-d...
#Pathogenesis of #H5N1 Clade 2.3.4.4b in dry Jersey #cows following intramammary inoculation shows within-host compartmentalization, etidiohnew.blogspot.com/2026/03/path...
This review summarizes the significance of different small noncoding RNAs (#sncRNAs) in #CardiovascularDisease #Pathogenesis, detailing their regulatory roles and potential applications as #Biomarkers & #TherapeuticTargets.
#OpenAccess: doi.org/10.1016/j.ge...
HtrA’s chaperone and proteolytic activities are crucial for H. pylori survival and infection — making it a promising #DrugTarget. This review summarizes HtrA structure and function, its role in #infection and #pathogenesis, and the challenges of its therapeutic targeting 💊
doi.org/10.1002/1873...
Introducing RMzyme, a #Multiomics platform mapping RNA-modifying enzymes across 63 human tissues to elucidate how #Epitranscriptomic regulation and PTM networks drive cellular function and disease #Pathogenesis.
#STTT #OpenAccess: doi.org/10.1038/s413...
This review explores how #HistoneDeacetylases regulate #VascularHomeostasis via endothelial and smooth muscle cells, highlighting their role in vascular #Pathogenesis and the therapeutic potential of #HDACinhibitors.
#OpenAccess: doi.org/10.1016/j.ge...
Establishment and characterization of a novel cell line from Culex tritaeniorhynchus for arbovirus and arthropod-specific virus research
Researchers establish CtrE1, a highly susceptible and genetically tractable stable cell line derived from Culex tritaeniorhynchus, for investigating the replication kinetics & #Pathogenesis of major #Arboviruses & arthropod-specific viruses.
#OpenAccess: doi.org/10.1016/j.dc...
Quantitative framework for pathogen threat assessment based on structural and biochemical features: lack of D-amino acid usage, coherent fractal morphology, and Hz-level oscillations.
@NIH @CDCgov @WHO @NIAIDNews @NatureMicrobiol #Pathogenesis #SystemsBiology #FractalBiology
doi.org/10.1016/j.bi...
Transfer RNA-derived small RNAs (tsRNAs): A rising star in liquid biopsy
This review characterizes tsRNAs as high-potential #Biomarkers for #LiquidBiopsy, detailing their biogenesis and stability in biofluids, their roles in disease #Pathogenesis, and their application as non-invasive biomarkers.
#OpenAccess: doi.org/10.1016/j.ge...
Insights into the interplay between #ERstress & necroptosis, detailing the regulatory role of UPR in the #Pathogenesis of necroptosis-related diseases, & the therapeutic potential of targeting UPR-mediated pathways.
#OpenAccess: doi.org/10.1016/j.ge...
Reviewing the structures, functions, and the molecular mechanisms through which FXYD proteins regulate ion transport, while highlighting their roles in the #Pathogenesis of various diseases and their therapeutic potential.
#OpenAccess: doi.org/10.1016/j.ge...
Decoding the host-pathogen-environment interaction: Integrated insights into Helicobacter pylori virulence and epidemiological transmission
By integrating insights into bacterial virulence and host-environment interactions, this study provides a multi-dimensional framework for understanding H. pylori #Pathogenesis and its evolving epidemiological profile.
#OpenAccess: doi.org/10.1016/j.dc...
which allows these B cells to survive .Once rescued, these B cells initiate inflammatory demyelination through B cell-receptor or antibody-dependent mechanisms & participate in inflammatory demyelination
#Bcells are implicated in the #pathogenesis of MS,
Now available on demand! 🍄 Fungal Pathogens: Emerging Threats & Future Challenges
Watch from anywhere and explore the latest insights in fungal pathogenesis and infectious diseases.
👉 Purchase today: keysym.us/KSFungalPath...
#KSFungalPath26 #FungalPathogens #InfectiousDiseases #Pathogenesis
Decoding the host-pathogen-environment interaction: Integrated insights into Helicobacter pylori virulence and epidemiological transmission
This review explores the mechanisms of #Hpylori #Pathogenesis, the host and environmental factors influencing its #Virulence, and its primary transmission routes to provide insights into its #Diagnosis and prevention. #MedSky
#OpenAccess: doi.org/10.1016/j.dc...
#Pathogenesis and #Research #Models of Acute #Influenza-Associated #Encephalitis / #Encephalopathy: An Update, etidiohnew.blogspot.com/2026/01/path...
New study reveals a high-resolution genetic map of how E. coli adapts to the gut, showing diet- and inflammation-dependent metabolism, niche shifts, and unexpected roles for mobile genetic elements.
✍️ @amandinemaire.bsky.social & coll.
📖 shorturl.at/DYSTv
#Microbiome #Pathogenesis #Microsky
#Research
Atrial fibrillation: from pathogenesis to novel treatment options doi.org/10.1186/s435...
#AtrialFibrillation #AF #Pathogenesis #CryoballoonAblation #PulmonaryVeinIsolation #PVI #Pulsed_fieldAblation #PFA
Basic Science and Pathogenesis.
Eberlin, Livia Schiavinato et al.
Paper
Details
#BasicScience #Pathogenesis #EberlinResearch
This review on #GATA6 elucidates its crucial role in pancreatic physiology and its involvement in #PancreaticDuctalAdenocarcinoma #Pathogenesis, while highlighting it as a potential #Biomarker & #TherapeuticTarget.
#OpenAccess: doi.org/10.1016/j.ge...
Pathogenesis, Host Resistance and Integrated Management of Sugarcane Smut Caused by Sporisorium scitamineum: A Comprehensive Review
#diseasemanagement
#hostresistance
#multi‐omics
#pathogenesis
#Sporisorium
#sugarcane
pmc.ncbi.nlm.nih.gov/articles/PMC...
#Review in #MedComm
Alcohol-Related Liver Disease and #Metabolic Dysfunction-Associated Steatotic Liver Disease: Molecular #Pathogenesis and Therapeutic Interventions doi.org/10.1002/mco2...
#ALD #ImmuneRegulation #IntestinalMicrobiota #MASLD
This review discusses #MitochondrialDysfunction in #ParkinsonsDisease (PD), its molecular mechanisms, and the role of mitochondrial dysfunction in aging microglia and astrocytes in PD #Pathogenesis, highlighting future research directions.
#OpenAccess: doi.org/10.1016/j.ge...
A review on m6A methylation regulation & its biological functions in the #ImmuneSystem, detailing its critical role in the #Pathogenesis of #AutoimmuneDiseases, identifying potential #Biomarkers & targets for their prevention & treatment.
#OpenAccess: doi.org/10.1016/j.ge...
An overview of the #Epidemiology of #SystemicLupusErythematosus, key determinants of its #Pathogenesis, diagnosis characteristics, risk factors, and current preventive/therapeutic strategies. #medsky
#STTT #OpenAccess: doi.org/10.1038/s413...
Nutrient Acquisition Drives Edwardsiella tarda Pathogenesis in Necrotizing Soft Tissue Infection
Akeda, Y. et al.
Paper
Details
#Pathogenesis #InfectiousDisease #EdwardsiellaTarda
A comprehensive overview of the structure and function of #MolecularChaperones, their physiological mechanisms, and their roles in disease #pathogenesis, with insights into strategies targeting chaperone systems. #medsky
#STTT #OpenAccess: doi.org/10.1038/s413...
An overview of lysophosphatidic acid signaling, its role in physiology & #Pathogenesis of various diseases, #Diagnostic & therapeutic potential, and how AI models enable predictive simulation for precision medicine.
#STTT #FeaturedArticle #OpenAccess: doi.org/10.1038/s413...
